Corporate Banner
Satellite Banner
Biomolecular Screening
Scientific Community
 
Become a Member | Sign in
Home>Products>This Product
  Products


MaxDiscovery™ Human Survivin ELISA Test Kit

Product Description
The MaxDiscovery™ Human Survivin ELISA Test Kit is designed for quantitative determination of the concentration of human Survivin in serum, plasma, and cell culture supernatant. Human survivin, also known as baculoviral IAP repeat-containing protein 5 (BIRC5) and apoptosis inhibitor 4 (API4), is an approximately 34 kDa protein which contains a single baculovirus IAP repeat (BIR) domain and an extended carboxy-terminal a-helical coil that forms a bowtie-shaped homodimer. It has at least two functions, the regulation of cell division and the suppression of apoptosis. Therefore, survivin may play a role in tumor formation and tumor cell resistance to anti-cancer agents. Survivin expression is regulated in a cell cycle-dependent manner. As a component of the chromosomal passenger complex (CPC), survivin has been implicated in the regulation of several mitosis-related events including chromosome alignment, histone modification, and cytokinesis. In addition to its role as a mitotic regulator, survivin also functions as an inhibitor of apoptosis by suppressing cell death initiated by both the intrinsic and extrinsic apoptosis pathways. Since survivin is dramatically over-expressed in many cancers and the expression in these tumors can correlate with an increased rate of tumor recurrence and resistance to therapy, the presence of survivin in urine may also act as a marker for bladder cancer.
Product MaxDiscovery™ Human Survivin ELISA Test Kit
Company BIOO Scientific - Product Directory
Price Request a quote
More Information View company product page
Catalog Number 2136
Quantity 1 x 96 wells
Company Logo

BIOO Scientific - Product Directory
3913 Todd Lane Suite 312 Austin, TX 78744, USA

Tel: +1 512-707-8993
Fax: +1 512-707-8122
Email: info@biooscientific.com



Scientific News
Automated Patch Clamping Trends
Learn more about current practices, preferences and metrics in ion channel drug screening using APC technology.
Fly Study into Therapies for HVP-Induced Cancer
Fruit flies may help scientists understand the mechanism by which HPV can cause cancer as well as identify potential drug treatments.
World's Most In-Depth Study to Detect Alzheimer's Disease
A multisite team will see the most thorough and vigorous testing for Alzheimer's ever performed on volunteers.
'Missing Evolutionary Link' of Natural Drug Source Found
Scripps Florida study finds 'missing evolutionary link' of a widely used natural drug source
Grad Student's Finding Enables Rapid Compound Screening
Grad student makes technical leap that could enable rapid screening of anti-cancer compounds.
Uncovering Constructor Proteins
Scientists have discovered a new bacterial cell wall builder that could be a target for antibiotic development.
Cholesterol Linked to Aggressive Cancers
Research suggests fats, such as cholesterol, can increase aggressive cancer progression.
Biomarker Breakthrough Could Improve Parkinson’s Treatment
A new method of tracking Parkinson's progression could aid evaluation of new and experimental treatments to slow or stop the disease.
Targeting Neglected Diseases
New enzyme-mapping advancement could help drug development for combating diseases in the developing world.
How Parkinson’s Disease Alters Brain Activity Over Time
The NIH study provides a new tool for testing experimental medications aimed at alleviating symptoms and slowing the rate at which the diseases damage the brain.

SELECTBIO

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,300+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
5,000+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!