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Saturday, December 20, 2014
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Mixtures Analysis of Complex Mixtures
Michael Bernstein; Carlos Cobas; Santi Domínguez; Manuel Pérez; Agustín Barba

We describe an NMR method to quantify mixture components in wine, edible oils, etc. The method is fully customizable, and amenable to high throughput operation.

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Isolation, Identification, and Determination of Designer Anabolic Steroids Commonly Found in Dietary Supplements
Sarah E. Voelker, M.S.; Travis M. Falconer, Ph.D.; Jonathan J. Litzau; Mary B. Jones; Lisa M. Lorenz

A general analytical approach in identifying emerging steroid-like compounds is presented, including analysis by GC-MS, LC-MS, and/or HPLC-UV. Isolation of unknown compounds was achieved by high performance liquid chromatography with fraction collection. Isolated compounds were characterized by Nuclear Magnetic Resonance spectroscopy and high resolution accurate mass-mass spectrometry to elucidate their structure.

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A Mass Spectrometer for Elemental Analysis based on Fieldable Technologies
Hilary Brown, Jennifer Speer, John Gerling, and Kenyon Evans-Nguyen

Laser ablation and a Microwave Plasma Torch (MPT) were coupled in order to obtain elemental information from solid samples. The MPT was incorporated as a less costly and more portable alternative to the ICP. MPT was also added to help improve the signal from just the laser ablation alone.

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High-Throughput Analysis of DNA Samples using the D1K ScreenTape Assay and the Agilent 2200 TapeStation System
Arunkumar Padmanaban, Ruediger Salowsky, Adam Inche

Recent advances in genomics demands to look at a wealth of genetic information in a short period of time. DNA analysis using slab gel electrophoresis and capillary electrophoresis are widely being used as a QC step in next generation sequencing and microarray studies. However, often these techniques lack the speed and involve more manual steps to perform the assay.

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Novel, Fully Automated Method Allows Efficient Analysis of qPCR Data for Qualitative Calling Based on Comparative Cq
Collaborative research by Pioneer Hi-Bred (a DuPont company) and Azure PCR Limited

Assessment to ascertain if a method for analysis of qPCR data dependent on manual intervention can be replaced by automated analysis using the AzurePCRTM method.

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An In Silico Test Battery for Rapid Evaluation of Genotoxic and Carcinogenic Potential of Chemicals
Kiril Lanevskij, Liutauras Juska, Justas Dapkunas, Andrius Sazonovas, Pranas Japertas and Remigijus Didziapetris, of ACD/Labs and Vilnius University

The FDA guidance for industry states impurities under the ICH threshold may be exaluated for genotoxicity and carcinogenicity. This study uses an expert system to detect mutagens and compounds labeled as potent carcinogens by the FDA.

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Rapid PCR for Integration in Sample-to-answer Analysis Platforms
S. Brunklaus, T.E. Hansen-Hagge, J. Erwes, J. Höth, M. Jung, D. Latta, X. Strobach, C. Winkler, T. Röser, M. Ritzi-Lehnert, K.S. Drese

This poster describes how molecular testing at the point-of-care can increase time to results and yield rather specific information, concentrating on PCR on a chip layout which proves to be fast and robust.

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Optical Microchip Sensors for Multiplexed Detection of Biological Pathogens
D. Bhatta, A. Michel, M. Marti Villalba, G. D. Emmerson, I. J. G Sparrow, M. B. McDonnell, E. A. Perkins , R. W. Ely and G. A. Cartwright

SpectroSens, a multi-channel optical microchip sensor system suitable for rapid, label-free multiplexed detection of a wide range of bio-hazardous agents is presented. Optical chips containing multiple high-precision planar Bragg gratings are exploited as low-cost, robust refractive index sensors.

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Showing Results 1 - 8 of 8
Scientific News
New Way to Analyze DNA Evidence Under Development
Forensic experts in crime labs around the world could soon have a new tool to help them better analyze DNA evidence thanks to the work of a Rutgers University–Camden computer scientist.
Identity of Richard III Confirmed
Analysis of all the available evidence confirms identity of King Richard III to the point of 99.999% (at its most conservative).
Stanford Engineers Discover How to Record the Forensic History of Chemical Contaminations in Water
An invention called a time capsule is a tiny chemistry lab designed to take a fingerprint of contamination and also disclose when it occurred.
Research to Assist Forensic Investigations
Grant will see OSU professor Dr Barry Lavine research the analysis of automobile paint samples to improve how forensic scientists track down vehicles in criminal investigations.
Making Sensor Technology Better at Bomb-Sniffing
University of Utah engineers have developed a new type of carbon nanotube material for handheld sensors that will be quicker and better at sniffing out explosives, deadly gases and illegal drugs.
Fruit Fly Could Help Sniff Out Drugs and Bombs
Research from the University of Sussex has found a fly’s sense of smell could be used in new technology to detect drugs and bombs.
Nanoparticles Give up Forensic Secrets
Researchers from Switzerland have thrown light on the precise mechanisms responsible for the impressive ability of nanoparticles to detect fingermarks left at crime scenes.
New Technique Yields Drug, Biomedical Test Results in One Minute
Slug flow microextraction makes it possible to quickly detect the presence of drugs or to monitor certain medical conditions using only a single drop of blood or urine.
Novel Method for Portable Detection of ‘Bath Salts’
Despite being outlawed in 2012 in the U.S., the synthetic drugs known as “bath salts” are still readily available in some retail shops, on the Internet and on the streets.
Mass Spectrometry in Your Hand
Electrospray arrays can dramatically downsize systems and costs for onsite chemical analysis and many other applications.
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