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Webcasts
Advancements in Automated Sample Preparation, STR-PCR, and CE Detection for Rapid Nucleic Acid Analysis on an Integrated Microfluidic PlatformAdvancements in Automated Sample Preparation, STR-PCR, and CE Detection for Rapid Nucleic Acid Analysis on an Integrated Microfluidic Platform
Professor Frederic Zenhausem, Center for Applied Nanobioscience and Medicine, speaking at Lab on a Chip World Congress 2013.
The Detection of Transcription Errors in Biological SystemsThe Detection of Transcription Errors in Biological Systems
Kelley Thomas, University of New Hampshire, speaking at Genomics Research 2013.

Market Reports
Analytical Instrument Market in the US 2014-2018
Infinity Research

TechNavio's report focuses on the US and has been prepared based on an in-depth market analysis with inputs from industry experts.
High Throughput Screening (HTS) Market by Technology, Applications, and End Users - Forecast to 2018
MarketsandMarkets

Technological advancements and flourishing outsourcing industry likely to propel the growth of the global high throughput screening market. In this report, the global high throughput screening market has been segmented on the basis of technology, products, applications, end users, and geography.
Chromatography Reagents Market By Type, Bed Shape, Mobile Phase, Separation Mechanism & End User - Global Forecasts to 2018
MarketsandMarkets

The market is expected to witness a high growth due to high demand of chromatography reagents in the growing pharmaceutical market.
Facial Recognition Market: Global Advancements, Emerging Applications, Business Models and Worldwide Market Forecasts and Analysis (2013 ? 2018)
MarketsandMarkets

The report is focused to give a birds eye-view of the complete facial recognition industry with regards to technology and solutions, software, hardware and services. It also provides revenue distribution of the market based on various industry vertical or end-users.
Biomarkers Market 2013 - 2020
Allied Market Research

Disease diagnostic application remains the key area of application that is expected to reach 6.1 $billion in 2020. However, application of diagnostic biomarkers in forensics and molecular diagnostics is catching up quite significantly. Molecular diagnostics is expected to grow at a CAGR of 17.6% from 2013 to 2020.
DNA Sequencing
RI Technologies

This report presents an in depth analysis of DNA sequencing market. The study emphasizes on both, the methods and instruments/software of DNA sequencing in medical research, agriculture and animal husbandry and DNA testing and forensics application areas.
Life Science Software 2013: Markets and Opportunities
Biopharm Reports

This reports into in the life science field examines the use of specialist software and databases relating to the conduct of PCR, DNA sequencing, DNA microarray, flow cytometry, mass spectrometry and disease biomarker studies. The studies were carried out to assist software developers and vendors to identify market opportunities in these fields.
DNA Sequencing 2013: Market Developments, Growth Areas and Opportunities
Biopharm Reports

DNA sequencing is important in all areas of biological research and increasing demand for this technique is driving advances in this field, in the form of next-generation techniques. Today, laboratories use a number of different sequencing methods, however common goals include increasing throughputs and speeds, while reducing costs.
Life Science Consumables 2013: Markets and Opportunities
Biopharm Reports

Techniques such as PCR, DNA microarray, DNA sequencing, mass spectrometry and flow cytometry have grown significantly in the last decade and by 2015 markets for these five areas are expected to exceed $50 billion, globally. In these and related fields, consumables are generally the second or third largest area in cost terms, after instrumentation.
Flow Cytometry 2013: A Focus on Sales Growth
Biopharm Reports

