Corporate Banner
Satellite Banner
Forensic Science & Clinical Toxicology
Scientific Community
 
Become a Member | Sign in
Home>Resources>Application Notes>This Application Note
  Application Notes
Scientific News
Bringng NGS to the Crime Lab
New technology being validated in BCI lab for use in Ohio missing persons cases.
How Cloud Connectivity Can Combat the Reproducibility Crisis
This infographic explains the reproducibility crisis, and how cloud connectivity can help overcome this problem.
Detecting Drug Use in Hair
Scientists at Wageningen UR have developed a faster and more accurate method for the detection of drug use using hair.
Eliminating Doubt in Criminal Investigations
New ASU certificate to help curb error, misunderstanding in the quest for justice.
Determination of 13 Organic Toxicants in Human Blood
Researchers have utilised liquid-liquid extraction coupling HPLC-MS/MS to identify and quantify organic toxicants in human blood.
A Novel Cell Culture Model For Forensic Biology Experiments
Researchers have developed a new cell culture model which provides an efficient research tool in forensic biology.
Rhino DNA Bank Aids Anti-Poaching Fight
At the University of Pretoria's Veterinary Genetics Laboratory (VGL) at Onderstepoort, Dr Cindy Harper and her team have developed a ground-breaking technique to collect and catalogue DNA from rhinos and rhino horns.
Gender Determination in Forensic Investigations
This study investigated the effectiveness of lip print analysis as a tool in gender determination.
Identifying Novel Types of Forensic Markers in Degraded DNA
Scientists have tried to verify the nucleosome protection hypothesis by discovering STRs within nucleosome core regions, using whole genome sequencing.
ASMS 2016: Targeting Mass Spectrometry Tools for the Masses
The expanding application range of MS in life sciences, food, energy, and health sciences research was highlighted at this year's ASMS meeting in San Antonio, Texas.
Scroll Up
Scroll Down

Quantification of Ethylglucuronide in hair by Liquid Chromatography Tandem Mass Spectrometry
Bookmark and Share

SCIEX

Ethanol is converted to acetaldehyde and subsequently to acetic acid by liver enzymes. The traditional approach to assess the extent of alcohol consumption is through blood and urine analysis but unless the blood or urine samples are stored in appropriate specimen containers, with preservatives such as fluoride oxalate, ethanol can be produced as an artifact of bacterial fermentation post collection. This can result in elevated and hence inaccurate ethanol concentrations in these samples which can potentially affect the interpretation of any results obtained.

As ethanol metabolism is independent of dose, blood and urine concentrations can vary widely between individuals, however with hair analysis the use of a 30 pg/mg cut off, as proposed by the Society of Hair Testing (SoHT), can be applied as standard. 

This application note details a rapid, robust, sensitive and specific LC-MS/MS assay for the quantification of ETG, a marker for chronic excessive alcohol consumption, in hair, which has been developed in accordance with ISO17025 standards.

Further Information

Related Content

SCIEX Announces OneOmics™ Collaborators
Advaita Bioinformatics, Researchers at Yale University and ISB launch applications and libraries that combine next-generation proteomics and next-generation sequencing data in innovative ways.
Thursday, March 19, 2015
SCIEX and Labor Berlin Collaboration to Advance Forensic Testing
Collaboration for the development of a hybrid Quadrupole Time-of-Flight (TOF) MS/MS reference library.
Thursday, March 05, 2015
AB SCIEX Wins New Product Innovation Award in Asia Pacific
The award recognizes the company’s continued innovation in the mass spectrometry industry and a number of new products introduced into the market in recent years.
Thursday, October 30, 2014
AB SCIEX Expands in Singapore
AB SCIEX announce the next major phase of its expansion in Singapore, with the grand opening of a new R&D centre.
Friday, November 01, 2013
AB SCIEX Expands Support in the Middle East
AB SCIEX announces the opening of a new regional office and technical support centre located in Dubai.
Tuesday, October 29, 2013
AB SCIEX Receives Frost & Sullivan Award
AB SCIEX has been awarded the 2013 Global Market Share Leadership Award for Mass Spectrometry from Frost & Sullivan.
Thursday, September 12, 2013
Skyscraper Banner

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,300+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,900+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!