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 An Illustrated History of Gas Chromatog...
LabTube Meets Eric Denoyer, PhD, Agilent...Learn to pipette like a pro...Behind the Science, ep. 13: SPE vs. matr...

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How to Optimize Sample Preparation Step Prior to ExtractionHow to Optimize Sample Preparation Step Prior to Extraction
Discover the benefits of bead-binding for sample preparation in this on demand webinar from Bertin Technologies.
Advancements in Automated Sample Preparation, STR-PCR, and CE Detection for Rapid Nucleic Acid Analysis on an Integrated Microfluidic PlatformAdvancements in Automated Sample Preparation, STR-PCR, and CE Detection for Rapid Nucleic Acid Analysis on an Integrated Microfluidic Platform
Professor Frederic Zenhausem, Center for Applied Nanobioscience and Medicine, speaking at Lab on a Chip World Congress 2013.

Market Reports
Scientific News
3D-Printing in Science: Conference Co-Staged with LABVOLUTION
LABVOLUTION 2017 will have an added highlight of a simultaneous conference, "3D-Printing in Science".
Sequencing Soviet Anthrax
Next generation genomic analysis used to probe the former USSR’s biological weapons program.
Identifying People Using Human Hair Proteins
In an important breakthrough for the forensic science community, researchers have developed the first-ever biological identification method that exploits the information encoded in proteins of human hair.
Origin of Cultured Cells: Not Where You Think
Study shows cultured cells from decades-old cell line does not originate from the patient it was claimed to derive from.
Bringing NGS to the Crime Lab
New technology being validated in BCI lab for use in Ohio missing persons cases.
How Cloud Connectivity Can Combat the Reproducibility Crisis
This infographic explains the reproducibility crisis, and how cloud connectivity can help overcome this problem.
Detecting Drug Use in Hair
Scientists at Wageningen UR have developed a faster and more accurate method for the detection of drug use using hair.
Eliminating Doubt in Criminal Investigations
New ASU certificate to help curb error, misunderstanding in the quest for justice.
Determination of 13 Organic Toxicants in Human Blood
Researchers have utilised liquid-liquid extraction coupling HPLC-MS/MS to identify and quantify organic toxicants in human blood.
Rhino DNA Bank Aids Anti-Poaching Fight
At the University of Pretoria's Veterinary Genetics Laboratory (VGL) at Onderstepoort, Dr Cindy Harper and her team have developed a ground-breaking technique to collect and catalogue DNA from rhinos and rhino horns.
Business News
smartLAB 2017: For Tomorrow’s Intelligent Laboratories
smartLAB 2017 will be held 16-18 May at LABVOLUTION along side BIOTECHNICA life sciences show.
Improving the Identification of Missing People Using NGS
Collaboration targets “Sample to Insight” sequencing solutions to enhance research and applications in human identification.
New Standards for Forensic Grade Manufacturing Integrated At Promega
With recent approval in meeting the new ISO 18385 standard, Promega Corporation will be including a "Forensic Grade" classification on products used for human identity by crime labs, government agencies and paternity testing labs worldwide.
Thermo, Hamilton Partner on Forensic Automation
Thermo Fisher Scientific and Hamilton have signed a strategic agreement to provide human identification customers with fully automated platforms and reagents to eliminate potential manual errors and increase productivity in the lab.
Trajan Acquires LEAP Technologies
Bringing LEAP into the Trajan Group will complement the widening capability of Trajan.
DNA Diagnostics Center Acquires All About Truth DNA Services
DNA Diagnostics Center announces the acquisition of All About Truth DNA Services, a regional provider of DNA testing services.
Georgetown Receives $10m for Holocaust Research
Gift from Norman and Irma Braman will enhance work at Georgetown’s Center for Jewish Civilization.
Collaboration to Develop New Forensic Methods
Waters’ Centers of Innovation Program recognizes forensic chemistry laboratory at the University of Copenhagen.
It is All About the Product, Right?
Technology Networks met with Waters Corporation at its head office in Milford, MA to better understand the factors they use to drive business success.
Growing Demand for Technologies to Tackle Cybercrime to Drive Digital Forensics Market
The market is expected to reach US$4.97B by the end of 2021 at a positive CAGR of 12.5%.

