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Gut Cells Act as Infection Sensors
Gut cells can use a "sense of touch" to detect harmful bacteria and then initiate an immune response.
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Plant Molecule Sops Up Iron-Rich Heme
According to a study, peptides in legume plants collect all available heme, sending bacteria into iron-starvation mode to increase ammonia production, the form of nitrogen useful for plants.
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At-Home Prototype Saliva Test Competes With RT-PCR
A prototype at-home test for SARS-CoV-2 that requires a non-invasive saliva sample has been shown to be comparable to RT-PCR in terms of specificity and sensitivity.
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Monoclonal Antibody Decreased Asthma Attacks in Urban Youth
A monoclonal antibody, mepolizumab, decreased asthma attacks by 27% in Black and Hispanic children and adolescents who have a form of severe asthma, are prone to asthma attacks and live in low-income urban neighborhoods, a National Institutes of Health clinical trial has found.
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New Antibiotic Candidate Fights Off Over 300 Drug-Resistant Bacteria
Researchers report a new molecule that inhibits drug-resistant bacteria in lab experiments, as well as in mice with pneumonia and urinary tract infections, which could one day be used to treat challenging infections in humans.
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Mystery “Jumping” Gene Helps Mice Survive Infections
A transposable element or "jumping" gene in mice has been shown to control the immune system in response to viral infection, promoting host survival.
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How Bacteria Defuse the Innate Immune System's Antimicrobial Weaponry
How do a wide variety of bacteria — both pathogenic and commensal — survive antimicrobials released by the mammalian innate immune system?
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Monkeypox Added to Wastewater Screening Panel
An ongoing program that monitors wastewater for the presence of SARS-CoV-2 and has effectively predicted subsequent surges in COVID-19 cases in San Diego has been expanded to detect the presence of monkeypox.
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Microbiome Molecule Can Induce Neuronal Inflammation
Research reports for the first time a pathway that begins in the gut and ends with a potent pro-inflammatory toxin in brain cells contributing to the development of Alzheimer’s disease (AD).
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Next-Generation Sequencing Compared to Standard of Care Diagnostics
According to a study, next-generation sequencing diagnostic systems enable clinicians to simultaneously sequence multiple strands of DNA found in patient samples and use that analysis to identify a single pathogen.
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