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 | Helping you to shape in vitro models with cell-based assays Christian Oberdanner, Ph.D. Marketing Application Specialist Detection for Tecan Austria |
 | Comprehensive microRNA Expression Profiling in Lineage Specific Human Hematopoiesis Nalini Raghavachari, NIH, speaking at Genomics Research 2013. |
qPCR Assay Trends 2013
HTStec
HTStec's qPCR Assay Trends 2013 report was published on 15 April 2013. This 63 page market report summarizes the results of HTStec's 3rd industry-wide global web-based benchmarking survey on real-time quantitative PCR (qPCR) assays and instruments carried out in March 2013.
Circulating Tumor Cells (CTCs) and Cancer Stem Cells (CSCs) Market Report 2013
Select Biosciences Ltd
This is the latest and most up-to-date Market Report from Select Biosciences addressing the CTC and CSC markets as they are evolving rapidly.
Benchtop Automation Trends 2013
HTStec
This market report summarizes the results of HTStec's industry-wide global web-based benchmarking survey on small-scale or benchtop automation carried out in January 2013.
CTC Technologies
RI Technologies
This report on Circulating Tumor Cells (CTC) Technologies gives a market insight into technologies and services used for cancer detection.
RNA Therapeutics Pipeline Database
La Merie
Subscription to La Merie’s proprietary RNA Therapeutics Pipeline Database provides online access to RNA Therapeutics on the market and in research & development.
Genetic Testing Reagents - Global Pipeline Analysis, Competitive Landscape and Market Forecasts to 2017
GlobalData
The report provides key data, information and analysis on the global genetic testing market. The report provides market landscape, competitive landscape and market trends information on the genetic testing market. The report provides comprehensive information on the key trends affecting the market, and key analytical content on the market dynamics. The report also reviews the competitive landscape and technology offerings.
Epigenetic Screening Trends
HTStec
This market report summarizes the results of HTStec’s 2nd industry-wide global web-based benchmarking survey on epigenetic screening assays carried out in May 2012.
Next Generation Sequencing (NGS) Market
MarketsandMarkets
by technology (pyrosequencing & others), competitors (Illumina, 454 Roche, Life Science Technologies), applications & tools - global trends & forecasts (2011 – 2016)
Life Science and Chemical Instrumentation Market (2011 - 2016)
MarketsandMarkets
Spectroscopy, Chromatography, DNA Sequencer & Amplifier, Lab Automation, Array, Flow Cytometer, Electrophoresis, Immuno Assay & Others
Personalized Medicine Market - Advances in Human Genomics and Proteomics to Challenge Traditional Therapeutics
GBI Research
The report provides key data, information and analysis of the major trends and issues in Personalized Medicine Market. The report provides a comprehensive insight into the role of Human Genomics and Proteomics to challenge traditional therapeutics.
HTStec
HTStec's qPCR Assay Trends 2013 report was published on 15 April 2013. This 63 page market report summarizes the results of HTStec's 3rd industry-wide global web-based benchmarking survey on real-time quantitative PCR (qPCR) assays and instruments carried out in March 2013.
Circulating Tumor Cells (CTCs) and Cancer Stem Cells (CSCs) Market Report 2013
Select Biosciences Ltd
This is the latest and most up-to-date Market Report from Select Biosciences addressing the CTC and CSC markets as they are evolving rapidly.
Benchtop Automation Trends 2013
HTStec
This market report summarizes the results of HTStec's industry-wide global web-based benchmarking survey on small-scale or benchtop automation carried out in January 2013.
CTC Technologies
RI Technologies
This report on Circulating Tumor Cells (CTC) Technologies gives a market insight into technologies and services used for cancer detection.
RNA Therapeutics Pipeline Database
La Merie
Subscription to La Merie’s proprietary RNA Therapeutics Pipeline Database provides online access to RNA Therapeutics on the market and in research & development.
Genetic Testing Reagents - Global Pipeline Analysis, Competitive Landscape and Market Forecasts to 2017
GlobalData
The report provides key data, information and analysis on the global genetic testing market. The report provides market landscape, competitive landscape and market trends information on the genetic testing market. The report provides comprehensive information on the key trends affecting the market, and key analytical content on the market dynamics. The report also reviews the competitive landscape and technology offerings.
