Satellite Banner
Genomics
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Life Technologies Launches Industry's First Stem Cell Characterization Panel

Published: Monday, June 17, 2013
Last Updated: Monday, June 17, 2013
Bookmark and Share
Developed with Harvard University, TaqMan® hPSC Scorecard™ Panel provides a benchmark against which researchers can evaluate pluripotency and potential of cell lines.

Life Technologies Corporation has launched the TaqMan® hPSC Scorecard™ Panel, a first-of-its-kind characterization assay that establishes a standardized benchmark against which researchers can now evaluate pluripotency and trilineage differentiation potential in human embryonic (ES) and induced pluripotent stem (iPS) cell lines.

Life will showcase the technology during the International Society for Stem Cell Research (ISSCR) conference in Boston June 12-15.

Until now, scientists have evaluated pluripotency - the potential for ES and iPS cells to differentiate into any cell type - with laborious, costly and non-standardized methods that provide ambiguous results.

Additionally, their inability to accurately determine cell lines' propensity to differentiate into one of the three primary cell germ layers has contributed to major hurdles that impede stem cell technology from moving into the clinic.

The TaqMan® hPSC Scorecard™ Panel, however, relies on a specific range of gene expression levels identified at Harvard University to accurately characterize cell lines in two critical areas: pluripotency and lineage bias.

The panel is also being offered with cloud-based software for rapid data analysis and data sharing among research collaborators.

"The rapid advancements in stem cell research over the last few years have created a need for more effective and standardized methods for characterizing pluripotent cells," said Alex Meissner, Ph.D., Associate Professor, Department of Stem Cell and Regenerative Biology, Harvard University.

Meissner continued, "Today, the field of genomics is helping to meet that demand through development of novel approaches that can help deliver the promise of stem cells."

Life Technologies developed the TaqMan® hPSC Scorecard™ Panel in collaboration with Dr. Meissner. He is the lead author of a study in the journal Cell (Vol. 144, No. 3, pp. 439-452, Feb. 4, 2011) who identified a range of expression levels among key genes associated with pluripotency.

By measuring gene activity in ES and iPS cells against the study's gene expression range, Dr. Meissner's lab was able to accurately score cells for their potential to differentiate into particular cell lineages.

Standardizing characterization allows researchers to work more efficiently by enabling them to quickly identify the most promising cells.

It also helps accelerate various applications, including development of "disease-in-a-dish" models from patient-derived cells, drug screening and eventual use of pluripotent cells as a renewable source for transplantation medicine.

"It has become increasingly critical for researchers to consistently and accurately characterize the cells they are working with, particularly to realize the promise of stem cell-based technology in drug discovery and clinical applications," said Chris Armstrong, Ph.D., General Manager and Vice President of Primary and Stem Cell Systems at Life Technologies.

Armstrong continued, "As such, the launch of this novel characterization panel supports our continued commitment to provide our customers with the most innovative products across the pluripotent stem cell workflow."

Dr. Meissner will give a presentation on his lab's use of the TaqMan® hPSC Scorecard™ Panel during one of two Innovation Showcases Life Technologies will host at ISSCR in Room 257 A-B on June 14. His talk takes place from 12:30-1 p.m.

The second Innovation Showcase will feature Dr. Birgitt Schuele, M.D., Assistant Professor, Clinical Molecular Geneticist, The Parkinson's Institute, who will present her lab's use of Sendai virus-based CytoTune® reprogramming technologies to recapitulate phenotypes associated with Parkinson's Disease.

Her presentation will take place from 11:45 a.m.-12:15 p.m. For more information on the Innovation Showcases, visit the Life Technologies ISSCR booth (# 630).

TaqMan® hPSC Scorecard™ Panel is For Research Use Only, not intended for diagnostic purposes.


Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,400+ scientific posters on ePosters
  • More than 3,700+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

