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High magnification micrograph of microglia cells stained with Rio-Hortega's method (silver carbonate). This type is the ramified or resting microglia that appears in normal brain tissue.
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Mobilizing Microglia in the Fight Against Alzheimer’s Disease

Recently approved Alzheimer's drugs work by tagging amyloid plaques for clearance by the brain's microglia. Washington University School of Medicine in St. Louis researchers are developing an alternative approach, using a homemade antibody to directly mobilize microglia.
Cancer cells.
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Immunotherapy After Kidney Cancer Surgery Improves Overall Survival

For the first time in fifty years, results from a phase 3 randomized, placebo-controlled trial have shown an overall survival benefit from an adjuvant therapy in patients with kidney cancer.
The outline of a person and their brain facing a cannabis leaf and symbolic CBN pill.
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Cannabinols Show Neuroprotective Properties in Fruit Flies

Salk scientists observe cannabinol's neuroprotective properties in fruit flies and identify cannabinol analogs that could serve as promising future therapeutics for traumatic brain injury, Alzheimer's, and Parkinson's.
A purple human brain.
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Antipsychotic Use in Dementia Linked to Elevated Health Risks

Antipsychotic use in people with dementia is associated with elevated risks of a wide range of serious adverse outcomes including stroke, blood clots, heart attack, heart failure, fracture, pneumonia, and acute kidney injury, compared with non-use.
Umbrella-shaped antibacterial toxin particles drifting toward and engaging a bacterial target cell.
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Soil Bacteria Produce Unique Antimicrobial Particles

Researchers have discovered toxic protein particles, shaped like umbrellas, that soil bacteria known as Streptomyces secrete to squelch competitors, especially others of their own species.
A scientist pipetting into an assay plate.
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AI Method Accelerates Drug Discovery for Parkinson’s 10-Fold, Study Finds

University of Cambridge researchers have harnessed the power of artificial intelligence (AI) to speed up the screening of new drugs to treat Parkinson’s disease.
HIV attacking a human cell.
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Study Investigates Links Between HIV Drugs and Reduced Alzheimer’s Disease Incidence

Alzheimer’s disease (AD) currently afflicts nearly seven million people in the U.S. Scientists at Sanford Burnham Prebys have now identified promising real-world links between common HIV drugs and a reduced incidence of AD.
A plastic model of the human brain, bisected.
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Scientists Pinpoint Brain Region Crucial for Attention Control

Researchers have linked a region in the brain to how humans redirect thoughts and attention when distracted, offering insights into side effects of Parkinson's disease treatment.
A bag of medication hanging on a drip stand.
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Targeted Liver Cancer Treatment May Help Cut Side Effects

3D-printed films loaded with drugs could be used to kill cancer cells while minimizing the toxicity of traditional chemotherapy.
Green and teal capsules spill from a prescription bottle.
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Dementia Drug Doesn’t Increase Risk of Death or Fatal Heart Condition, Study Finds

Contrary to past warnings, a new study has found that a commonly prescribed dementia drug doesn't increase the risk of death or heart rhythm problems.
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