Corporate Banner
Satellite Banner
Genomics
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Cancer Biomarkers Identified Using Chromatrap® ChIP Assay

Published: Wednesday, September 12, 2012
Last Updated: Wednesday, September 12, 2012
Bookmark and Share
New approach to ChIP assays - Developed by Porvair Filtration Group.

As the incidence of cancer is expected to affect around 26 million by 2030, clinicians and scientists strive to understand its initiation and proliferation at a molecular level.

Epigenetic research is key to these studies, examining heritable changes in gene expression that occur without the alteration in DNA sequence, and cancer.

Chromatin immunoprecipitation (ChIP) assays are an essential tool in epigenetic research. A new approach to ChIP assays called Chromatrap® has been developed by Porvair Filtration Group.

Based on Porvair’s proprietary BioVyon™ porous plastic materials and taking advantage of its long experience in separation techniques, Chromatrap® ChIP assay kits have particular relevance to identifying cancer biomarkers.

The development of Chromatrap®, a highly sensitive and specific ChIP Assay Kit, is the result of extensive research into chemically functionalizing the internal surfaces of micro porous High Density Polyethylene (HDPE).

Success has meant it is now being adopted in a growing number of new biochemical applications like Chromatrap®.

This novel Chromatrap® technology has been packaged in kits with easy to use spin columns for single use experiments or 96-well high throughput plates, ideal for multiple assays associated with drug screening.

The benefits are far reaching: improved purity with low signal to noise ratios and increased DNA recovery from small cell numbers.

Chromatrap® 96-well high throughput plates will be showcased at Genomics Research Europe, Frankfurt, Germany, 4th-5th September 2012.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,200+ scientific posters on ePosters
  • More than 4,600+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.


Scientific News
Benchtop Automation Trends
Gain a better understanding of current interest in and future deployment of benchtop automated systems.
Higher Frequency of Huntington's Disease Mutations Discovered
University of Aberdeen study shows that the gene change that causes Huntington's disease is much more common than previously thought.
Revealing the Genetic Causes of Bowel Cancer
A landmark study has given the most detailed picture yet of the genetics of bowel cancer — the UK's fourth most common cancer.
The Epigenetic Influences of Chronic Pain
Researchers at Drexel University College of Medicine are aiming to identify new molecular mechanisms involved in pain.
Fighting Resistant Blood Cancer Cells
Biologists present new findings on chronic myeloid leukemia and possible therapeutic approaches.
Tumor Cells Develop Predictable Characteristics
Scientists have discovered that cancer cells at the edge of a tumor that are close to the surrounding environment are predictably different from the cells within the interior of the tumor.
Mothers Obesity Could be Passed on in mtDNA
Obesity can predispose offspring in multiple generations to metabolic problems.
New Imaging Method Reveals Nanoscale Details about DNA
Enhancement to super-resolution microscopy shows orientation of individual molecules, providing a new window into DNA’s structure and dynamics.
Genetic Research Can Significantly Improve Drug Development
With drug development costs topping $1.2bn (£850 million) to get a single treatment to the point it can be sold and used in the clinic, could genetic analysis save hundreds of millions of dollars?
Naked Mole Rat Exhibits “Extraordinary” Cancer Resistance
Scientists are getting closer to understanding the anti-cancer mechanism of the naked mole rat by making induced pluripotent stem cells.
Skyscraper Banner

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,200+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,600+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!