Corporate Banner
Satellite Banner
Biomolecular Screening
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

NIH Awards New England Biolabs Grant for the Research and Development of Novel Enzymes for Epigenetic Studies

Published: Friday, November 09, 2012
Last Updated: Friday, November 09, 2012
Bookmark and Share
New England Biolabs (NEB) has recently received a $640,000 Phase II Small Business Innovation Research (SBIR) grant to expand its research and product development of novel enzymatic tools for epigenetic analysis.

This latest grant adds to the more than $1.1 million of SBIR funds awarded for this research since 2009.

Since its establishment in 1974, NEB has been dedicated to the discovery and development of reagents for the life sciences industry. A key to this effort has been the focused development of recombinant enzyme technology by NEB scientists, resulting in  a wide array of enhanced tools for molecular biology research and analysis, such as engineered restriction enzymes with greater specificity under a wider range of reaction conditions. This commitment has placed NEB at the forefront of restriction enzyme research and supply.

The use of restriction enzymes in epigenetic studies has been a research focus at NEB for many years. Specifically, research in the area of methylation-dependent and methylation-sensitive restriction enzymes has led to the discovery and commercialization of new tools to identify these DNA modifications. For example, in 2010, NEB scientists identified the MspJI family of restriction enzymes, which has the ability to excise small fragments of methylated DNA for use in epigenetics studies. This latest SBIR grant award enables further research in this area, and ultimately a deeper understanding of epigenetic marks in the mammalian genome.

"Since its founding, NEB has coupled its basic research with the development of new tools for molecular biology," states Dr. Bill Jack, Director of Research at NEB. "The repository of knowledge, generated during the almost four decades of restriction endonuclease study at NEB, has fueled a discovery program that has radically expanded the utility of restriction endonucleases and activity on a variety of DNA templates, including those created by epigenetic modification. We are committed to continuing this discovery process, and to use these novel new enzyme.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,300+ scientific posters on ePosters
  • More than 4,900+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.


Scientific News
Automated Patch Clamping Trends
Learn more about current practices, preferences and metrics in ion channel drug screening using APC technology.
Mechanisms of Calcium Blockers
Researchers describe how the fundamental mode of action of two distinct chemical classes of calcium channel blockers differs.
Breakthrough in GPCR Understanding
Integral Molecular announces breakthrough in understanding the functionality of GPCRs, the largest class of drug targets in human disease.
Enzyme that Triggers Cell Demise in ALS Identified
Scientists from Harvard have identified a key instigator of nerve cell damage in people with amyotrophic lateral sclerosis (ALS).
Fly Study into Therapies for HVP-Induced Cancer
Fruit flies may help scientists understand the mechanism by which HPV can cause cancer as well as identify potential drug treatments.
World's Most In-Depth Study to Detect Alzheimer's Disease
A multisite team will see the most thorough and vigorous testing for Alzheimer's ever performed on volunteers.
'Missing Evolutionary Link' of Natural Drug Source Found
Scripps Florida study finds 'missing evolutionary link' of a widely used natural drug source
Grad Student's Finding Enables Rapid Compound Screening
Grad student makes technical leap that could enable rapid screening of anti-cancer compounds.
Uncovering Constructor Proteins
Scientists have discovered a new bacterial cell wall builder that could be a target for antibiotic development.
Cholesterol Linked to Aggressive Cancers
Research suggests fats, such as cholesterol, can increase aggressive cancer progression.
SELECTBIO

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,300+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,900+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!