Corporate Banner
Satellite Banner
Biomolecular Screening
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

CYTOO’s 2D+ Technology and Institut Curie’s Organelle Map in the limelight at SLAS 2013

Published: Monday, January 07, 2013
Last Updated: Monday, January 07, 2013
Bookmark and Share
CYTOO will attend the Society for Laboratory Automation and Screening (SLAS) 2013 conference on 12-16 Jan, in Orlando, Florida, USA.

The company will present their 2D+ Solutions, opening fresh perspectives for cell based assay development in drug discovery.

2D+ Solutions are based on CYTOO’s standard and custom adhesive micropatterns in 96-well plates which guide cell architecture and behavior. By defining the 2D topology of cell adhesion, the 2D+ Cell Culture Platform enables fine control of the spreading and 3D shape of cultured cells in single- or multi-cellular configurations. This approach results in control of cell contractility, cell polarity, organelle positioning, and cell division axis.

2D+ Custom Solutions are specifically designed to bring expertise, resources and technology to address current bottlenecks in cell based assay development and screening in drug discovery.

2D+ Custom Solutions include: Exploratory solutions to guide customers through the initial exploration of the 2D+ technology with experienced PhD-level expert support; Assay development to select the best ecosystem for the requested cells; Screening to run pilot or full sized screens. All Solutions are tailored to the customer’s needs and can be carried out in the customer’s facilities or outsourced to CYTOO, on our fully equipped HCS screening platform.

The 2D+ technology addresses a major concern with traditional 2D culture, in which cells spread and move in an uncontrolled manner, introducing a considerable but unnoticed variability in cell function. Kristine Schauer, from the Institut Curie in Paris, France, used the crossbow adhesive micropatterns to get reproducible shape and distribution of intracellular compartments and developed a mathematical algorithm to generate and compare probabilistic density maps of the different endosome compartments.

This innovative approach is a powerful universal method to identify statistically relevant hits and drug effects in complex cell based assays, and according to Michel Bornens, COO at CYTOO “the method has now the potential to become a gold-standard in the quantitative analysis of cell-based high-throughput data”. Kristine Schauer’s Organelle Map figures among the nine 2013 SLAS Innovation Award finalists. A $10,000 cash prize will be attributed during SLAS 2013, and recognizes extraordinary achievement in innovative laboratory science and technology.

Attendees are invited to visit booth #310 to discuss their application with François Chatelain, President and CEO, and Lisa Minor, Application Development Leader.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,900+ scientific posters on ePosters
  • More than 4,200+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.


Scientific News
Charting Kidney Cancer Metabolism
Changes in cell metabolism are increasingly recognized as an important way tumors develop and progress, yet these changes are hard to measure and interpret. A new tool designed by MSK scientists allows users to identify metabolic changes in kidney cancer tumors that may one day be targets for therapy.
Insights into the Function of the Main Class of Drug Targets
About thirty percent of all medical drugs such as beta-blockers or antidepressants interact with certain types of cell surface proteins called G protein coupled receptors.
Visualizing a Cancer Drug Target at Atomic Resolution
Using cryo-electron microscopy, researchers were able to view, in atomic detail, the binding of a potential small molecule drug to a key protein in cancer cells.
Honey’s Potential to Save Lives
The healing powers of honey have been known for thousands of years.
3-D Printed Lifelike Liver Tissue for Drug Screening
A team led by engineers at the University of California, San Diego has 3D-printed a tissue that closely mimics the human liver's sophisticated structure and function. The new model could be used for patient-specific drug screening and disease modeling.
Cytoskeleton Crew
Findings confirm sugar's role in helping cancers survive by changing cellular architecture.
Biomarker for Recurring HPV-Linked Oropharyngeal Cancers
A look-back analysis of HPV infection antibodies in patients treated for oropharyngeal (mouth and throat) cancers linked to HPV infection suggests at least one of the antibodies could be useful in identifying those at risk for a recurrence of the cancer, say scientists at the Johns Hopkins University.
Valvena, GSK Sign New R&D Collaboration
Valneva to supply process development services for EB66® -based Influenza vaccines.
Light Signals from Living Cells
Fluorescent protein markers delivered under high pressure.
Cellular 'Relief Valve'
A team led by scientists at The Scripps Research Institute (TSRI) has solved a long-standing mystery in cell biology by showing essentially how a key “relief-valve” in cells does its job.
SELECTBIO

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,900+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,200+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!