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Promising Class of New Cancer Drugs Cause Memory Loss in Mice
New findings from The Rockefeller University suggest that the original version of BET inhibitors causes molecular changes in mouse neurons, and can lead to memory loss in mice that receive it.
Electrical Control of Cancer Cells
Research led by scientists at The University of Texas Health Science Center at Houston (UTHealth) has revealed a new electrical mechanism that can control these switches.
Signature of Microbiomes Linked to Schizophrenia
Studying microbiomes in throat may help identify causes and treatments of brain disorder.
Inflammation Linked to Colon Cancer Metastasis
A new Arizona State University research study led by Biodesign Institute executive director Raymond DuBois has identified for the first time the details of how inflammation triggers colon cancer cells to spread to other organs, or metastasize.
Structural Discoveries Could Aid in Better Drug Design
Scientists have uncovered the structural details of how some proteins interact to turn two different signals into a single integrated output.
Determining the Age of Fingerprints
Watch the imprint of a tire track in soft mud, and it will slowly blur, the ridges of the pattern gradually flowing into the valleys. Researchers have tested the theory that a similar effect could be used to give forensic scientists a way to date fingerprints.
Genetic Overlapping in Multiple Autoimmune Diseases May Suggest Common Therapies
CHOP genomics expert leads analysis of genetic architecture, with eye on repurposing existing drugs.
Surprising Mechanism Behind Antibiotic-Resistant Bacteria Uncovered
Now, scientists at TSRI have discovered that the important human pathogen Staphylococcus aureus, develops resistance to this drug by “switching on” a previously uncharacterized set of genes.
Tissue Bank Pays Dividends for Brain Cancer Research
Checking what’s in the bank – the Brisbane Breast Bank, that is – has paid dividends for UQ cancer researchers.
Researchers Publish Landmark “Basket Study”
Researchers from Memorial Sloan Kettering Cancer Center (MSK) have announced results from the first published basket study, a new form of clinical trial design that explores responses to drugs based on the specific mutations in patients’ tumors rather than where their cancer originated.

Investigating the Kinetics of cAMP Accumulation in Human Primary Cells Using a Live-Cell cAMP Biosensor
Elizabeth Rosethorne, Novartis, speaking at Advances in Biosensors and Biodetection.

Modifying Cell Lines for Target Discovery and Validation
In this 30-minute seminar, we will discuss the process of genome editing, address factors affecting the design of a genome editing project, and explore the application of modified cell lines for target discovery and validation.

Strategies for the Identification of Lead Molecules to Sustain a Discovery Organisation
Steve Rees, AstraZeneca, speaking at Drug Discovery and Development 2014

Machine Learning for Building Models of Cell Perturbation
Robert Murphy, Carnegie Mellon University, speaking at Drug Discovery and Development 2014

Kinases as Targets for Drug Discovery in an Academic Setting
William Janzen,The University of North Carolina at Chapel Hill, speaking at Drug Discovery and Development 2014

Balancing Leverage with Stewardship of a Corporate Compound Collection
Rose Gonzales, Pfizer Global R&D, speaking at Drug Discovery and Development 2014

Heterogeneity of Cellular Responses to Perturbagens in Drug Discovery and Development
Lansing Taylor, University of Pittsburgh, speaking at Drug Discovery and Development 2014

Repurposing Approaches for Rare and Neglected Tropical Diseases
John Mckew, National Institutes of Health, speaking at Drug Discovery and Development 2014

Pivot Park Screening Centre, The Pivot for Screening Knowledge and Expertise
Helma Rutjes, Pivot Park Screening Centre, speaking at Drug Discovery and Development 2014

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