Corporate Banner
Satellite Banner
Biomolecular Screening
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Leading Tuberculosis Experts Explore Shortcomings in Current Immigrant TB Screening Policy

Published: Tuesday, December 04, 2012
Last Updated: Tuesday, December 04, 2012
Bookmark and Share
Improved immigration policy and replacement of century-old diagnostic tests have potential to significantly reduce cases of latent tuberculosis in the UK.

Leading scientists and experts in the field of tuberculosis (TB) are meeting today to discuss how to improve national prevention strategies for the control of TB. UK is one of few countries in Western Europe which has seen an increase in the number of active TB cases in recent years. The group, chaired by Professor Peter Davies, Consultant Chest Physician at Liverpool Heart and Chest Hospital and Dr Onn Min Kon, Consultant Respiratory Physician at St Mary’s Hospital, is expected to acknowledge recent findings that current UK immigrant screening procedures miss more than 70 per cent of latent TB infection and develop a consensus on how replacing current diagnostic tools with new cutting-edge technology, can reduce disease burden and cost.

TB remains one of the most contagious and prevalent diseases in the world, with approximately nine million active cases globally. It is estimated that there are also about two billion people around the world infected with latent, or inactive, TB. Research shows that in people with latent TB, preventative treatment can reduce the risk of developing active TB by as much as 90 per cent – demonstrating the importance of identifying and treating latent disease.

In Britain, cases of TB increased by almost 50 per cent between 1989 and 2009, with 9,040 cases reported in the UK in 2009; in 2011, TB reached its highest peak in 30 years. Foreign-born individuals account for nearly three quarters of the country’s TB cases.

“A significant proportion of active TB cases in the UK stem from immigrants carrying latent TB, whose infections are ‘reactivated’ at some point after they arrive in this country” said meeting co-chair Professor Peter Davies, Consultant Chest Physician at Liverpool Heart and Chest Hospital. “Compounding this is that the diagnostic test that has traditionally been used for identifying latent TB infection is more than 100 years old, and is often inaccurate. Clearly, this is a two-pronged problem that requires a two-pronged solution – we need clearer strategies for testing for latent disease among immigrants, and better diagnostic tests to enable us to do so.”

The tuberculin skin test (TST), the tool traditionally used to identify latent TB infection, is the oldest diagnostic test in medical practice, and is widely acknowledged to have shortcomings in relation to specificity and is more difficult to administer in practice. To combat the lack of an acceptable test for latent TB, new, highly-specific and faster tests have been developed, known as interferon-gamma release assays (IGRAs). Already widely used in US, Europe and Asia, IGRAs have demonstrated significant value in both accurate diagnosis of the disease and cost-effectiveness of the tests, and data show that this cost-effectiveness would be replicated should IGRAs be used in the UK.

“We urgently need to stem the tide of rising TB cases in the UK,” said meeting co-chair Dr Onn Min Kon, Consultant Respiratory Physician at St Mary’s Hospital. “This is not a problem that can be tackled by healthcare professionals alone – it needs to be a joint effort with policy and society. We look forward to an informative discussion about how best to tackle the influx of TB infection stemming from the immigrant community, and how to incorporate the new, and much more efficient and effective, IGRA testing into our efforts to screen for and prevent the spread of TB.”

QIAGEN is sponsoring this symposium as part of their ongoing commitment to the field of TB.

QIAGEN markets the QuantiFERON-TB Gold, the leading test for detection of latent TB, which has worldwide approvals and is recommended in several national and international guidelines.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,900+ scientific posters on ePosters
  • More than 5,300+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

