Corporate Banner
Satellite Banner
Scientific Community
Become a Member | Sign in
Home>News>This Article

InSphero to Distribute Dainippon Screen Imager for Rapid Profiling of 3D Microtissues

Published: Tuesday, April 08, 2014
Last Updated: Tuesday, April 08, 2014
Bookmark and Share
The Cell'iMager, to be marketed in the US and Europe, simplifies growth and morphological profiling of 3D microtissues.

InSphero AG and Dainippon Screen (Kyoto, Japan) announced today they have reached a
distribution agreement for InSphero to begin marketing Dainippon Screen's Cell'iMager in North
America and Europe. Dainippon Screen selected InSphero based on their in-depth know-how
pertaining to 3D microtissue biology and applications. The CelriMager is fully compatible with
InSphero's GravityTRAPTm 3D microtissue assay platform and other 3D-cell culture plates,
providing rapid, robust profiling of microtissue growth and morphology.

3D tumor microtissues or spheroids are increasingly used in drug discovery and development as
a more representative biological model for testing drug sensitivity and efficacy. Size and
morphology are important determinants to evaluate the biological behavior of 3D microtissues,
particularly in development of anti-cancer drugs, where monitoring cell growth is a particularly
critical endpoint. High-throughput, accurate assessment of 3D microtissue size and growth in
these applications is currently limited by sequential, time-consuming and often manual optical

The innovative CelriMager's high-resolution scanning optics provide rapid direct measurement
of multiple endpoints, including microtissue diameter, area, pseudo-volume, and circularity at a
resolution of up to 9600 dpi. The system can analyze four 96- or 384-well plates in a single run,
in as little as one minute per plate, enabling fast and label-free visualization of even small size
differences. The scanner software is tailored for the analysis of 3D microtissues, allowing
adjustment of parameters such as focal plane, minimum and maximum object size, scan area,
and resolution for developing protocols specific to a given tissue type or assay.
The instrument is already broadly used in Japan and is now available in North America and
Europe through InSphero's experienced sales team.

InSphero CEO and co-founder Dr. Jan Lichtenberg sees the agreement as an exciting next step
toward making InSphero a total solution provider for the 3D cell culture marketplace. "Adding
the Cell3iMager to our portfolio gets us closer to offering our customers a complete set of
solutions for 3D cell based assays — from the assay-ready 3D cell model, to assay reagents and
instruments for endpoint analysis."

Mr. Kunihisa Hashimoto, General Manager of Dainippon Screen's Imaging and Solutions
Division, noted the agreement with InSphero is also a major step for Dainippon Screen.
"Combining InSphero's GravityTRAPTm plates and microtissues with the imaging technology of
our Cell'iMager is sure to streamline and simplify research using 3D tissue cultures. We are
excited to leverage InSphero's expertise in the 3D marketplace to help bring our innovative
imaging system to North America and Europe."

Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,800+ scientific posters on ePosters
  • More than 4,000+ scientific videos on LabTube
  • 35 community eNewsletters

Sign In

Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

InSphero Publishes 3D Tumor-Stroma Model for Non-Small Cell Lung Cancer
PLOS One article delivers promising co-culture method to mimic tumor microenvironment, demonstrating potential for biomarker and drug discovery.
Thursday, April 24, 2014
Scientific News
New Class of RNA Tumor Suppressors Identified
Two short, “housekeeping” RNA molecules block cancer growth by binding to an important cancer-associated protein called KRAS. More than a quarter of all human cancers are missing these RNAs.
Biologists Induce Flatworms to Grow Heads and Brains of Other Species
Findings shed light on role of a new kind of epigenetic signaling in evolution, could yield clues for understanding birth defects and regeneration.
Turning up the Tap on Microbes Leads to Better Protein Patenting
Mining millions of proteins could become faster and easier with a new technique that may also transform the enzyme-catalyst industry, according to University of California, Davis, researchers.
Mathematical Model Forecasts the Path of Breast Cancer
Chances of survival depend on which organs breast cancer tumors colonize first.
Exploring the Causes of Cancer
Queen's research to understand the regulation of a cell surface protein involved in cancer.
Ancient Viral Molecules Essential for Human Development
Genetic material from ancient viral infections is critical to human development, according to researchers at the Stanford University School of Medicine.
Tardigrade's Are DNA Master Thieves
Tardigrades, nearly microscopic animals that can survive the harshest of environments, including outer space, hold the record for the animal that has the most foreign DNA.
The Secret Behind the Power of Bacterial Sex
Migration between different communities of bacteria is the key to the type of gene transfer that can lead to the spread of traits such as antibiotic resistance, according to researchers at Oxford University.
Farming’s in Their DNA
Ancient genomes reveal natural selection in action.
GMO Food Animals Should be Judged by Product, Not Process
In a world with a burgeoning demand for meat, milk and eggs, regulatory policies around the use of biotechnologies in agriculture need to be based on the safety and attributes of those foods rather than on the methods used to produce them, says a UC Davis animal scientist.
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,800+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,000+ scientific videos