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Could Heparin Be Used To Stop SARS-CoV-2 From Infecting Human Cells?
SARS-CoV-2 uses a surface spike protein to latch onto human cells and initiate infection. But, the drug heparin is capable of binding tightly to the same surface spike protein, potentially blocking the infection from happening.
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Breast Cancer Cells Disrupt Local Immune Defenses
Cold Spring Harbor Laboratory (CSHL) Associate Professor Mikala Egeblad and her colleagues describe a newly understood way by which breast cancer cells sabotage a key player in the body’s immune system.
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New Tools Increase Accuracy of CRISPR-based Edits
Biomolecular engineers have uncovered a technique that dramatically enhances the accuracy of CRISPR-based edits in disease sequence models.
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Once-daily Topical Treatment Improves Chronic Plaque Psoriasis
In Phase 2b clinical trials, a once-daily roflumilast cream showed significant improvements in psoriasis signs and symptoms, in as early as two weeks.
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Evidence of SARS-CoV-2 Transmission Across the Placenta
A study published in Nature Communications presented evidence of transplacental transmission of SARS-CoV-2 from an infected mother to her unborn child.
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Protein Provides a CRISPR “Kill Switch”
A single protein derived from a common strain of bacteria found in the soil will offer scientists a more precise way to edit RNA.
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Placenta Lacks Expression of Main Cell Entry Mediators for SARS-CoV-2
Researchers have found that placental cells minimally express the instructions, or mRNA, to generate the cell entry receptor and protease required by the virus that causes COVID-19 to invade human cells.
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Novel Test Method Detects SARS-CoV-2 in Highly Diluted Gargle Samples
Pharmacists at Martin Luther University Halle-Wittenberg have succeeded in detecting small amounts of SARS-CoV-2 using mass spectrometry and gargle solutions of COVID-19 patients.
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How Much Force Is Needed To Kill a Single Bacterium?
Researchers quantified the forces that cause critical damage on a single E. coli bacterium under physiological conditions using AFM nanoindentation and fluorescence imaging.
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COVID-19 and the Heart – A Pursuit for the SARS-CoV-2 Receptor
Using single nucleus sequencing technologies in human heart samples, researchers have established a potential mechanism for cardiac complications related to COVID-19.
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