Epigenetic Screening Trends
HTStec
This market report summarizes the results of HTStec’s 2nd industry-wide global web-based benchmarking survey on epigenetic screening assays carried out in May 2012.
Next Generation Sequencing (NGS) Market
MarketsandMarkets
by technology (pyrosequencing & others), competitors (Illumina, 454 Roche, Life Science Technologies), applications & tools - global trends & forecasts (2011 – 2016)
Life Science and Chemical Instrumentation Market (2011 - 2016)
MarketsandMarkets
Spectroscopy, Chromatography, DNA Sequencer & Amplifier, Lab Automation, Array, Flow Cytometer, Electrophoresis, Immuno Assay & Others
Personalized Medicine Market - Advances in Human Genomics and Proteomics to Challenge Traditional Therapeutics
GBI Research
The report provides key data, information and analysis of the major trends and issues in Personalized Medicine Market. The report provides a comprehensive insight into the role of Human Genomics and Proteomics to challenge traditional therapeutics.
Expelled DNA that Traps Toxins May Backfire in Obese
The body’s most powerful immune cells may have a radical way of catching their prey that could backfire on people who are overweight.
Developing Cancer Drugs
Researchers find therapeutic potential in ‘undruggable’ target.
Aspirin May Fight Cancer by Slowing DNA Damage
UCSF-led study of patients with pre-cancerous conditions probed NSAID effects on mutation rate.
Precocious Puberty Gene Found
Broad Institute scientists have discovered a gene which causes some cases of early-onset puberty.
Developmental Protein Plays Role in Spread of Cancer
A protein used by embryo cells during early development, and recently found in many different types of cancer, apparently serves as a switch regulating metastasis.
Bringing Out the Usual – and Unusual – Cancer Genomics Suspects
Several years ago, researchers sequencing lung cancer genomes encountered a number of red herrings.
Yale Researchers Unravel Genetics of Dyslexia and Language Impairment
A new study of the genetic origins of dyslexia and other learning disabilities could allow for earlier diagnoses and more successful interventions.
Circuitry of Cells Involved in Immunity, Autoimmune Diseases Exposed
Connections point to interplay between salt and genetic factors.
Two Gene Variants May Predict Who Will Benefit from Breast Cancer Prevention Drugs
NIH-supported discovery could advance individualized care of high-risk women.
Supreme Court Rules That Human Genes Can’t Be Patented
Most agree that the ruling reduces barriers to genetic testing and enables scientists to further genetic research and share data aimed ultimately at preventing and curing disease.
The body’s most powerful immune cells may have a radical way of catching their prey that could backfire on people who are overweight.
Developing Cancer Drugs
Researchers find therapeutic potential in ‘undruggable’ target.
Aspirin May Fight Cancer by Slowing DNA Damage
UCSF-led study of patients with pre-cancerous conditions probed NSAID effects on mutation rate.
Precocious Puberty Gene Found
Broad Institute scientists have discovered a gene which causes some cases of early-onset puberty.
Developmental Protein Plays Role in Spread of Cancer
A protein used by embryo cells during early development, and recently found in many different types of cancer, apparently serves as a switch regulating metastasis.
Bringing Out the Usual – and Unusual – Cancer Genomics Suspects
Several years ago, researchers sequencing lung cancer genomes encountered a number of red herrings.
Yale Researchers Unravel Genetics of Dyslexia and Language Impairment
A new study of the genetic origins of dyslexia and other learning disabilities could allow for earlier diagnoses and more successful interventions.
Circuitry of Cells Involved in Immunity, Autoimmune Diseases Exposed
Connections point to interplay between salt and genetic factors.
Two Gene Variants May Predict Who Will Benefit from Breast Cancer Prevention Drugs
NIH-supported discovery could advance individualized care of high-risk women.
Supreme Court Rules That Human Genes Can’t Be Patented
Most agree that the ruling reduces barriers to genetic testing and enables scientists to further genetic research and share data aimed ultimately at preventing and curing disease.
Genmab and ADC Therapeutics Enter Co-Development Collaboration
Combines strength of HuMax®-TAC with next generation PBD-based warhead technology.
