"The Axon Digidata® 1440A Digitizer is a low-noise high-resolution 16-bit data acquisition system for electrophysiology recordings. It is self-contained and communicates with the host computer via a USB 2.0 interface for extremely easy installation and setup. Designed for fast results, the Digidata 1440A Digitizer comes with AxoScope software for Microsoft Windows OS and is ready to acquire data immediately after installation. Absolutely no programming is necessary.
The Digidata 1440A Digitizer features a maximum sampling rate of 250 kHz per channel, with an outstanding total data throughput rate of 4 mega-samples per second. This enables you to capture even the fastest signals in the biorelevant frequency range. Both the inherent digitizer noise and channel crosstalk noise are rated at less than ±1 mV average p-p at 10 kHz, within a ±10 V input range, making the Digidata 1440A System one of the quietest digitizers on the market.
For intuitive setup, the front panel is clearly laid out with sixteen analog input channels and four analog output channels, eight general digital outputs, one dedicated digital output to trigger devices such as oscilloscopes, as well as trigger inputs to start acquisition and to tag data. The back panel has four additional analog instrument telegraph inputs, as well as a DB-25 connector for the digital outputs."
Charting Kidney Cancer Metabolism Changes in cell metabolism are increasingly recognized as an important way tumors develop and progress, yet these changes are hard to measure and interpret. A new tool designed by MSK scientists allows users to identify metabolic changes in kidney cancer tumors that may one day be targets for therapy.Insights into the Function of the Main Class of Drug Targets About thirty percent of all medical drugs such as beta-blockers or antidepressants interact with certain types of cell surface proteins called G protein coupled receptors.Visualizing a Cancer Drug Target at Atomic Resolution Using cryo-electron microscopy, researchers were able to view, in atomic detail, the binding of a potential small molecule drug to a key protein in cancer cells.Honey’s Potential to Save Lives The healing powers of honey have been known for thousands of years. 3-D Printed Lifelike Liver Tissue for Drug Screening A team led by engineers at the University of California, San Diego has 3D-printed a tissue that closely mimics the human liver's sophisticated structure and function. The new model could be used for patient-specific drug screening and disease modeling. Cytoskeleton Crew Findings confirm sugar's role in helping cancers survive by changing cellular architecture.Biomarker for Recurring HPV-Linked Oropharyngeal Cancers A look-back analysis of HPV infection antibodies in patients treated for oropharyngeal (mouth and throat) cancers linked to HPV infection suggests at least one of the antibodies could be useful in identifying those at risk for a recurrence of the cancer, say scientists at the Johns Hopkins University. Valvena, GSK Sign New R&D Collaboration Valneva to supply process development services for EB66® -based Influenza vaccines. Light Signals from Living Cells Fluorescent protein markers delivered under high pressure.Cellular 'Relief Valve' A team led by scientists at The Scripps Research Institute (TSRI) has solved a long-standing mystery in cell biology by showing essentially how a key “relief-valve” in cells does its job.