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MaxDiscovery™ Rat TNF-a ELISA Test Kit

Product Description
The MaxDiscovery™ Rat TNF-a ELISA Test Kit is designed for quantitative determination of the concentration of rat TNF-a in serum, plasma, and cell culture supernatant. Rat tumor necrosis factor-alpha (TNF-a) is primarily a homotrimeric 17 kDa protein, a potent mediator of inflammatory and metabolic functions. Originally known as a highly cytotoxic cytokine for tumor cells, it is produced by lipopolysaccharide stimulated macrophages. When injected into tumor bearing animal, it causes tumor necrosis in vivo and shows cytolytic activity against tumor cells in vitro. Further, TNF-a has been implied as central mediator in shock induced by gram negative microorganisms. TNF-a functions as a central mediator in many inflammatory and immunological processes. Interestingly, it also induced on its turn the production of many cytokines. Signal transduction occurs via two types of TNF-receptors, the p55 and p75 TNF-receptors. The receptors differ strongly in their intracellular signaling pathways.
Product MaxDiscovery™ Rat TNF-a ELISA Test Kit
Company BIOO Scientific - Product Directory
Price Request a quote
More Information View company product page
Catalog Number 2203-01
Quantity 1 x 96 wells
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BIOO Scientific - Product Directory
3913 Todd Lane Suite 312 Austin, TX 78744, USA

Tel: +1 512-707-8993
Fax: +1 512-707-8122
Email: info@biooscientific.com



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