QIAGEN Partners to Develop Predictive Tests in Oncology
Collaboration with Therawis addresses unmet need to guide clinical decisions in breast cancer.
Friday, May 27, 2016
QIAGEN,Biotype Diagnostics Form Partnership
New “Biotype Innovation” to develop workflows for personalized health-care and other applications based on QIAGEN’s ModaPlex platform.
Monday, June 29, 2015
Hitachi High-Technologies, QIAGEN Collaborate
Hitachi High-Technologies Corporation and QIAGEN N.V. have entered into a long-term strategic collaboration involving initiatives to deliver important advances in molecular testing.
Thursday, June 18, 2015
QIAGEN Signs Ninth Master Collaboration Agreement for Companion Diagnostics
Master collaboration agreement is a framework for developing and commercializing QIAGEN companion diagnostics, paired with new or existing products.
Thursday, November 13, 2014
QIAGEN Licenses Blood Cancer Biomarkers
Exclusive global license from University of Tokyo enables development of QIAGEN assays for SF3B1 mutations, including NGS gene panels, for blood cancers.
Saturday, July 26, 2014
QIAGEN, Lilly form CDx Collaboration
Companies to co-develop companion diagnostics for simultaneous analysis of DNA and RNA biomarkers in common cancers.
Friday, May 30, 2014
FDA Approve QIAGEN PCR Kit For Use With Second Colorectal Cancer Drug
Clinically proven companion diagnostic gains U.S. approval to guide use of Amgen’s Vectibix® (panitumumab) in treatment of metastatic colorectal cancer.
Tuesday, May 27, 2014
QIAGEN Licences Biomarker for Blood Disorder from CeMM Vienna
Company plans to develop a molecular diagnostic test for the calreticulin mutations.
Thursday, April 10, 2014
QIAGEN Partners with Exosome Diagnostics
Molecular testing of biofluids promises unprecedented access to gene mutations, gene expression signatures and expression levels without costly, invasive tissue biopsies.
Wednesday, July 24, 2013
QIAGEN Expands Pipeline of Promising New Biomarkers for Development of Companion Diagnostics
Several lymphoma-related biomarkers, including EZH2 Y641 gene mutations, rights acquired from British Columbia Cancer Agency.
Monday, June 10, 2013
QIAGEN and Cardinal Health Collaborate to Offer Molecular Diagnostic Products to Smaller and Mid-Sized U.S. Hospitals
Collaboration creates distribution channel to previously underserved market segment.
Tuesday, May 01, 2012
QIAGEN to Supply Molecular Screening Solutions to Increase Safety of Blood Donations in Brazil
The supply agreement covers molecular sample and assay technologies for a national PCR-based blood screening program for HIV and HCV.
Friday, June 05, 2009
QIAGEN to Supply Molecular Screening Solutions to Increase Safety of Blood Donations in Brazil
The agreement to supply molecular sample and assay technologies for a PCR-based blood screening program for HIV HCV in Brazil.
Friday, May 29, 2009
QIAGEN Tests Clinically Verified for the Monitoring of Swine Flu
German Bernhard Nocht Institute and Spanish Reference Laboratory detect infections with the H1N1 strain using QIAGEN’s artus influenza test.
Monday, May 04, 2009
QIAGEN and CNCI to Establish Cervical Cancer Screening Program in Kolkata
The initiative will be conducted over 5 years and is expected to reach 50,000 women.
Monday, April 27, 2009
Scientific News
Stem Cells in Drug Discovery
Potential Source of Unlimited Human Test Cells, but Roadblocks Remain.
Survey of New York City Soil Uncovers Medicine-Making Microbes
Microbes have long been an invaluable source of new drugs. And to find more, we may have to look no further than the ground beneath our feet.
'Lab on the Skin' for Sweat Analysis
Northwestern University researchers develop a low-cost wearable electronic device that collects and analyzes sweat for health monitoring.
Toxoplasma’s Balancing Act Explained
Parasite’s method of rewiring our immune response leads to novel tool for drug tests.
Cancer Signaling Pathway Illuminating Way To Therapy
Researchers refine a pro-growth signalling pathway, common to cancers, that can kill cancer cells while leaving healthy cells unharmed.
Breast Cancer Cells Starve for Cystine
Depriving triple negative breast cancer, a treatment-resistant form of breast cancer, of cystine results in cancer cell death.
T Cell Channel Could Be Targeted to Treat Cancers
Researcher identify ion-channel found within T cells that could be targeted to reduce development of neck and head cancers.
Novel Urine Test to Predict High-Risk Cervical Cancer
Preliminary studies affirm accuracy and potential cost savings to screen for virus-caused malignancy.
Biomarker Guiding Cancer Therapy
Biologists link levels of Mena protein to breast cancer cells’ sensitivity to chemotherapy.
Protein Array Can Pinpoint Cancer Biomarker
A novel detection method for the detection of glycoproteins has been developed.
SELECTBIO

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,900+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
5,300+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!