Aragon Pharmaceuticals Announces Acquisition by Johnson & Johnson
Aragon to spin off new corporation, Seragon Pharmaceuticals, focused on Selective Estrogen Receptor Degrader Platform.
Rexahn Awarded U.S. Patent for Novel Anti-Cancer Compounds
Company announced that it has significantly expanded its intellectual property around a series of novel anti-tumor quinazoline compounds.
Curie-Cancer and Sanofi Cooperate in Research on Ovarian Cancer
Preclinical program of translational research tasked with identifying new target proteins.
UroSens Receives Funding and Enters into Clinical Trials
Board of directors strengthened with key appointments.
Horizon Establishes Two New Centers of Excellence in Cambridge, UK
Leading researchers Steve Jackson and David Rubinsztein to apply rAAV gene editing technology in studies of oncology and neurodegenerative disease.
Proteome Sciences to Develop Cancer Pathway Profiling Assays
New MS3 TMT® mass spectrometry technique to determine relative quantitation of proteins in multiple samples simultaneously.
Source BioScience Launches New Overnight Service for DNA Sequencing
Overnight service offers free sample collection and rapid delivery of results in Scotland.
apceth Receives Approval for a Clinical Cancer Trial with Adult Mesenchymal Stem Cells
apceth's first innovative cellular anti-cancer drug based on modified mesenchymal stem cells enters Phase I / II of clinical testing.
Genomic Vision to Extend its Strategic R&D Alliance with Quest Diagnostics
Quest Diagnostics will invest in the planned development of a lab-developed test.
Combines strength of HuMax®-TAC with next generation PBD-based warhead technology.
Aragon Pharmaceuticals Announces Acquisition by Johnson & Johnson
Aragon to spin off new corporation, Seragon Pharmaceuticals, focused on Selective Estrogen Receptor Degrader Platform.
Rexahn Awarded U.S. Patent for Novel Anti-Cancer Compounds
Company announced that it has significantly expanded its intellectual property around a series of novel anti-tumor quinazoline compounds.
Curie-Cancer and Sanofi Cooperate in Research on Ovarian Cancer
Preclinical program of translational research tasked with identifying new target proteins.
UroSens Receives Funding and Enters into Clinical Trials
Board of directors strengthened with key appointments.
Horizon Establishes Two New Centers of Excellence in Cambridge, UK
Leading researchers Steve Jackson and David Rubinsztein to apply rAAV gene editing technology in studies of oncology and neurodegenerative disease.
Proteome Sciences to Develop Cancer Pathway Profiling Assays
New MS3 TMT® mass spectrometry technique to determine relative quantitation of proteins in multiple samples simultaneously.
Source BioScience Launches New Overnight Service for DNA Sequencing
Overnight service offers free sample collection and rapid delivery of results in Scotland.
apceth Receives Approval for a Clinical Cancer Trial with Adult Mesenchymal Stem Cells
apceth's first innovative cellular anti-cancer drug based on modified mesenchymal stem cells enters Phase I / II of clinical testing.
Genomic Vision to Extend its Strategic R&D Alliance with Quest Diagnostics
Quest Diagnostics will invest in the planned development of a lab-developed test.
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Oral Health Management of a Patient with 47 XYY Syndrome
College of Dentistry, Salman bin Abdulaziz University
The 47XYY syndrome is an aneuploidy of sex chromosomes, where a human male receives an extra Y-chromosome making a total of 47 instead of the usual 46.
The Challenges of Relieving Cancer Pain: A Literature Review
NHS
This study aims to explore the discrepancy between the increasing array of treatments for cancer pain, as well as the evidence that it can be managed effectively in the majority of cases, and its persisting prevalence.
Evaluation of 2012 Bowel Cancer Awareness and Early Diagnosis Campaign at a District General Hospital
Brighton and Sussex University Hospitals
Following the regional Be Clear on Cancer campaign, the Department of Health launched a national bowel cancer awareness campaign from 30 January 2012. The campaign ran until the end of March.
