Corporate Banner
Satellite Banner
Biomolecular Screening
Scientific Community
 
Become a Member | Sign in
Home>Products>This Product
  Products


MaxDiscovery™ Human IL-1ß ELISA Test Kit

Product Description
The MaxDiscovery™ Human IL-1ß ELISA Test Kit is designed for quantitative determination of the concentration of human IL-1ß in serum, plasma, and cell culture supernatant. Human interleukin 1ß (IL-1ß) is a 17 kDa protein which is produced by various cells. IL-1ß has multiple functions including local inflammation. Following bacterial or immunoglobulin ligation of monocyte/macrophage CD14 (the LPS receptor) 17 or CD64 (the IgG receptor), IL-1ß can be released into a local environment. Within this environment, IL-1ß impacts a number of cells, facilitating mononuclear infiltration into an area of early inflammation. IL-1ß also induces expression of itself in newly arriving monocytes. In terms of other pro-inflammatory molecules, IL-1ß apparently is needed for the efficient production of IFN-?. On resident NK cells, IL-1ß apparently works in conjunction with macrophage-derived IL-12 to induce IFN-? secretion, resulting in an IFN-? induced activation of macrophages. Finally, IL-1ß also induces the expression of MMPs from resident fibroblasts. This can have at least two effects: first extracellular matrix degradation can facilitate monocyte migration, and second, MMPs are known to degrade IL-1ß, thus down-modulating the local inflammatory response initiated by IL-1. Selected References: Chiang, C.Y. et al (Nov. 2010) Fiber-optic particle plasmon resonance sensor for detection of interleukin-1ß in synovial fluids Biosensors and Bioelectronics, 26 (3), p.1036. doi:10.1016/j.bios.2010.08.047.
Product MaxDiscovery™ Human IL-1ß ELISA Test Kit
Company BIOO Scientific - Product Directory
Price Request a quote
More Information View company product page
Catalog Number 2110-01
Quantity 1 x 96 wells
Company Logo

BIOO Scientific - Product Directory
3913 Todd Lane Suite 312 Austin, TX 78744, USA

Tel: +1 512-707-8993
Fax: +1 512-707-8122
Email: info@biooscientific.com



Scientific News
Gene Terapy for Muscle Wasting Developed
New gene therapy could save millions of people suffering from muscle wasting disease.
Detecting Alzheimer's with Smell Test
Odour identification test may offer low-cost alternative for predicting cognitive decline and detecting early-stage Alzheimer’s disease.
Fighting Cancer Through Protein Pathways
Researchers have found a new drug target within a protein production pathway critical to regulating growth and proliferation of cells.
Mutations in DNA-Repair Genes Found in Advanced Prostate Cancers
New findings indicate that nearly 12% of male advanced prostate cancer sufferers have inherited mutation in DNA-repair genes.
Molecule May Affect Gaucher, Parkinson's Disease
Research has identified a molecule that restores activity of a dysfunctional enzyme linked to Gaucher and Parkinson's disease.
Targeting BRAF Mutations in Thyroid Cancer
Treating metastatic thyroid cancer patients harboring a BRAF mutation with vemurafenib showed anti-tumor activity in a third of patients.
Plant Compounds Fight Together Against Colon Cancer
Research shows treating colon cancer cells with curcumin, then silymarin is more effective than treatment with each individually.
New Centre Offers Ultra-Speed Protein Analysis
UW-Madison researchers to establish development centre for next-gen protein measurement technologies.
Drug Candidates Reduce Abnormal Protein Production
New drug candidates improve cell ability to catch miss-folded proteins that could cause deadly diseases.
Supercomputing and Drug Discovery
New biotech company uses supercomputer simulations to speed up drug discovery and biotech molecule development.

SELECTBIO

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,300+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,900+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!