Corporate Banner
Satellite Banner
Scientific Community
Become a Member | Sign in
Home>News>This Article

Cancer Biomarkers Identified Using Chromatrap® ChIP Assay

Published: Wednesday, September 12, 2012
Last Updated: Wednesday, September 12, 2012
Bookmark and Share
New approach to ChIP assays - Developed by Porvair Filtration Group.

As the incidence of cancer is expected to affect around 26 million by 2030, clinicians and scientists strive to understand its initiation and proliferation at a molecular level.

Epigenetic research is key to these studies, examining heritable changes in gene expression that occur without the alteration in DNA sequence, and cancer.

Chromatin immunoprecipitation (ChIP) assays are an essential tool in epigenetic research. A new approach to ChIP assays called Chromatrap® has been developed by Porvair Filtration Group.

Based on Porvair’s proprietary BioVyon™ porous plastic materials and taking advantage of its long experience in separation techniques, Chromatrap® ChIP assay kits have particular relevance to identifying cancer biomarkers.

The development of Chromatrap®, a highly sensitive and specific ChIP Assay Kit, is the result of extensive research into chemically functionalizing the internal surfaces of micro porous High Density Polyethylene (HDPE).

Success has meant it is now being adopted in a growing number of new biochemical applications like Chromatrap®.

This novel Chromatrap® technology has been packaged in kits with easy to use spin columns for single use experiments or 96-well high throughput plates, ideal for multiple assays associated with drug screening.

The benefits are far reaching: improved purity with low signal to noise ratios and increased DNA recovery from small cell numbers.

Chromatrap® 96-well high throughput plates will be showcased at Genomics Research Europe, Frankfurt, Germany, 4th-5th September 2012.

Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,500+ scientific posters on ePosters
  • More than 5,100+ scientific videos on LabTube
  • 35 community eNewsletters

Sign In

Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Scientific News
Integrated Omics Analysis
Studying multi-omics promises to give a more holistic picture of the organism and its place in its ecosystem, however despite the complexities involved those within the field are optimistic.
Unravelling the Role of Key Genes and DNA Methylation in Blood Cell Malignancies
Researchers from the University of Nebraska Medical Center have demonstrated the role of Dnmt3a in safeguarding normal haematopoiesis.
Agilent Presents Early Career Professor Award to Dr. Roeland Verhaak
JAX professor recognized for the development and implementation of workflows for the analysis of big-data from transcriptomics to next generation sequencing approaches.
Ovarian Cancer Insight
Study showed tumours release cytokines to attract macrophages, which secrete growth factors that in turn promote tumour growth.
Bacterial Genes Boost Current in Human Cells
Borrowing and tweaking bacterial genes to enhance electrical activity might treat heart, nervous system injury.
Less Frequent Cervical Cancer Screening
HPV-vaccinated women may only need one screening every 5 to 10 years with screening starting later in life.
Questioning the Safety of Selenium to Combat Cancer
Research indicates the need for change in practice as selenium supplements cannot be recommended for preventing colorectal cancer.
Supercomputers Could Improve Cancer Diagnostics
Researchers push the boundaries of cancer research through high-performance computing to map the human immunone.
Transgenomic, Precipio Diagnostics Merger
Merger will creates a robust diagnostic platform focused on improving accuracy of cancer diagnoses.
Leukaemia Cell Movement Gives Clues to Tackling Treatment-Resistant Disease
Researchers at Imperial College London have suggested that the act of moving itself may help the cells to survive, possibly through short-lived interactions with an array of our own cells.
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,500+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
5,100+ scientific videos