Corporate Banner
Satellite Banner
Genomics
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

NSF Funds Research Partnership Between Bioo Scientific and Mirna Therapeutics

Published: Thursday, July 22, 2010
Last Updated: Thursday, July 22, 2010
Bookmark and Share
The funding will support tumor regression and pharmacokinetic studies on targeted delivery of microRNAs.

Bioo Scientific Corporation announced today that it has been awarded an additional $100,000 for its Small Business Innovation Research (SBIR) Phase II grant from the National Science Foundation.

The funding will support tumor regression and pharmacokinetic studies featuring escalating doses of a microRNA-based therapeutic candidate from Mirna Therapeutics, Inc., used in combination with Bioo Scientific’s targeted transport technology. The supplemental funding brings the total financial support for this phase of the NSF project to $600,000.

The targeted transport technology (T3) combines a positively charged carrier compound and an antibody that is specific to a cell surface receptor to directly deliver RNA-interfering (RNAi) mediator payloads to specific cells in the body. The carrier-antibody conjugate, loaded with an RNAi mediator, can be administered systemically or locally to an animal (or cultured cells) where it is internalized by cells bearing surface receptors that are targeted by the antibody. Upon cell entry, the RNAi mediator is released from the T3 delivery vehicle and allowed to silence the expression of its intended targets. Bioo Scientific has been expanding its collection of antibody carrier controls and recently launched a conjugation kit to enable customers to develop antibody delivery vehicles in their own laboratories.

The RNAi mediator provided by Mirna Therapeutics is a mimic of the potent tumor suppressor microRNA, miR-34, which has proven to be effective and safe when used in animal models of cancer. miR-34 is a key component of the p53 tumor suppressor pathway and is responsible for regulating multiple cancer-related genes and cellular processes.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,900+ scientific posters on ePosters
  • More than 4,200+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Bioo Scientific Awarded $750,000 NSF Grant
Company awarded a National Science Foundation Phase II grant to continue development efforts to improve the accuracy of small RNA expression analysis.
Wednesday, November 26, 2014
Bioo Scientific Receives Presidential Award for Exports
Awards are the highest recognition any U.S. entity may receive for making a significant contribution to the expansion of U.S. exports.
Thursday, May 29, 2014
Bioo Scientific Awarded SBIR Grant for Development of Targeted RNAi In Vivo Delivery Technology
A $500,000 Phase II grant will help to develop kits and reagents based on the patent-pending Targeted Transport Technology.
Wednesday, July 29, 2009
Bioo Scientific Corp. Receives NIH Grant for the Development of Novel Anti-Viral Therapeutics
Researchers discover a mechanism by which several viruses suppress aspects of the cell to stabilize their nucleic acids to promote an efficient infection.
Tuesday, May 05, 2009
Custom RNA Interference Service
BIOO Scientific is launching a service to perform in vivo RNAi testing to facilitate progress in the drug pipeline.
Thursday, April 12, 2007
Scientific News
NIH Researchers Identify Striking Genomic Signature for Cancer
Institute has identified striking signature shared by five types of cancer.
CRI Develops Innovative Approach for Identifying Lung Cancer
Institute has developed innovative approach for identifying processes that fuel tumor growth in lung cancer patients.
The Spice of Life
Scientists discover important genetic source of human diversity.
Removing Race from Human Genetic Research
A group of scientists are urging their colleagues to take a step forward and stop using racial categories when researching and studying human genetics.
Tick Genome Reveals Secrets of a Successful Bloodsucker
NIH-funded study could lead to new tick control methods.
Light Signals from Living Cells
Fluorescent protein markers delivered under high pressure.
Counting Cancer-busting Oxygen Molecules
Researchers from the Centre for Nanoscale BioPhotonics (CNBP), an Australian Research Centre of Excellence, have shown that nanoparticles used in combination with X-rays, are a viable method for killing cancer cells deep within the living body.
Genomic Signature Shared by Five Types of Cancer
National Institutes of Health researchers have identified a striking signature in tumor DNA that occurs in five different types of cancer.
Crowdfunding the Fight Against Cancer
From budding social causes to groundbreaking businesses to the next big band, crowdfunding has helped connect countless worthy projects with like-minded people willing to support their efforts, even in small ways. But could crowdfunding help fight cancer?
Switch Lets Salmonella Fight, Evade Immune System
Researchers at the University of Illinois at Chicago have discovered a molecular regulator that allows salmonella bacteria to switch from actively causing disease to lurking in a chronic but asymptomatic state called a biofilm.
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,900+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,200+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!