Corporate Banner
Satellite Banner
Biomolecular Screening
Scientific Community
Become a Member | Sign in
Home>Products>This Product

MaxDiscovery™ Human Survivin ELISA Test Kit

Product Description
The MaxDiscovery™ Human Survivin ELISA Test Kit is designed for quantitative determination of the concentration of human Survivin in serum, plasma, and cell culture supernatant. Human survivin, also known as baculoviral IAP repeat-containing protein 5 (BIRC5) and apoptosis inhibitor 4 (API4), is an approximately 34 kDa protein which contains a single baculovirus IAP repeat (BIR) domain and an extended carboxy-terminal a-helical coil that forms a bowtie-shaped homodimer. It has at least two functions, the regulation of cell division and the suppression of apoptosis. Therefore, survivin may play a role in tumor formation and tumor cell resistance to anti-cancer agents. Survivin expression is regulated in a cell cycle-dependent manner. As a component of the chromosomal passenger complex (CPC), survivin has been implicated in the regulation of several mitosis-related events including chromosome alignment, histone modification, and cytokinesis. In addition to its role as a mitotic regulator, survivin also functions as an inhibitor of apoptosis by suppressing cell death initiated by both the intrinsic and extrinsic apoptosis pathways. Since survivin is dramatically over-expressed in many cancers and the expression in these tumors can correlate with an increased rate of tumor recurrence and resistance to therapy, the presence of survivin in urine may also act as a marker for bladder cancer.
Product MaxDiscovery™ Human Survivin ELISA Test Kit
Company BIOO Scientific - Product Directory
Price Request a quote
More Information View company product page
Catalog Number 2136
Quantity 1 x 96 wells
Company Logo

BIOO Scientific - Product Directory
3913 Todd Lane Suite 312 Austin, TX 78744, USA

Tel: +1 512-707-8993
Fax: +1 512-707-8122

Scientific News
Influential Cancer Researcher Receives Agilent Thought Leader Award
Biologist Scott Lowe receives award in recognition for his contributions to cancer biology.
Startup Seeks More Precise Prostate Cancer Screening
Gregor Diagnostics aims to bring a non-invasive prostate cancer screening test to the market.
Tumor Markers Reveal Lethality Of Bladder Cancers
Researchers found that detection of certain tumor cells in early stage cancers helps identify high-risk cancers.
Preventing "Friendly Fire" in the Pancreas
Researchers inhibit process that leads to the body attacking its own insulin-producing cells.
Drug Target for Triple-Negative Breast Cancer Found
A team of researchers led by UC San Francisco scientists has identified a new drug target for triple-negative breast cancer.
3D-Printed Heart-On-A-Chip with Integrated Sensors
Researchers have created the first 3D-printed organ-on-a-chip with integrated sensors, paving the way for more complex, customizable devices.
Smartphone Laboratory Detects Cancer
Researchers develop low-cost, portable laboratory on a smartphonecapable of analysing multiple samples simultaneously.
First Entirely 3D-printed Organ-on-a-Chip with Integrated Sensors
New approach to manufacturing may allow researchers to rapidly design organs-on-chips that match the properties of a specific disease or individual patient's cells.
Targeting Cannabinoid CB2 Receptors in the CNS
With endogenous cannabinoids considered as a potential target to combat CNS diseases, this article examines the role of CB2R could play in fighting some disorders.
Bacterial Genes Boost Current in Human Cells
Borrowing and tweaking bacterial genes to enhance electrical activity might treat heart, nervous system injury.

Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,500+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
5,200+ scientific videos