Flow Cytometry 2013 presents the findings of a global market study of flow cytometry, involving the participation of 277 buyers and end-users in this field. With a focus on market development, sales growth and commercial opportunities, the study profiled current and evolving areas of this market, as outlined below.
Scientific News
Using Forensic Technology to Track Down Drug Residues in Milk
Veterinarians at Iowa State University are using advanced forensic techniques and the same technology used by crime scene investigators to monitor drug residues in milk and meat.
Technique Offers Arson Investigators Faster, More Accurate Results
The new process for analyzing debris for traces of fire accelerants is faster and more accurate than conventional methods and produces less waste.
Truth About Richard III’s Spinal Condition Uncovered
Scientists use 3D scans in research led by the University of Leicester, working with the University of Cambridge, Loughborough University and University Hospitals of Leicester.
ELISA Screening to Monitor Illegal and Legal Drugs in Hair and Urine
The German driving licence re-granting programme uses cut-offs many orders of magnitude below the conventional cut-offs and hence below what most of the commercially available screening kits were manufactured for.
Detecting Trace Amounts of Explosives With Light
The sensor that can detect tiny quantities of explosives with the use of light and special glass fibres.
Will Forensic Biology Become Forensic Molecular Biology?
The article presents some examples of the potential for new molecular biology technologies to assist in the investigation of crime.
Fluorescent Sensor Detects Date Rape Drug Within Seconds
The sensor, developed by researchers from the National University of Singapore (NUS), identifies the presence of GHB, a drug known commonly used to spike beverages.
Innovative Fingerprint Analysis is Trialled by Police
Pioneering technology designed by Sheffield Hallam University to provide an in-depth analysis of fingerprints is being tried and tested at crime scenes.
What can Investigators Really Tell from Gunshot Residue?
Researchers have developed a novel approach to improve gunshot residue fingerprinting to rapidly detect a wider range of particles than existing methods.
3-D Model Links Facial Features and DNA
An international team of researchers is beginning to connect genetics with facial features, degrees of femininity and racial admixture.
Business News
FBI Approves Life Technologies' Forensics Kit
Ability to upload forensic samples to National DNA Index System using GlobalFiler DNA chemistry enables faster, more powerful data comparisons to solve crimes in the U.S. and globally.
ASMS 2014 Overview
We take a look at some of the major new product announcements from ASMS 2014.
Shimadzu, Indigo BioSystems Announce Partnership
The companies will leverage the power of ASCENT™ clinical solutions on ultra-fast mass spectrometry platforms.
Operation Pangea VII Shuts Down Thousands of Illicit Online Pharmacies
The operation led to 237 arrests worldwide and the seizure of nearly $36M worth of potentially dangerous medicines.
FLUIDX Joins NFI in Automation of DNA-Profiling of Crime Scene Samples
Automating this process reduces the possibility of manual errors, lowers contamination risk, and offers the ability to run analyses overnight.
First State-Wide deployment of the RapidHIT® System
IntegenX Inc. announced the first state-wide deployment of the RapidHIT System for real-time matching of DNA profiles.
Thermo Reports 22% Revenue Rise in Q1 2014
Results include the addition of Life Technologies as of February 4, 2014, and exclude the previously announced related divestitures as of March 22, 2014.
IntegenX Announces ISO 9001:2008 Certification
Company awarded the ISO 9001:2008 certification for the design, development, manufacture, and distribution of automated DNA identification systems.
AAFS Announces 2014-15 Officers and Board of Directors
The American Academy of Forensic Sciences (AAFS) is governed by an 18-member board of directors, which includes 11 Academy members who are elected by their respective sections.
GE, NetBio to Validate Fully Integrated Rapid DNA system
Verification by forensic laboratories is a key step toward responsible adoption for crime laboratory and in-the-field law enforcement use.

Events
2014 Green Mountain DNA Confer
28 Jul 2014
2014 Green Mountain DNA Confer ...
More Information
ANZFSS 2014
31 Aug 2014
ANZFSS 2014 ...
More Information
International Symposium on Hum
29 Sep 2014
International Symposium on Hum ...
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IAFS 2014
12 Oct 2014
IAFS 2014 ...
More Information

ePosters
Comparison of Three Methods for the Evaluation of Cytokine Storm Risk in Early and Clinical Stage Biopharmaceutical Development
ReachBio LLC

Objective: To identify an assay that can accurately predict the risk of CRS and CS associated with investigational biotherapeutics. A comparison of three methods were used: (a) immobilization of test antibody on plastic, (b) co-culture of PBMC's on HUVEC's and (c) pre-culture of PBMC's at high cell density.
Isolation, Identification, and Determination of Designer Anabolic Steroids Commonly Found in Dietary Supplements
U.S. Food and Drug Administration, Forensic Chemistry Center

A general analytical approach in identifying emerging steroid-like compounds is presented, including analysis by GC-MS, LC-MS, and/or HPLC-UV. Isolation of unknown compounds was achieved by high performance liquid chromatography with fraction collection. Isolated compounds were characterized by Nuclear Magnetic Resonance spectroscopy and high resolution accurate mass-mass spectrometry to elucidate their structure.
A Mass Spectrometer for Elemental Analysis based on Fieldable Technologies
The University of Tampa Department of Chemistry, Biochemistry, and Physics, Gerling Applied Engineering

Laser ablation and a Microwave Plasma Torch (MPT) were coupled in order to obtain elemental information from solid samples. The MPT was incorporated as a less costly and more portable alternative to the ICP. MPT was also added to help improve the signal from just the laser ablation alone.
Combining low and high volume liquid handling capabilities for ADME screening
TTP Labtech, Tecan Group, F.Hoffman-La Roche Ltd

In this study we demonstrate the integration of two liquid handlers to extend the volume dispensing range creating low-volume assay-ready plates with high accuracy and precision. This was then successfully applied to a CYP inhibition assay.
Molecular Dynamics Simulation Study of Pulmonary Surfactant Interacting With Nanoparticles
University of Karachi

MD simulation studies using NAMD of lipid bilayers supported on alpha-quartz (nanoparticles) and kaolinite with explicit water molecules will be presented to understand the physiochemical effects of nanoparticles on pulmonary surfactant.
Highly Efficient Activated Carbon From Palm Shell as an Adsorbent of Toxin/Poison
International Islamic University Malaysia

Highly efficient activated carbon as an adsorbent of toxins has been successfully produced from palm shell through chemical activation process using phosphoric acid as activating agents.
Colony Forming Cell (CFC) Assays Predict for Increased Clinical Neutrophenia with Combination Therapies
ReachBio LLC

