Corporate Banner
Satellite Banner
Biomolecular Screening
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Autoclave Sealing Parts Withstand 4 Months Aggressive In-situ Testing

Published: Friday, October 18, 2013
Last Updated: Friday, October 18, 2013
Bookmark and Share
DuPont™ Kalrez® 6230 perfluoroelastomer seals from Dichtomatik.

Autoclaves are widely used to sterilize equipment with high pressure saturated steam at temperatures of 121°C or more. These conditions can be maintained for 15 to 20 minutes, depending upon the size of the system load and the contents.

Pressurized, high temperature steam is, however, one of the most aggressive operating environments, but this is necessary to achieve the high level of operating sterility and purity within the autoclave.

In between system loads, autoclaves are also subject to continuous cleaning cycles at high pressure/temperature steam conditions.

Typical autoclave applications include pharmaceuticals, microbiology, medicine, veterinary and mycology sciences, together with dentistry and general laboratories.

A growing application covers the pre-disposal treatment and sterilization of waste material, including pathogenic hospital waste to neutralize potentially infectious agents.

Because of such challenging applications, it is of paramount importance that autoclave components withstand the operating conditions.

Autoclaves can contain in excess of 200 seals that need to maintain their performance in hot pressurized saturated steam, as well as also being FDA and USP Class VI compliant.

The DuPont™ Kalrez® 6230 perfluoroelastomer (FFKM) seals have been developed to meet such unique requirements while providing excellent sealing qualities to comply with modern pharmaceutical processes.

These products are available from the UK authorized distributor Dichtomatik Ltd, and reduce extractables to trace levels while providing excellent steam cycling resistance up to 260°C.

Where in-situ tests have been conducted with saturated steam at 4 bar pressure and 140°C temperature, the Kalrez® 6230 seal parts performed well over a 4 month test duration of 8 hours per day and 5 days per week.

At the end of the test period, the seals exhibited little or no cracks and only minor compression set when compared to competitive perfluoroelastomer (FFKM and FKM) materials.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,300+ scientific posters on ePosters
  • More than 4,900+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.


Scientific News
Liquid Biopsies: Miracle Diagnostic or Next New Fad?
Thanks to the development of highly specific gene-amplification and sequencing technologies liquid biopsies access more biomarkers relevant to more cancers than ever before.
Mutations in DNA-Repair Genes Found in Advanced Prostate Cancers
New findings indicate that nearly 12% of male advanced prostate cancer sufferers have inherited mutation in DNA-repair genes.
Molecule May Affect Gaucher, Parkinson's Disease
Research has identified a molecule that restores activity of a dysfunctional enzyme linked to Gaucher and Parkinson's disease.
Targeting BRAF Mutations in Thyroid Cancer
Treating metastatic thyroid cancer patients harboring a BRAF mutation with vemurafenib showed anti-tumor activity in a third of patients.
Plant Compounds Fight Together Against Colon Cancer
Research shows treating colon cancer cells with curcumin, then silymarin is more effective than treatment with each individually.
New Centre Offers Ultra-Speed Protein Analysis
UW-Madison researchers to establish development centre for next-gen protein measurement technologies.
Drug Candidates Reduce Abnormal Protein Production
New drug candidates improve cell ability to catch miss-folded proteins that could cause deadly diseases.
Supercomputing and Drug Discovery
New biotech company uses supercomputer simulations to speed up drug discovery and biotech molecule development.
Preventing Breast Cancer with Hops
Study of hops extract suggests prevention of breast cancer through chemical pathway activation.
Treatment Advancement for Gaucher and Parkinson's Diseases
NIH scientists identify molecule that may act as a possible treatment of neurological diseases.
SELECTBIO

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,300+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,900+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!