Identification and Characterization of Strain Specific Drug Target by Subtractive Genome Analysis of Methicillin Resistance Staphylococcus aureus
University of Karachi
This study aimed to identify and characterize strain specific essential protein targets, which will eventually help in the identification of druggable proteins in two strains of MRSA by using different Bioinformatic tools and databases. We adopting a subtractive genome approach within the domain of Computational Biology.
Kidney Genes Expression in Hypertensive ISIAH Rats
ICIH SO RAN
The present study was performed to detect the key genes involved in the hypertensive phenotype manifestation in the ISIAH rats with inherited stress-induced arterial hypertension.
Automated Genomic DNA QC Ensures High Quality Data from Downstream Workflows
Agilent Technologies
The success of several genomics study depends primarily on the quality of starting material, which in most cases is the genomic DNA. The quality and quantity of the extracted genomic DNA affects the downstream applications like microarray studies, library constructions and gene expression studies.
High-Throughput Analysis of DNA Samples using the D1K ScreenTape Assay and the Agilent 2200 TapeStation System
Agilent Technologies
Recent advances in genomics demands to look at a wealth of genetic information in a short period of time. DNA analysis using slab gel electrophoresis and capillary electrophoresis are widely being used as a QC step in next generation sequencing and microarray studies. However, often these techniques lack the speed and involve more manual steps to perform the assay.
FDG PET/CT Utility in Gynecologic Malignancies: A comprehensive review of anatomy, pathways of metastatic spread and scan findings
Emory University Hospital
Our objective was to review the five major gynaecologic cancers (cervical, ovarian, uterine, vaginal, and vulvar) and demonstrate the role of FDG PET/CT in diagnosis, surveillance, FIGO staging and treatment strategy.
FDG PET/CT Characteristics of Adrenal Benign and Malignant Lesions
Emory University Hospital
We selected FDG PET/CT cases with strong key representative findings to help illustrate benign and malignant adrenal lesions. Tabular review of PET SUV values, Hounsfield units and lesion size in the different cases will be discussed.
Hot Start dNTPs – Pushing the Limits of PCR
Agilent Technologies
Hot Start dNTPs are a distinct approach that employs modified nucleoside triphosphates with a thermolabile protecting group. This modification blocks low temperature primer extension and is released at higher temperatures to allow for more specific DNA polymerase incorporation.
College of Dentistry, Salman bin Abdulaziz University
The 47XYY syndrome is an aneuploidy of sex chromosomes, where a human male receives an extra Y-chromosome making a total of 47 instead of the usual 46.
The Challenges of Relieving Cancer Pain: A Literature Review
NHS
This study aims to explore the discrepancy between the increasing array of treatments for cancer pain, as well as the evidence that it can be managed effectively in the majority of cases, and its persisting prevalence.
Evaluation of 2012 Bowel Cancer Awareness and Early Diagnosis Campaign at a District General Hospital
Brighton and Sussex University Hospitals
Following the regional Be Clear on Cancer campaign, the Department of Health launched a national bowel cancer awareness campaign from 30 January 2012. The campaign ran until the end of March.
Identification and Characterization of Strain Specific Drug Target by Subtractive Genome Analysis of Methicillin Resistance Staphylococcus aureus
University of Karachi
This study aimed to identify and characterize strain specific essential protein targets, which will eventually help in the identification of druggable proteins in two strains of MRSA by using different Bioinformatic tools and databases. We adopting a subtractive genome approach within the domain of Computational Biology.
Kidney Genes Expression in Hypertensive ISIAH Rats
ICIH SO RAN
The present study was performed to detect the key genes involved in the hypertensive phenotype manifestation in the ISIAH rats with inherited stress-induced arterial hypertension.
Automated Genomic DNA QC Ensures High Quality Data from Downstream Workflows
Agilent Technologies
The success of several genomics study depends primarily on the quality of starting material, which in most cases is the genomic DNA. The quality and quantity of the extracted genomic DNA affects the downstream applications like microarray studies, library constructions and gene expression studies.
High-Throughput Analysis of DNA Samples using the D1K ScreenTape Assay and the Agilent 2200 TapeStation System
Agilent Technologies
Recent advances in genomics demands to look at a wealth of genetic information in a short period of time. DNA analysis using slab gel electrophoresis and capillary electrophoresis are widely being used as a QC step in next generation sequencing and microarray studies. However, often these techniques lack the speed and involve more manual steps to perform the assay.
