Corporate Banner
Satellite Banner
Scientific Community
Become a Member | Sign in
Home>News>This Article

Hamilton Robotics and French Police Scientifique Publish Paper Describing Large-Scale Production of Genetic Profiles

Published: Wednesday, March 10, 2010
Last Updated: Wednesday, March 10, 2010
Bookmark and Share
More than 300,000 profiles have already been processed on the Hamilton platforms and stored in French Database.

Scientists from Hamilton Robotics and Institut National de la Police Scientifique in Lyon, France have published an article in the December issue of Forensic Science International describing the protocols and three-year track record of a large-scale system they developed.

The automated system has processed in duplicate and deposited more than 300,000 genotypes into the French Reference Sample Database. The system produces genetic profiles from buccal swab cells on FTA* cards. Initially designed to process 20,000 samples per month, the system’s capacity was recently doubled to 40,000 per month without adding hardware.  

The samples on FTA cards are punched directly into PCR plates and transferred onto the Hamilton MICROLAB® STAR liquid handling workstation. The Hamilton air displacement pipetting and CO-RE (Compressed O-Ring Expansion) technology ensure contamination-free FTA wash and PCR reaction setup. Microplates are then sealed and transferred to a post-PCR system for pooling into a 384-well format and denaturing. Samples are tracked throughout the process and data is transferred to a LIMS.

“This is one of the first large-scale automated systems for forensic DNA analysis with a demonstrable track record,” explained Laurent Baron Product Manager Forensics, of Hamilton. “The creation of genetic databases requires highly reliable and robust automation, which our air displacement technology makes possible.”

Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,800+ scientific posters on ePosters
  • More than 4,000+ scientific videos on LabTube
  • 35 community eNewsletters

Sign In

Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Automation of Adherent Cell Culture Maintenance
Hamilton, Life & Brain and University of Bonn will jointly develop a system for the automated culture of primary cells, cell lines and embryonic stem cells.
Monday, May 14, 2007
Scientific News
New Class of RNA Tumor Suppressors Identified
Two short, “housekeeping” RNA molecules block cancer growth by binding to an important cancer-associated protein called KRAS. More than a quarter of all human cancers are missing these RNAs.
Biologists Induce Flatworms to Grow Heads and Brains of Other Species
Findings shed light on role of a new kind of epigenetic signaling in evolution, could yield clues for understanding birth defects and regeneration.
Turning up the Tap on Microbes Leads to Better Protein Patenting
Mining millions of proteins could become faster and easier with a new technique that may also transform the enzyme-catalyst industry, according to University of California, Davis, researchers.
Mathematical Model Forecasts the Path of Breast Cancer
Chances of survival depend on which organs breast cancer tumors colonize first.
Exploring the Causes of Cancer
Queen's research to understand the regulation of a cell surface protein involved in cancer.
Ancient Viral Molecules Essential for Human Development
Genetic material from ancient viral infections is critical to human development, according to researchers at the Stanford University School of Medicine.
Tardigrade's Are DNA Master Thieves
Tardigrades, nearly microscopic animals that can survive the harshest of environments, including outer space, hold the record for the animal that has the most foreign DNA.
The Secret Behind the Power of Bacterial Sex
Migration between different communities of bacteria is the key to the type of gene transfer that can lead to the spread of traits such as antibiotic resistance, according to researchers at Oxford University.
Farming’s in Their DNA
Ancient genomes reveal natural selection in action.
GMO Food Animals Should be Judged by Product, Not Process
In a world with a burgeoning demand for meat, milk and eggs, regulatory policies around the use of biotechnologies in agriculture need to be based on the safety and attributes of those foods rather than on the methods used to produce them, says a UC Davis animal scientist.
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,800+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,000+ scientific videos