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  Events - December 2012


4th World Epigenetics Summit

04 Dec 2012 - 06 Dec 2012 - London, UK



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The 4th World Epigenetics Summit provides a unique platform on which senior representatives from GSK, Constellation and Epizyme share ideas with leading academic figures such as Tony Kouzarides and Chas Bountra. In bringing together the minds behind the most exciting drugs in development, the meeting represents two days dedicated to overcoming the most pressing challenges in epigenetic drug development.

Why attend?

Get an up-to-the-minute snapshot of the very latest epigenetic target classes for disease therapy from Epizyme, GSK and Constellation Pharmaceuticals

 Learn how the SGC are driving innovation by open source chemical probe design

 Discover the excitement that epigenetic drugs are generating in the clinic with 4SC

 Explore the potential of epigenetic modulation in non-oncological disease indications with GSK

Get excited at the potential of RNA therapeutics in a range of disease indications with RaNA Therapeutics

Find out how to optimize methods, assays and practices throughout the production pipeline so you can maximize the value of your R&D spend




Further information
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The Genetic Roots of Adolescent Scoliosis
Scientists at the RIKEN Center for Integrative Medical Sciences in collaboration with Keio University in Japan have discovered a gene that is linked to susceptibility of Scoliosis.
A Gene-Sequence Swap Using CRISPR to Cure Haemophilia
For the first time chromosomal defects responsible for hemophilia have been corrected in patient-specific iPSCs using CRISPR-Cas9 nucleases
New Tool Uses 'Drug Spillover' to Match Cancer Patients with Treatments
Researchers have developed a new tool that improves the ability to match drugs to disease: the Kinase Addiction Ranker (KAR) predicts what genetics are truly driving the cancer in any population of cells and chooses the best "kinase inhibitor" to silence these dangerous genetic causes of disease.
Understanding the Molecular Origin of Epigenetic Markers
Researchers at IRB Barcelona discover the molecular mechanism that determines how epigenetic markers influence gene expression.
New Tech Enables Epigenomic Analysis with a Mere 100 Cells
A new technology that will dramatically enhance investigations of epigenomes, the machinery that turns on and off genes and a very prominent field of study in diseases such as stem cell differentiation, inflammation and cancer has been developed by researchers at Virginia Tech.
Access Denied: Leukemia Thwarted by Cutting Off Link to Environmental Support
A new study reveals a protein’s critical – and previously unknown -- role in the development and progression of acute myeloid leukemia (AML), a fast-growing and extremely difficult-to-treat blood cancer.
New Weapon in the Fight Against Blood Cancer
This strategy, which uses patients’ own immune cells, genetically engineered to target tumors, has shown significant success against multiple myeloma, a cancer of the plasma cells that is largely incurable.
Toxin from Salmonid Fish has Potential to Treat Cancer
Researchers from the University of Freiburg decode molecular mechanism of fish pathogen.
Study Finds Non-Genetic Cancer Mechanism
Cancer can be caused solely by protein imbalances within cells, a study of ovarian cancer has found.
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