FDG PET/CT Utility in Gynecologic Malignancies: A comprehensive review of anatomy, pathways of metastatic spread and scan findings
Emory University Hospital
Our objective was to review the five major gynaecologic cancers (cervical, ovarian, uterine, vaginal, and vulvar) and demonstrate the role of FDG PET/CT in diagnosis, surveillance, FIGO staging and treatment strategy.
FDG PET/CT Characteristics of Adrenal Benign and Malignant Lesions
Emory University Hospital
We selected FDG PET/CT cases with strong key representative findings to help illustrate benign and malignant adrenal lesions. Tabular review of PET SUV values, Hounsfield units and lesion size in the different cases will be discussed.
Hot Start dNTPs – Pushing the Limits of PCR
Agilent Technologies
Hot Start dNTPs are a distinct approach that employs modified nucleoside triphosphates with a thermolabile protecting group. This modification blocks low temperature primer extension and is released at higher temperatures to allow for more specific DNA polymerase incorporation.
Molecular indexing for improved RNA-Seq analysis
Bioo Scientific
Most modern methods for nucleic acid analysis require the use of enzyme processing, such as DNA polymerase reactions, in the sample preparation or measurement steps. Although necessary, these enzymatic steps introduce errors in the form of incorrect sequence and misrepresented copy number. NEXTflex™ qRNA-Seq™ Kit from Bioo Scientific adds no additional steps to the work flow, costs no more than a conventional library preparation kit and increases the precision of downstream analysis.
An Integrated Solution to Simplify Library Preparation and Multiplexing for NimbleGen Sequence Capture
Bioo Scientific
The studies described herein demonstrate the capability of Bioo Scientific’s novel NEXTFlex™ DNA Pre-Capture Combo Library construction kits used in conjunction with the NimbleGen Sequence Capture technology to obtain high coverage comparative genomic data from a panel of human HapMap DNA samples.
BRD4 Bromodomain 1 Inhibitor Screening Using a Homogeneous Proximity Assay
BioTek Instruments
Demonstration of profiling and primary screening of an epigenetic target; a histone acetylating bromodomain. This is a TR-FRET based application highlighting the use of automated instrumentation and a high-throughput screening (HTS) multi-mode microplate reader.
Integration of Liquid Handler Quality Control Into the HTS Daily Routine
Artel
This application note describes how the Artel MVS® Multichannel Verification System can be used to assess the performance of the liquid handlers integrated into a PerkinElmer cell::explorer high throughput screening (HTS) system.
Purification of Genomic DNA from Saliva Using Oragene® Discover Collection Kits and the Akonni TruTip® Extraction System on the Hamilton Microlab® STAR Liquid Handling Workstation
Hamilton
In the following studies, we have demonstrated the high precision of the automated TruTip extraction technology in processing genomic DNA from low-volume saliva samples and its advantage over competitors.
Rapid, High Throughput Extraction and Purification of Genomic DNA from Whole Blood Using the Akonni TruTip® Extraction System on the Hamilton Microlab® STAR Liquid Handling System
Hamilton
This application note demonstrates the high precision of the automated extraction system in processing genomic DNA from low volume whole blood samples and its advantage over competitors.
Next Generation Sequencing Method for Illumina TruSeq DNA Sample Preparation Protocol on the Hamilton STAR
Hamilton
The purpose of the TruSeq sample preparation protocol is to add adapter sequences onto the ends of DNA fragments to generate multiplexed sequencing libraries. Good liquid handling is crucial for pipetting precise volumes for example for Agilent Bioanalyzer.
Automating Aqueous Compound Solubility Using the 96-Well Multiscreen® Solubility Filter Plate on a Hamilton Microlab® Star Workstation
Hamilton
Here we describe an automated method for determining drug solubility using Millipore’s MultiScreen Solubility filter plate on the Hamilton MICROLAB STAR workstation.
