Corporate Banner
Satellite Banner
Biomolecular Screening
Scientific Community
 
Become a Member | Sign in
Home>Products>This Product
  Products


MaxDiscovery™ Mouse IL-5 ELISA Test Kit

Product Description
The MaxDiscovery™ Mouse IL-5 ELISA Test Kit is designed for quantitative determination of the concentration of mouse IL-5 serum, plasma, and cell culture supernatant. Mature mouse interleukin 5 (IL-5) is a 12 kDa protein consisting of 113 amino acids and is processed from a 133 amino acid precursor. IL-5 is mainly generated in T cells as a disulfide-linked homodimeric 40-45 kDa glycoprotein. The homodimer is formed by two interchain disulfide bonds between Cys 44 and 86 of each chain. T cell derived IL-5 appears to be the main cytokine involved in the control of eosinophilia. The effects of IL-5 on eosinophils include promoting growth and differentiation, activating mature eosinophils and increasing the survival of these cells during parasitic infection. In mice, IL-5 acts on B cells to induce differentiation into Ig-producing cells. The critical role of the eosinophils in allergy indicates that IL-5 is a key cytokine in the development of allergic diseases such as asthma. There is 71% homology between human and mouse IL-5 and significant crossreactivity in functional assays. Murine IL-5 receptor (IL-5R) consists of an a and ß polypeptide chain. The IL-5R a chain is a 60 kDa protein with a low binding affinity for IL-5. Association with the 130 kDa IL-5R ß chain increases the binding affinity for IL-5 aprroximately 100-fold, although the ß chain does not bind IL-5 by itself.
Product MaxDiscovery™ Mouse IL-5 ELISA Test Kit
Company BIOO Scientific - Product Directory
Price Request a quote
More Information View company product page
Catalog Number 2007-01
Quantity 1 x 96 wells
Company Logo

BIOO Scientific - Product Directory
3913 Todd Lane Suite 312 Austin, TX 78744, USA

Tel: +1 512-707-8993
Fax: +1 512-707-8122
Email: info@biooscientific.com



Scientific News
Insights into the Function of the Main Class of Drug Targets
About thirty percent of all medical drugs such as beta-blockers or antidepressants interact with certain types of cell surface proteins called G protein coupled receptors.
Visualizing a Cancer Drug Target at Atomic Resolution
Using cryo-electron microscopy, researchers were able to view, in atomic detail, the binding of a potential small molecule drug to a key protein in cancer cells.
Honey’s Potential to Save Lives
The healing powers of honey have been known for thousands of years.
3-D Printed Lifelike Liver Tissue for Drug Screening
A team led by engineers at the University of California, San Diego has 3D-printed a tissue that closely mimics the human liver's sophisticated structure and function. The new model could be used for patient-specific drug screening and disease modeling.
Cytoskeleton Crew
Findings confirm sugar's role in helping cancers survive by changing cellular architecture.
Biomarker for Recurring HPV-Linked Oropharyngeal Cancers
A look-back analysis of HPV infection antibodies in patients treated for oropharyngeal (mouth and throat) cancers linked to HPV infection suggests at least one of the antibodies could be useful in identifying those at risk for a recurrence of the cancer, say scientists at the Johns Hopkins University.
Valvena, GSK Sign New R&D Collaboration
Valneva to supply process development services for EB66® -based Influenza vaccines.
Light Signals from Living Cells
Fluorescent protein markers delivered under high pressure.
Cellular 'Relief Valve'
A team led by scientists at The Scripps Research Institute (TSRI) has solved a long-standing mystery in cell biology by showing essentially how a key “relief-valve” in cells does its job.
Genomic Signature Shared by Five Types of Cancer
National Institutes of Health researchers have identified a striking signature in tumor DNA that occurs in five different types of cancer.

SELECTBIO

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,900+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,200+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!