This study aimed to assess if the CFC assay could also be useful at predicting the increased toxicity of drug combinations relative to the toxicity caused by the relevant single agent.
High-Throughput Analysis of DNA Samples using the D1K ScreenTape Assay and the Agilent 2200 TapeStation System
Agilent Technologies

Recent advances in genomics demands to look at a wealth of genetic information in a short period of time. DNA analysis using slab gel electrophoresis and capillary electrophoresis are widely being used as a QC step in next generation sequencing and microarray studies. However, often these techniques lack the speed and involve more manual steps to perform the assay.
Novel Antimalarial Drug Candidates Generated In Silico by Analysis of Public HTS Data
Simulations Plus

This research aims to provide proof-in-principle that in silico tools could be applied to public data so as to efficiently identify active chemistry with good ADMET properties.
Novel, Fully Automated Method Allows Efficient Analysis of qPCR Data for Qualitative Calling Based on Comparative Cq
Azure PCR Limited

Assessment to ascertain if a method for analysis of qPCR data dependent on manual intervention can be replaced by automated analysis using the AzurePCRTM method.
Application Notes
Performing ADCC Reporter Bioassay with an Environmentally Controlled Microplate Reader
Tecan Group Ltd.

The Promega ADCC Reporter Bioassay provides effector and target cells in frozen, thaw-and-use format, removing the need for isolating or culturing cells in order to perform the assay. Reporter induction requires a six-hour to overnight incubation in a standard cell culture incubator. The CO2 and temperature control features of the Tecan Infinite® 200 PRO with GCM allow the assay induction to be performed without the requirement for a cell culture incubator.
Sample preparation with the AC Extraction Plate: extraction of urinary THC metabolites for LC-MSMS quantification
Tecan Group Ltd.

In many countries, routine workplace drug testing involves screening for the free THC-COOH metabolite obtained by hydrolyzing THC-COOH glucuronide. Tecan’s AC Extraction Plate with TICE technology enables a straightforward workflow that is reproducible and cost efficient. Liquid chromatography coupled with tandem mass spectrometry (LC-MSMS) provides an easy and cost-effective means for fast, sensitive and precise analysis of THC and its metabolites.
Trends, Challenges and Strategy in the Forensic Science Sector
Netherlands Forensic Institute

The forensic science sector is in transition. New insights, technologies, and customers, combined with falling costs and increasing capabilities cause the sector to grow rapidly. As a consequence the role of forensic laboratories is changing.
The Analysis of Common Drugs of Abuse in an Oral Fluid Matrix using a New Q TRAP® Platform
AB SCIEX

The multiplexing analysis of several compound classes, such as common prescription drugs along with drugs of abuse is very important. The measurement of these drugs has generally been performed using urine as the sample matrix. However, many research laboratories are finding the need to analyze these compounds in oral fluid matrices.
Quantification of Ethylglucuronide in hair by Liquid Chromatography Tandem Mass Spectrometry
AB SCIEX

An advantage of the use of ethylglucuronide (ETG) in hair is that it is not subject to the effect of bacteria. It also offers the opportunity to extend the window of detection up to 6 months compared to hours- days in blood and urine.
Advanced Automated Library Searching for Compound Identification in Forensic Toxicology Samples
AB SCIEX

LC-MS/MS utilization in forensic toxicology screening for drugs and drug metabolites has become increasingly popular due to the selectivity, sensitivity and the speed of LC-MS/MS analysis. MS/MS confirmation with automated searching against available spectral libraries has proven to add a superior level of confidence to the compound identification.
A Complete Forensic Toxicology Screening Procedure for Drugs and Toxic Compounds in Urine and Plasma Using LC-MS/MS
Thermo Scientific

Implementation of liquid chromatography-mass spectrometry (LC-MS) for forensic toxicology screening provides specific and sensitive analysis of drugs and toxic substances.
Performance Evaluation of a Thermal Desorption System for Detection of Basic Drugs in Forensic Samples by GC/MS
GERSTEL Inc.

Stir bar sorptive extraction (SBSE) is an innovative sample extraction technique that can be used to process blood, urine, and tissue samples for routine drug screening in the forensic toxicology laboratory.
Toxicological Screening with the Agilent 6500 Series Accurate_mass Q-TOF LC/MS and personal Compound Database and Library using the Brorcker, Herre and Pragst Accurate Mass Spectral Library
Agilent Technologies

Screening using accurate mass measurement and a large database containing compounds of toxicological and forensic concern is possible with the Agilent Forensic Toxicology Personal Compound Database.
Toxtyper™ – a Comprehensive LC-MSn Screening Solution for Clinical and Forensic Toxicology
Bruker Corporation

In the clinic and the routine lab, fast and unambiguous identification of toxic compounds is the primary task. The screening solution presented here is based on ultrahigh performance liquid chromatography (UHPLC) coupled to an LC-MSn ion trap system.
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