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Scientific News
Direct Drug Screening Of Biopsies Could Overcome Resistance
Combining genetic with pharmacologic screening of tumors may enable truly individualized treatment regimens.
Almac Announces Launch of CLIA Validated Next Generation Sequencing Assay
P53 considered important biomarker for cancer drug discovery.
Next-Gen Melanoma Drug Excels in Lab Tests
Anti-cancer activity was reported in 10 out of 11 patient tumor samples grown in mice and treated with the experimental drug TAK-733.
Blood Test Could Reduce Antibiotic Use
A new blood biomarker test that indicates whether bacteria is the cause of a patient’s lung infection is now being studied at UPMC Presbyterian.
New Targets and Test to Develop Treatments for Memory Disorders
The study focuses on kinesin, a molecular motor protein that plays a role in the transport of other proteins throughout a cell.
Drugging the Undruggable
Discovery opens up possibility of slowing cancer spread.
Classification of Gene Mutations in Neuroblastoma
Penn Medicine and CHOP experts define riskier mutations in neuroblastoma, setting stage for clinical trial.
Microscopic “Walkers” Find Their Way Across Cell Surfaces
Technology could provide a way to deliver probes or drugs to cell structures without outside guidance.
Study Investigates Inherent Contamination in Deep Well Microplates
Study gives data on microplates from numerous manufacturers based in Europe, USA and China.
Culture System Replicates Course Of Alzheimer’s Disease
Three-dimensional system should significantly reduce time and costs of drug development.

Capacitive Immunosensors – A Tool for Detection Where Sensitivity of Conventional ELISA is Not Sufficient
Prof. Bo Mattiasson, Lund University, speaking at Advances in Biodetection and Biosensors 2012.

Rationalizing ADME in the Current Regulatory and Business Environment
Robert Guttendorf, Aclairo Pharmaceutical Development Group, speaking at ADME & Predictive Toxicology Europe

Fragment-Based Screening and Structure-Based Design at ICR: Discovering High Quality Leads in Cancer Drug Discovery
Rob Van Montfort, Institute of Cancer Research, speaking at Discovery Chemistry Conference 2012.

Improvement of Cell Culture Technology for Primary Cells and Stem Cell Manipulation
Dr Veit Bergendahl, Miltenyi Biotec GmbH, speaking at Cell Culture 2012

Biotransformation: Still a Bottleneck for in Vitro Kinetic and Dynamic Approaches
Sandra Coecke, European Centre for the Validation of Alternative Methods, speaking at ADME & Predictive Toxicology Europe

Analysis of Cellular Image-based RNAi Screens Beyond Human Vision
Professor Frederic Bard, Institute of Molecular and Cell Biology, speaking at Screening Asia 2011.

Functional Interrogation of 'omics' Data
Dr Kartiki V Desai, National Insitute of Biomedical Genomics, speaking at Screening Asia 2011.

Understanding Fat Metabolism at the Organism Level – A Comprehensive Metabolic Screen of C. elegans.
Dr Jules Griffin, University of Cambridge, speaking at Advances in Metabolic Profiling 2011.

Actionable Biomarkers for Rheumatoid Arthritis
Dr William Robinson, Stanford University, speaking at Microarray World Congress 2011.

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