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Under a high magnification of 7075X, this digitally-colorized, scanning electron microscopic image depicts a number of Gram-negative, rod-shaped, Escherichia coli bacteria.
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“Smart Microbe” Can Deliver Therapeutics to the Gut

Researchers have engineered a strain of the probiotic Escherichia coli to secrete therapeutic proteins and limit the development of colitis in a mouse model of inflammatory bowel disease.
A coral reef, with corals in many different colors and shapes.
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Viral Attacks on Coral Symbionts Intensify With Warming Oceans

A three-year study has shown that viral attacks on the photosynthetic algae that give corals their color increase during marine heat waves.
Elderly couple walking away from the camera down a tree-lines path, one with a stick, the other a shopping bag on wheels.
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Robust Immunity May Be Key to Centenarian's Longevity

Centenarians, a rare population of individuals who reach 100 years or more, experience delays in aging-related diseases and mortality which suggests their immune systems remain functional into extreme old age.
A hospital ward.
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Microbiome–Immune System Dysfunction Increases Infections in the Critically Ill

According to a study, high rates of infection in critically ill patients are linked with abnormalities of the microbiome and impaired immune system function.
Microscope images of cells from biopsies of melanoma patients that were treated or not with immune checkpoint blockade were stained for neutrophil activation. Left: Biopsy of an untreated patient, with white arrow showing neutrophils. Right: Biopsy of a patient treated with immunotherapy, with yellow arrows showing activated neutrophils.
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New Study Suggests Neutrophils Can Play Key Anti-Tumor Role

A new study suggests that neutrophils, a type of white blood cell, have an unappreciated role in eradicating solid tumors.
A glass of whisky
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Alcohol's Impact on the Brain Makes Us More Likely To Drink

Heavy alcohol use creates a vicious cycle: It changes signaling pathways in the brain, which in turn affects cognitive functions like decision-making and impulse control — and makes the individual more likely to drink.

Older couple embracing in a dancing pose.
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Harnessing Anti-Viral Immune Response Could Promote Healthy Aging

Scientists have found that the immune response to a virus that is ubiquitously present in human tissues can detect and eliminate senescent cells in the skin, a process that could restore tissue balance and lead to an increased healthy lifespan.
Red blood cells flow through a blood vessel.
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Substance Secreted by T Cells Impacts Blood Pressure and Inflammation

Researchers have discovered that a subset of T cells secrete acetylcholine, which helps to regulate blood pressure and inflammation.
Cells with transparent membranes and orange nuclei.
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Raman-Based Flow Cytometry Tool Boosts Understanding of Metabolism at Single-Cell Level

Researchers have developed a platform that improves accuracy, throughput and stability in profiling the dynamic metabolic features of cells.
Protein’s Shape Underpins Shigella Susceptibility content piece image
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Protein’s Shape Underpins Shigella Susceptibility

Shigella bacteria can infect humans but not mice. Now, a team from UConn Health explains why. Their findings may explain the multifariousness of a key weapon of our immune system.
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