7 Days in Science – May 15, 2020
List May 15, 2020
The cerebral organoid in this image was produced by using human embryonic stem cells. The organ-like cell cultures consist of neural stem cells (green), progenitor cells (red) and nerve cells (white).
Credit: Daniel Gonzalez-Bohorquez, UZH
There have been many theories tabled with regard to why we are seeing hotspots of disease during the current COVID-19 pandemic. One theory that seems to be persisting is a link between poor air quality and an increased disease severity. But is this a causative link or just a coincidence?
Historically, medical knowledge was based on evidence collected from studies exclusively on men. The 1977 FDA guideline on “General considerations for the clinical evaluation of drugs” excluded women of child-bearing potential from taking part in the majority of early phase clinical research. However, during the 1980’s a task force on women’s health from the US Public Health Service recognized that general understanding of women’s health was severely lacking due to the exclusion of women in research. I recently had the pleasure of speaking with Namandje N. Bumpus, Ph.D, Associate Dean for Basic Research and Associate Professor of Medicine from Johns Hopkins to learn more about the different types of bias in drug development and how to tackle it.
A Deep Look Into COVID-19: Vaccines, Drugs and the Evolutionary Arms Race
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