Corporate Banner
Satellite Banner
Genomics
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

IDT Launches xGen™ Lockdown™ Probes

Published: Thursday, September 06, 2012
Last Updated: Thursday, September 06, 2012
Bookmark and Share
Scalable target capture probes for Next Generation Sequencing.

Integrated DNA Technologies (IDT), the world leader in oligonucleotide synthesis, now provides xGen™ Lockdown™ Probes individually synthesized 60-120 nucleotide 5’-biotinylated capture oligonucleotides designed to enable cost-effective, high depth sequencing and analysis of specific regions of the genome.

xGen Lockdown Probes are ideal for target enrichment and custom panel development, and capture sets can be easily expanded. Available at three different scales (mini – 2 pmole, standard – 20 pmole, and XL – 200 pmole), users can design their initial capture panels using the mini scale and extend them by progressively supplementing with more probes. As a result, it is quick and simple to transition to higher volume applications.

Whether used with custom capture panels, or for supplementing existing panels, xGen Lockdown Probes provide approximately 5000-fold enrichment with high coverage over targeted regions, and minimal GC bias. Furthermore, the probes can be added to array-derived RNA baits to enhance coverage of GC-rich targets, such as first exons. Users can therefore improve capture performance by rescuing drop-out regions of array-derived exome capture, improve the uniformity of coverage, discover additional genetic mutations, or improve coverage of specific regions of interest without redesigning a new panel.

Each xGen Lockdown Probe is individually synthesised and quality assessed via mass spectroscopy, providing high levels of performance. They are supplied in 96- or 384-well plates, or as pools of up to 2000 oligos. Shipped within 7-10 business days, users can get a quick start on their projects, facilitating the transition from discovery to clinical application.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 4,000+ scientific posters on ePosters
  • More than 5,300+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

TBUSA, IDT Announce Collaboration
Collaboration aims to support targeted RNA Sequencing.
Wednesday, April 27, 2016
IDT Acquires AITbiotech
Acquisition increases capacity to deliver high quality, locally manufactured oligos .
Thursday, December 10, 2015
IDT Expands Oligonucleotide Manufacturing in Singapore
Acquisition increases capacity to deliver high quality, locally manufactured oligos.
Wednesday, December 02, 2015
Dr Patricia Tavormina Named Winner of First IDT ISO 14001 Sustainability Award
Biodiversity research on methane sinks and global warming earns $14,001 in oligo credit.
Thursday, September 10, 2015
Untangling the Web of Gene Expression
New technology for understanding gene expression drives research forward.
Wednesday, May 20, 2015
Discover Affordable Custom NGS Panels
IDT webinar helps NGS researchers bring cost-savings to target capture panels.
Thursday, February 12, 2015
Synthetic Biology Webinar - Genome Modifications Made Easy
IDT reveals how to overcome the challenges of CRISPR-mediated genome editing.
Thursday, January 15, 2015
Discover the Latest NGS-Based Assays Guiding Precision Oncology
IDT joins forces with Foundation Medicine in AMP workshop.
Saturday, November 08, 2014
IDT Acquires SURVEYOR® Nuclease Business from Transgenomic
Addition of SURVEYOR enzyme and kits expands IDT's molecular biology product offerings.
Wednesday, July 02, 2014
World Cup 2014 - with a Scientific Twist
IDT fuses fruit flies, football and fun in a unique global contest with great prizes.
Thursday, June 12, 2014
Summit Partners Makes Growth Equity Investment in IDT
IDT’s founder, Dr. Joseph Walder, will remain the company’s majority owner.
Wednesday, March 19, 2014
Enhanced Molecular Inversion Probes for NGS Target Enrichment
IDT presents latest developments at 15th annual Advances in Genome Biology and Technology meeting.
Tuesday, February 04, 2014
Providing a Rapid and Reliable Method of Gene Cloning
Integrated DNA Technologies will be speaking at the upcoming Antibody Engineering and Therapeutics conference.
Monday, December 02, 2013
IDT Provides Insights into the World of Gene Construction
Informative and educational talk to take place at SynBioBeta 2013.
Thursday, November 14, 2013
Discussing the Science of Big DNA
Read about the most recent advances in synthetic biology in the latest issue of DECODED.
Monday, September 23, 2013
Scientific News
Big Genetics in BC: The American Society for Human Genetics 2016 Meeting
Themes at this year's meeting ranged from the verification, validation, and sharing of data, to the translation of laboratory findings into actionable clinical results.
Personality Traits, Psychiatric Disorders Linked to Specific Genomic Locations
Researchers have unearthed genetic correlations between personality traits and psychiatric disorders.
Genetics Control Regenerative Properties Of Stem Cells
Researchers define how genetic factors control regenerative properties of blood-forming stem cells.
Diabetes Missing Link Discovered
Researchers from the University of Auckland have shown that beta catenin plays a vital role in the control of insulin release from the pancreas.
Study Reveals New Role for Hippo Pathway in Suppressing Cancer Immunity
Hippo pathway signaling regulates organ size by moderating cell growth, apoptosis and stem cell renewal, but dysregulation contributes to cancer development.
Gene-Editing Improves Vision in Blind Rats
Scientists developed a targeted gene-replacement technique that can modify genes in both dividing and non-dividing cells in living animals.
Gene Editing Yields Tomatoes That Ripen Weeks Earlier
Research team develop method to make tomato plants flower and ripen fruit two weeks faster than current growth rates.
Exploring the Genome of the River Blindness Parasite
Researchers have decoded the genome of the parasite that causes the skin and eye infection known as river blindness.
Gene Therapy Maintains Clotting Factor for Hemophilia Patients
Following a single gene therapy dose, the highest levels of an essential blood clotting factor IX were observed in hemophilia B patients.
Unexpected Role for Epigenetic Enzymes in Cancer
Researchers use epigenetics to identify the role of an enzyme family as regulators of genetic message interpretation in yeast.
Skyscraper Banner

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
4,000+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
5,300+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!