KACST Partners with Life Tech in The Saudi Human Genome Program
Program aims to analyze 100,000 human genomes to identify the causes of disease in the population of the Kingdom of Saudi Arabia and the Arab world.
Monday, December 09, 2013
Life Technologies Awards Digital PCR Innovation Grants to Five Research Labs
The five Innovation Grant recipients in the Digital PCR Applications Grant Program was announced during the ASHG conference in Boston.
Thursday, October 24, 2013
Thermo Acquisition Approved by Life Technologies Stockholders
Company announced that its stockholders voted to adopt the previously announced merger agreement.
Thursday, August 22, 2013
Life Technologies Enters into an Exclusive License and Supply Agreement for Dynabead
Life Technologies has signed a long-term supply and exclusive licensing agreement with Novartis for immunotherapeutics involving T cells modified to express chimeric antigen receptors for the treatment of cancer.
Thursday, August 01, 2013
Life Technologies Announces Second Quarter 2013 Results
Revenue increased 1% excluding impact of currency.
Thursday, August 01, 2013
Life Technologies Signs Five-Year Agreement with the FDA
The agreement aims to accelerate and advance food safety testing of E. coli and Salmonella, two foodborne contaminants commonly associated with outbreaks and/or recalls.
Tuesday, July 30, 2013
Roswell Park Cancer Institute Purchases Six Ion Torrent Sequencers
Life Technologies Corporation announced that the new Center for Personalized Medicine at Roswell Park Cancer Institute has purchased four Ion Proton™ sequencers and two Ion Personal Genome Machine™ sequencers.
Thursday, February 21, 2013
Boston Children's Hospital and Life Technologies Launch Claritas Genomics, a Clinical Genomics Company
Spinoff venture will develop genomic sequencing solutions utilizing Ion Torrent technology for clinical applications.
Thursday, January 10, 2013
Life Technologies introduces Ion AmpliSeq™ Community Panels
Ion AmpliSeq™ Community Panels leverages the expertise of scientific thought leaders and the Ion Community to create gene panels for conditions ranging from cancer to inherited diseases.
Wednesday, November 07, 2012
Life Technologies Acquires Compendia Bioscience
Acquisition expands Life Technologies' ability to drive progress in personalized medicine
Sunday, October 14, 2012
Life Technologies Acquires Compendia Bioscience
Bioinformatics expertise will enable deeper engagement with established customer base of leading pharmaceutical companies.
Tuesday, October 09, 2012
Life Technologies Signs Collaborative Agreement with Structural Genomics Consortium
Pioneering joint venture releases 58 of 200 planned, highly-specific recombinant antibodies for epigenetic studies.
Thursday, July 19, 2012
Life Technologies Collaborate with University of North Texas Health Science Center
University of North Texas Health Science Center advances forensic research by investing in semiconductor DNA sequencing technology.
Thursday, June 21, 2012
SickKids Adopts Life Technologies' Ion Proton™ Sequencer to Launch New Centre for Genetic Medicine
Long-term partnership will focus on sequencing 10,000 genomes per year to revolutionize pediatric disease research in Canada.
Thursday, June 21, 2012
Life Technologies Teams with Universitry of North Texas
University Advances Forensic Research by Investing in Semiconductor DNA Sequencing Technology.
Thursday, June 21, 2012
Scientific News
RNAi Screening Trends
Understand current trends and learn which application areas are expected to gain in popularity over the next few years.
Tracking Breast Cancer Before it Grows
A team of scientists led by University of Saskatchewan researcher Saroj Kumar is using cutting-edge Canadian Light Source techniques to screen and treat breast cancer at its earliest changes.
DNA Damage Seen in Patients Undergoing CT Scanning
Along with the burgeoning use of advanced medical imaging tests over the past decade have come rising public health concerns about possible links between low-dose radiation and cancer.
The Mystery of the Instant Noodle Chromosomes
Researchers from the Lomonosov Moscow State University evaluated the benefits of placing the DNA on the principle of spaghetti.
Oxitec ‘Self-Limiting Gene’ Offers Hope for Controlling Invasive Moth
A new pesticide-free and environmentally-friendly way to control insect pests has moved ahead with the publication of results showing that Oxitec diamondback moths (DBM) with a ‘self-limiting gene’ can dramatically reduce populations of DBM.
Web App Helps Researchers Explore Cancer Genetics
Brown University computer scientists have developed a new interactive tool to help researchers and clinicians explore the genetic underpinnings of cancer.
Kiwi Bird Genome Sequenced
The kiwi, national symbol of New Zealand, gives insights into the evolution of nocturnal animals.
Scientists Identify Schizophrenia’s “Rosetta Stone” Gene
Scientists have identified a critical function of what they believe to be schizophrenia’s “Rosetta Stone” gene that could hold the key to decoding the function of all genes involved in the disease.
Yeast Cells Use Signaling Pathway to Modify Their Genomes
Researchers at the Babraham Institute and Cambridge Systems Biology Centre, University of Cambridge have shown that yeast can modify their genomes to take advantage of an excess of calories in the environment and attain optimal growth.
Nanoparticles Can Clean Up Environmental Pollutants
Researchers have found that nanomaterials and UV light can “trap” chemicals for easy removal from soil and water.
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,400+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
3,700+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FREE!