27 Oct 2016
BIT'S 3rd International Congre ...
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The Biology of Anthrax Confere Company Logo
15 Nov 2016
The Biology of Anthrax Confere ...
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07 Mar 2017
The 2017 Forensic Forums ...
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2nd Annual Genetics in Forensi
14 Mar 2017
2nd Annual Genetics in Forensi ...
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A Novel Benchtop Time-of-Flight GC-MS System for High Performance Analysis of Human Urine
LECO Corporation

A workflow was developed and implemented for the effective comparison of urine. It involved the preparation of stable compounds through derivatization, data acquisition using a high performance benchtop TOFMS, comprehensive data processing (NonTarget Deconvolution™), and quick retrospective analysis of rich datasets using Target Analyte Finding.

Platform Agnostic Data Processing Routine for Targeted and Untargeted Metabolite Identification in Drug Discovery
1Advanced Chemistry Development, Inc. (ACD/Labs), 8 King Street East, Toronto, ON. M5C 1B5. Canada; 2ACD/Labs, Moscow, Russia

A discussion of a new informatics solution that addresses common challenges in metabolite identification and characterization--from LC/MS data processing and metabolites prediction to reporting and databasing of assembled biotransformation knowledge.
Accurate Mass Spectral Database: Harnessing the Power of High Performance Mass Spectrometry at Long Last
LECO Corporation, Moscow State University

Standard mixtures comprising of alkanes, PAHs, semivolatiles, and pesticides were analyzed using a high resolution time-of-flight (HRTOF) mass spectrometer—Pegasus GC-HRT (LECO Corporation, Saint Joseph,MI)—at 10 spectra-per-second (m/z40–300) in high resolution mode (25,000 at FWHH). The resulting chromatographic peaks were automatically found, deconvoluted, and curated into an Accurate Mass Library (AML).
Automated Sample Preparation of Whole Blood for Therapeutic Drug Monitoring and Diagnostics by LC-MS using a Commercial Autosampler
1 University of Applied Sciences and Arts Northwestern Switzerland FHNW, Institute for Chemistry and Bioanalytics , Gründenstrasse 40, 4132 Muttenz; 2 CTC Analytics AG; Industriestrasse 20, CH-4222 Zw

In this poster the parameters necessary to automatically prepare whole blood samples for online LC-MS applications in the field of diagnostics and TDM have been investigated. A strategy and the most important parameters are shown for the optimization of a PAL RTC autosampler
for the preparation of whole blood samples.
A Unified Software Platform for Laboratory Informatics
Advanced Chemistry Development, Inc. (ACD/Labs), Toronto, Canada.

Reported here are capabilities in automated workflows involving analytical data with chemical structures. Specifically described is automated homogenization of data from a set of instruments, including NMR structure verification, as one solution.
Instrumental Investigations: A Laboratory Manual of Forensic Analytical Chemistry
Oberlin College

A laboratory manual for undergraduate analytical and forensic chemistry courses
Determination of C2-C12 Aldehydes in Water by SPME Arrow On-Fiber Derivatization and GC/MS
1 BGB Analytik AG, Lettenstrasse 97, 8134 Adliswil, Switzerland; 2 CTC Analytics AG, Industriestrasse 20, 4222 Zwingen, Switzerland

A method applying SPME Arrow extraction and on-fiber derivatization for the quantitation of C2-C12 aldehydes in water by GC/MS is described.
Assessing Diversity in Cassava through the Application of Metabolomics
aSchool of Biological Sciences, Royal Holloway University of London, Egham, UK bInternational Center for Tropical Agriculture, CIAT

In the present study metabolomic platforms have been established for Cassava and used to assess the biodiversity present in Cassava germplasm collections and elucidate underlying biochemical mechanisms associated with traits of interest.
A KNIME Pipeline for the Analysis of GC-MS Data in Metabolomics
1Department of Biomedical Sciences, Section of Pathology, University of Cagliari, Italy; 2Department of Life and Environmental Sciences, High Resolution Mass Spectrometry Laborat

