Corporate Banner
Satellite Banner
Genomics
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Cisbio Bioassays Launches Epigenetics Toolbox

Published: Thursday, September 27, 2012
Last Updated: Thursday, September 27, 2012
Bookmark and Share
Pioneer of HTRF® technology expands platform to address growing field of epigenetics therapeutic research.

Cisbio Bioassays has announced the launch of its epigenetics toolbox for use in drug discovery research.

Epigenetics is a crucial field of study for the pharmaceutical and biotechnology industries due to its large range of applications related to human health.

This epigenetics toolbox, which offers a robust and reliable resource for such studies and is based on HTRF® technology, was introduced in Europe at MipTec 2012 in Basel, Switzerland and will be released on October 1st in the United States at Discovery on Target 2012 in Boston, Massachusetts.

Cisbio Bioassays’ epigenetics toolbox is a selection of conjugates specifically developed by the company for epigenetics studies, in response to requests from pharmaceutical and biotechnology researchers for reagents that would help better understand how these events occur through epigenetic mechanisms and how they relate to multiple therapeutic areas and diseases such as metabolic, CNS and immune system disorders.

The toolbox works in combination with Cisbio Bioassays’ other HTRF-based reagents to provide a single, robust and easy-to-use technology for studying classes such as histone methylation and histone demethylation.

“Protein: protein interactions and modifications have long been front and center in drug discovery research and now epigenetics target classes have become highly sought after by researchers because of their broad span of applications,” said François Degorce, head of marketing and communications at Cisbio Bioassays.

Degorce continued, “Epigenetics has become one of Cisbio Bioassays’ core research programs in response to the high demand from clients for more specific study tools, like HTRF, that can be applied to this field. To meet this need, we will regularly implement new assays that allow for studying relevant enzymes and the way in which they function. In fact, our development of this first set of reagents parallels our global commitment to introducing novel tools to our growing catalogue, much as we have been doing with our kinase screening platform throughout the year.”

As part of the development of its kinase screening platform, Cisbio Bioassays has also launched two HTRF cellular kinase assays, Phospho-MEK1 and Phospho-MEK1/2.

These assays, designed for detecting and studying activated MEK when phosphorylated at Ser218 and 222 directly in whole cells, can be used for the investigation of the MAP kinase pathway and therefore the screening of potential anti-cancer therapeutic compounds.

Cisbio’s kinase screening platform now comprises 11 assays - Phospho-CREB (Ser133), Phospho-mTOR (Ser2448) and Phospho-EGFR were introduced in June 2012 - and additional kits are planned in the upcoming months.

All assays feature the benefits of HTRF technology: streamlined protocols, miniaturization and application to any phase of drug screening.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,900+ scientific posters on ePosters
  • More than 4,200+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Cisbio Bioassays and IGF Launch CNS Drug Discovery Research Program
Cisbio Bioassays, member of IBA Group and global provider of HTRF® (homogenous time resolved fluorescence) technology and services to facilitate drug discovery, has announced the launch of the GluSense research and development program in partnership with the Functional Genomics Institute of Montpellier, France.
Tuesday, November 30, 2010
Scientific News
Light Signals from Living Cells
Fluorescent protein markers delivered under high pressure.
Counting Cancer-busting Oxygen Molecules
Researchers from the Centre for Nanoscale BioPhotonics (CNBP), an Australian Research Centre of Excellence, have shown that nanoparticles used in combination with X-rays, are a viable method for killing cancer cells deep within the living body.
Genomic Signature Shared by Five Types of Cancer
National Institutes of Health researchers have identified a striking signature in tumor DNA that occurs in five different types of cancer.
Genetic Cause of Rare Allergy
Institute has identified a genetic mutation responsible for a rare form of inherited hives induced by vibratory urticaria.
Mitochondria Shown to Trigger Cell Ageing
An international team of scientists has for the first time shown that mitochondria, the batteries of the cells, are essential for ageing.
Cancer Cells Kill Off Healthy Neighbours
Cancer cells create space to grow by killing off surrounding healthy cells, according to UK researchers working with fruit flies.
Validating the Accuracy of CRISPR-Cas9
IBS Researchers create multiplex Digenome-seq to find errors in CRISPR-Cas9 processes.
Cancer Drug Target Visualized at Atomic Resolution
New study using cryo-electron microscopy shows how potential drugs could inhibit cancer.
Genetic Mechanism Behind Cancer-Causing Mutations
Researchers at Indiana University has identified a genetic mechanism that is likely to drive mutations that can lead to cancer.
"Gene Fusion" Drives Childhood Brain Cancers
Study co-led by Penn scientists highlights potential targets for future cancer therapies.
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,900+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,200+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!