Corporate Banner
Satellite Banner
Biomolecular Screening
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Cerilliant Offers New Certified Spiking Solutions®

Published: Thursday, November 29, 2012
Last Updated: Thursday, November 29, 2012
Bookmark and Share
Preparation of calibrators and controls in nicotine testing and other clinical or diagnostic applications by LC/MS or GC/MS.

Cerilliant has introduced new Certified Spiking Solutions® of nicotine metabolites norcotinine and trans-3-hydroxycotinine as well as nicotine nitrosamines NNN, NNK, and NAB at concentrations of 1.0 mg/mL in methanol for each solution standard.

These certified reference solutions can be used as Snap-N-Spike® starting materials in the laboratory’s matrix of choice for preparation of calibrators and controls in nicotine testing and other clinical or diagnostic applications by LC/MS or GC/MS.

Nicotine biomarkers are commonly monitored in patients who smoke cigarettes, use other nicotine products such as nicotine gum and electronic cigarettes, or are exposed to environmental tobacco smoke.

Accurate patient results in clinical and diagnostic testing of nicotine use depend on accurate and consistent Certified Reference Materials for the numerous nicotine metabolites.

Neat material handling of nicotine analogs and their preparation as certified reference solutions offer significant challenges to the laboratory due to high toxicity of the neat materials and their sensitivity to air and light.

Cerilliant’s validated process includes manufacturing controls for sensitive compounds such as raw material handling and solution preparation under inert conditions and flame-sealing of ampoules under argon to minimize degradation and promote long-term shelf life.

Toxic materials are handled in isolation chambers and are gravimetrically prepared using precision balances which have been qualified to ensure minimal uncertainty.

“Protection of both production staff and the correct handling of these highly toxic neat materials are of paramount importance in the preparation of these solution standards. Consequently the formulation of the nicotine metabolites is limited to staff who have received and passed the appropriated level of internal training through our proficiency testing program to ensure proper use of equipment and accurate preparation using the glove boxes,” added Gregory Kirkovits, PhD, manager of the Standards & Packaging group.

Cerilliant’s latest nicotine metabolite and nitrosamine products complement their current offering of Certified Spiking Solutions® for nicotine, including anabasine, cotinine, and nornicotine and their internal standards, all offered at concentrations suitable for dilution to working levels in the laboratory’s matrix of choice.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,000+ scientific posters on ePosters
  • More than 4,500+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.


Scientific News
It’s Now Easier To Go With The Flow
Rice University tool simplifies comparison of flow cytometry data for laboratories.
FNIH Launches Project to Evaluate Biomarkers in Cancer Patients
Company has announced that it has launched a new project to evaluate the effectiveness of liquid biopsies as biomarkers in colorectal cancer patients.
Drugs that May Combat Deadly Antibiotic-Resistant Bacteria Uncovered
Study identifies 79 compounds that inhibit carbapenem-resistant Enterobacteriaceae (CRE).
Making Precision Medicine a Reality
Researchers are one step closer to understanding the genetic and biological basis of diseases like cancer, diabetes, Alzheimer’s and rheumatoid arthritis – and identifying new drug targets and therapies.
Potential “Good Fat” Biomarker
New method to measure the activity of energy consuming brown fat cells could ease the testing weight loss drugs.
MicroRNA Pathway Could Lead to New Avenues for Leukemia Treatment
Cancer researchers at the University of Cincinnati have found a particular signaling route in microRNA (miR-22) that could lead to targets for acute myeloid leukemia, the most common type of fast-growing cancer of the blood and bone marrow.
Soy Shows Promise as Natural Anti-Microbial Agent
Soy isoflavones and peptides may inhibit the growth of microbial pathogens that cause food-borne illnesses, according to a new study from University of Guelph researchers.
Doubling Down on Dengue
HMS researchers have discovered two ways a compound blocks dengue virus.
Soy Shows Promise as Natural Anti-Microbial Agent
Researchers from University of Guelph show that soy isoflavones and peptides could be used to reduce microbial contamination of food.
AstraZeneca to Sequence 2 Million Genomes in Search for New Drugs
Company launches integrated genomics approach which aims to transform drug discovery and development.
SELECTBIO

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,000+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,500+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!