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Latest Articles

MALDI Imaging Mass Spectrometry (MALDI IMS): A Marriage of Mass Spectrometry and Morphological Spatial Resolution
Article

Matrix-assisted laser desorption/ionization imaging mass spectrometry (MALDI IMS) is a powerful analytical technique that enjoys the sensitivity of mass spectrometry coupled with spatial distribution information.

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Three Ways to Turn Life Science Suppliers into Partners
Article

A growing number of life science businesses are turning to greater supply chain collaboration for benefits like accelerated time to market, improved quality, reduced risk and more rapid and widespread innovation. But while 68% of executives in this industry say active and meaningful engagement with suppliers is essential to success, far too many, over a third, struggle to implement it.

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Host Cell Protein Analysis in Biopharma
Article

Presence of host cell protein (HCP) contaminants in the final product, even at very low levels, may elicit unpredictable and serious immunogenic response in humans. The accurate detection, identification and quantification of HCPs during biotherapeutic development is thus critical in ensuring patient safety, and is a regulatory requirement.

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Antimicrobial Resistance – the Rise of Global Superbugs
Article

Antimicrobials have revolutionized medicine by enabling treatments for diseases that would once have proven fatal, however,they have since proven to be a double-edged sword.

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Lytic vs Lysogenic – Understanding Bacteriophage Life Cycles
Article

Bacteriophage (phage) are obligate intracellular viruses that specifically infect bacteria. Here we take an overview of their structure, life-cycle and the role they have played in advancing science and medicine.

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The Agricultural Perspective on Water Contamination by Pharmaceuticals
Article

Despite centuries of research into drug development, investigation into the environmental impact of pharmaceuticals is a much younger field. If not treated effectively, there is the potential for pharmaceuticals in wastewater to affect the agricultural industry through the use of this contaminated water supply.

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Current Trends in Bispecifics, Dual-action and Combination Therapies
Article

It’s becoming increasingly apparent that treatments for complex diseases such as cancer, neurodegenerative diseases and depression are unlikely to target a single molecule in the pathological pathway. Drug developers are turning to new ways to exploit more than one drug target at a time.

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One-Way vs Two-Way ANOVA: Differences, Assumptions and Hypotheses
Article

A key statistical test in research fields including biology, economics and psychology, Analysis of Variance (ANOVA) is very useful for analyzing datasets. It allows comparisons to be made between three or more groups of data. Here, we summarize the key differences between these two tests, including the assumptions and hypotheses that must be made about each type of test.

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Biosafety and the Agents of Doom
Article

To combat harmful pathogens it is vitally important that scientists have facilities available that enable them to work on them safely. These facilities should prevent the operator from becoming infected with the agent they are working with and prevent the organism from escaping the laboratory setting and potentially initiating new outbreaks of disease.

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Cell Culture Quality Control: Blissful Ignorance?
Article

How can quality control efforts keep up with the rapid advances in cellular model research? Read on for insights into challenges in recognizing and managing issues in cell culture quality control.

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