Corporate Banner
Satellite Banner
Biomolecular Screening
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

AnaSpec Introduces Pancreatic ß-Cells Specific Antibodies

Published: Monday, September 24, 2012
Last Updated: Monday, September 24, 2012
Bookmark and Share
Company releases three antibodies against FXYD2?a.

AnaSpec has announced the release of three antibodies (two monoclonal and one polyclonal) against FXYD2γa.

FXYD2γa is a regulating subunit of the NA+-K+-ATPase and has been identified as a unique and specific pancreatic beta cell surface biomarker.

In individuals with Type 1 diabetes or in pancreatic sections of streptozotocin-treated Macacus cynomolgus monkeys, loss of FXYD2γa has been closely correlated with a loss of insulin positive cells.

Anti-hFXYD2γa antibodies are purified antibodies reacting with an 11 amino acid residue peptide of FXYD2γa.

Monoclonal anti-FXYD2γa antibodies from Clone 4F9G9 show high specificity towards FXYD2γa beta-cell biomarker while monoclonal anti-FXYD2γa antibodies from Clone 3C1D10 show high sensitivity towards FXYD2γa beta-cell biomarker.

A rabbit polyclonal anti-hFXYD2γa antibody is also available (see Table 1). These antibodies can be used for beta cell specific targeting and non-invasive imaging.

The use of targeting strategies against the biomarker (FXYD2γa) allows early identification of beta cell and the follow up of therapies for diabetes patients.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,900+ scientific posters on ePosters
  • More than 4,200+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.


Scientific News
New Biomarker to Assess Stem Cells Developed
A research team led by scientists from UCL have found a way to assess the viability of 'manufactured' stem cells known as induced pluripotent stem cells (iPSCs). The team's discovery offers a new way to fast-track screening methods used in stem cell research.
A Better Model for Parkinson's
Scientists at EPFL solve a longstanding problem with modeling Parkinson’s disease in animals. Using newfound insights, they improve both cell and animal models for the disease, which can propel research and drug development.
Faster Drug Discovery?
Startup develops more cost-effective test for assessing how cells respond to chemicals.
Microalgae Make a Splash in the UK Cosmeceutical Market
Scottish innovators have discovered an anti-viral and anti-inflammatory carbohydrate in microscopic algae (microalgae) which has huge potential to change the cosmetics market.
Mechanism of Tumor Suppressing Gene Uncovered
The most commonly mutated gene in cancer,p53, works to prevent tumor formation by keeping mobile elements in check that otherwise lead to genomic instability, UT Southwestern Medical Center researchers have found.
Experimental Combination Surprises with Anti-HIV Effectiveness
A compound developed to protect the nervous system from HIV surprised researchers by augmenting the effectiveness of an investigational antiretroviral drug beyond anything expected.
Useful Colon Cancer Biomarker Discovered
Biomarker is detectable with simple, inexpensive test.
A New Type of Anticancer Agent
Success in the development of a ?-tubulin specific inhibitor.
Seeing Hope
Gene therapy/drug combo restores some vision in mice with optic nerve injury.
Versatile New Molecule-Building Technique
Chemists at The Scripps Research Institute (TSRI) have devised a new and widely applicable technique for building potential drug molecules and other organic compounds.
SELECTBIO

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,900+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,200+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!