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HDAC6 Halts the Spread of Triple-Negative Breast Cancer
The genetic modifier HDAC6 was found to control tumor growth and halt metastasis in triple-negative breast cancer.
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Information on Over 200 Plant Viruses Provided by Brazilian Inventory
A Brazilian scientist has produced an inventory of 219 pathogens that infect plants in Brazil, including many agriculturally important species.
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Existing Alcoholism Drug Potentially Effective Against COVID-19
Chemists have used molecular modeling to identify two existing drugs that could be used to fight SARS-CoV-2. These are disulfiram, which is used to treat alcoholism, and neratinib, an experimental drug being used to treat breast cancer.
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Taste Bud Cells Might Not Be a Target of SARS-CoV-2
Initial data from a study in mice have suggested that SARS-CoV-2 may not actually target taste buds and therefore the symptom of taste loss might arise through other means.
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How Cells Keep Growing Even When Under Attack
In an unexpected new finding, biochemists at the University of Massachusetts Amherst report observing that a damage-containment system in stressed bacteria can become overrun and blocked, but that this leads to cells responding by turning on very different pathways to make sure that normal growth continues.
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Two Is Better Than One for Novel COVID-19 Mouse Model
Researchers have developed a new mouse model to study SARS-CoV-2 infection and disease and to accelerate testing of novel treatments and vaccines against the novel coronavirus.
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Embryos Could Be Susceptible to Coronavirus, Study Suggests
Genes that are thought to play a role in how the SARS-CoV-2 virus infects our cells have been found to be active in embryos as early as during the second week of pregnancy, say scientists at the University of Cambridge and the California Institute of Technology. The researchers say this could mean embryos are susceptible to COVID-19 if the mother gets sick, potentially affecting the chances of a successful pregnancy.
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Only Around 60% of Recovered COVID-19 Patients Develop Protective Antibodies
Scientists have found that only around 60% of patients who have had COVID-19 and recovered from it develop protective antibodies. They also showed that some antibodies even "assist" the virus in infecting host cells.
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NIH Announces Clinical Trial To Test Monoclonal Antibodies for COVID-19
A Phase 2 clinical trial will evaluate the safety and efficacy of potential new therapeutics for COVID-19, including an investigational therapeutic based on synthetic monoclonal antibodies (mAbs) to treat the disease.
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RLF-100 Trial Shows Rapid Recovery From Respiratory Failure in Critically Ill Patients With COVID-19
A clinical trial of RLF-100 (aviptadil) has shown rapid recovery from respiratory failure in critically ill patients with COVID-19.
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