A KNIME pipeline was developed to perform pre-processing of GC-MS data in an automated way and applied to a Inflammatory bowel diseases case study
PredRet: Prediction of Retention Time by Direct Mapping between Multiple Chromatographic Systems
Department of Food Quality and Nutrition, Research and Innovation Centre, Fondazione Edmund Mach, San Michele all’Adige (TN), Italy.; Department of Stress and Developmental Biology, Leibniz Institute

Retention time (RT) information is under-utilized in LC-MS based metabolomics and sharing of RTs between systems is not currently possible. PredRet is a new system that allows highly accurate mapping and prediction of RTs between LC systems.
Application Notes
Forensic Analysis of an Artificial Sweetener Commonly Employed in Hoax Powder Attacks using Morphologically Directed Raman Spectroscopy
Malvern Instruments Limited

This application note details how Morphologically Directed Raman Spectroscopy (MDRS) using the Morphologi G3-ID can be applied to the forensic identification of commercially sourced white powders commonly used in hoax powder attacks.
Sample preparation with the AC Extraction Plate: extraction of urinary THC metabolites for LC-MSMS quantification
Tecan Group Ltd.

In many countries, routine workplace drug testing involves screening for the free THC-COOH metabolite obtained by hydrolyzing THC-COOH glucuronide. Tecan’s AC Extraction Plate with TICE technology enables a straightforward workflow that is reproducible and cost efficient. Liquid chromatography coupled with tandem mass spectrometry (LC-MSMS) provides an easy and cost-effective means for fast, sensitive and precise analysis of THC and its metabolites.
Trends, Challenges and Strategy in the Forensic Science Sector
Netherlands Forensic Institute

The forensic science sector is in transition. New insights, technologies, and customers, combined with falling costs and increasing capabilities cause the sector to grow rapidly. As a consequence the role of forensic laboratories is changing.
The Analysis of Common Drugs of Abuse in an Oral Fluid Matrix using a New Q TRAP® Platform

The multiplexing analysis of several compound classes, such as common prescription drugs along with drugs of abuse is very important. The measurement of these drugs has generally been performed using urine as the sample matrix. However, many research laboratories are finding the need to analyze these compounds in oral fluid matrices.
Quantification of Ethylglucuronide in hair by Liquid Chromatography Tandem Mass Spectrometry

An advantage of the use of ethylglucuronide (ETG) in hair is that it is not subject to the effect of bacteria. It also offers the opportunity to extend the window of detection up to 6 months compared to hours- days in blood and urine.
Advanced Automated Library Searching for Compound Identification in Forensic Toxicology Samples

LC-MS/MS utilization in forensic toxicology screening for drugs and drug metabolites has become increasingly popular due to the selectivity, sensitivity and the speed of LC-MS/MS analysis. MS/MS confirmation with automated searching against available spectral libraries has proven to add a superior level of confidence to the compound identification.
A Complete Forensic Toxicology Screening Procedure for Drugs and Toxic Compounds in Urine and Plasma Using LC-MS/MS
Thermo Scientific

Implementation of liquid chromatography-mass spectrometry (LC-MS) for forensic toxicology screening provides specific and sensitive analysis of drugs and toxic substances.
Performance Evaluation of a Thermal Desorption System for Detection of Basic Drugs in Forensic Samples by GC/MS

Stir bar sorptive extraction (SBSE) is an innovative sample extraction technique that can be used to process blood, urine, and tissue samples for routine drug screening in the forensic toxicology laboratory.
Toxicological Screening with the Agilent 6500 Series Accurate_mass Q-TOF LC/MS and personal Compound Database and Library using the Brorcker, Herre and Pragst Accurate Mass Spectral Library
Agilent Technologies

Screening using accurate mass measurement and a large database containing compounds of toxicological and forensic concern is possible with the Agilent Forensic Toxicology Personal Compound Database.
Toxtyper™ – a Comprehensive LC-MSn Screening Solution for Clinical and Forensic Toxicology
Bruker Corporation

In the clinic and the routine lab, fast and unambiguous identification of toxic compounds is the primary task. The screening solution presented here is based on ultrahigh performance liquid chromatography (UHPLC) coupled to an LC-MSn ion trap system.
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