The MaxDiscovery™ Human MCP-1 ELISA Test Kit is designed for quantitative determination of the concentration of human MCP-1 in serum, plasma, and cell culture supernatant. Mature human monocyte chemotactic protein-1 (MCP-1) is a polypeptide of 76 amino acids after cleavage of a signal peptide of 23 amino acids from the precursor of 99 amino acids. It is a member of the C-C family of chemokines. Chemokines are mediators that share the capacity to induce directional migration of leukocytes. MCP-1 is a chemoattractant for many cell types such as monocytes, neutrophilis, hepatic stellar cells, granulocytes and T lymphocytes. MCP-1 is believed to play a role in a variety of pathological conditions, including inflammatory and immune reactions, atherosclerosis and neoplasia. MCP-1 is also known as Monocyte Chemostatic Activating Factor (MCAF) or CCL2.