Automated GS FLX Titanium emPCR Enrichment using the REM e System on a Hamilton Microlab® STARlet Liquid Handler
Hamilton
The Genome Sequencer FLX System is a versatile sequencing platform suitable for a wide range of research applications, including de novo sequencing and assembly of genomic DNA, transcriptome sequencing, small RNA analysis, and amplicon sequencing.
Automated Liquid-liquid Extraction of 25-Hydroxy Vitamin D from Serum and Preparation for LC/MC Analysis Using the Hamilton Robotics Microlab STARlet Workstation
Hamilton
This application note demonstrates the automation capabilities of Hamilton Robotics’ Microlab STARlet and how it can be used to prepare clinical serum samples for Vitamin D analysis quickly, reliably and cost effectively.
Bioo Scientific
Most modern methods for nucleic acid analysis require the use of enzyme processing, such as DNA polymerase reactions, in the sample preparation or measurement steps. Although necessary, these enzymatic steps introduce errors in the form of incorrect sequence and misrepresented copy number. NEXTflex™ qRNA-Seq™ Kit from Bioo Scientific adds no additional steps to the work flow, costs no more than a conventional library preparation kit and increases the precision of downstream analysis.
An Integrated Solution to Simplify Library Preparation and Multiplexing for NimbleGen Sequence Capture
Bioo Scientific
The studies described herein demonstrate the capability of Bioo Scientific’s novel NEXTFlex™ DNA Pre-Capture Combo Library construction kits used in conjunction with the NimbleGen Sequence Capture technology to obtain high coverage comparative genomic data from a panel of human HapMap DNA samples.
BRD4 Bromodomain 1 Inhibitor Screening Using a Homogeneous Proximity Assay
BioTek Instruments
Demonstration of profiling and primary screening of an epigenetic target; a histone acetylating bromodomain. This is a TR-FRET based application highlighting the use of automated instrumentation and a high-throughput screening (HTS) multi-mode microplate reader.
Integration of Liquid Handler Quality Control Into the HTS Daily Routine
Artel
This application note describes how the Artel MVS® Multichannel Verification System can be used to assess the performance of the liquid handlers integrated into a PerkinElmer cell::explorer high throughput screening (HTS) system.
Purification of Genomic DNA from Saliva Using Oragene® Discover Collection Kits and the Akonni TruTip® Extraction System on the Hamilton Microlab® STAR Liquid Handling Workstation
Hamilton
In the following studies, we have demonstrated the high precision of the automated TruTip extraction technology in processing genomic DNA from low-volume saliva samples and its advantage over competitors.
Rapid, High Throughput Extraction and Purification of Genomic DNA from Whole Blood Using the Akonni TruTip® Extraction System on the Hamilton Microlab® STAR Liquid Handling System
Hamilton
This application note demonstrates the high precision of the automated extraction system in processing genomic DNA from low volume whole blood samples and its advantage over competitors.
Next Generation Sequencing Method for Illumina TruSeq DNA Sample Preparation Protocol on the Hamilton STAR
Hamilton
The purpose of the TruSeq sample preparation protocol is to add adapter sequences onto the ends of DNA fragments to generate multiplexed sequencing libraries. Good liquid handling is crucial for pipetting precise volumes for example for Agilent Bioanalyzer.
Automating Aqueous Compound Solubility Using the 96-Well Multiscreen® Solubility Filter Plate on a Hamilton Microlab® Star Workstation
Hamilton
Here we describe an automated method for determining drug solubility using Millipore’s MultiScreen Solubility filter plate on the Hamilton MICROLAB STAR workstation.
Automated GS FLX Titanium emPCR Enrichment using the REM e System on a Hamilton Microlab® STARlet Liquid Handler
Hamilton
The Genome Sequencer FLX System is a versatile sequencing platform suitable for a wide range of research applications, including de novo sequencing and assembly of genomic DNA, transcriptome sequencing, small RNA analysis, and amplicon sequencing.
Automated Liquid-liquid Extraction of 25-Hydroxy Vitamin D from Serum and Preparation for LC/MC Analysis Using the Hamilton Robotics Microlab STARlet Workstation
Hamilton
This application note demonstrates the automation capabilities of Hamilton Robotics’ Microlab STARlet and how it can be used to prepare clinical serum samples for Vitamin D analysis quickly, reliably and cost effectively.
