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Webcasts
The Tip of the Iceberg - How Pipette Tips Influence Assay ResultsThe Tip of the Iceberg - How Pipette Tips Influence Assay Results
n this webinar, you will learn everything you need to know about pipette tips and the huge impact they can have on your results.
Subcellular fractionation and enrichment strategies for improved mass spectrometry analysisSubcellular fractionation and enrichment strategies for improved mass spectrometry analysis
In this webinar, you will learn how differential detergent subcellular fractionation can improve protein identification and be used to identify co-localizing proteins.

Market Reports
High Throughput Assay Trends 2015
HTStec Limited

This market report summarizes the results of HTStec’s industry-wide global web-based benchmarking survey on high throughput flow cytometry (HT flow) screening carried out in December 2014.
Mobile Technology In The Lab Trends 2015
HTStec Limited

This market report summarizes the results of HTStec’s industry-wide global web-based benchmarking survey on the use of mobile technology to monitor and control of lab instruments and automated systems carried out in April 2015.
Epigenetic Proteins & Reagents Trends 2015
HTStec Limited

This market report summarizes the results of HTStec’s industry-wide global web-based benchmarking survey on epigenetic proteins and reagents carried out in March 2015.
3D Spheroid Culture Trends 2015
HTStec Limited

This market report summarizes the results of HTStec’s industry-wide global web-based benchmarking survey on three dimensional (3D) spheroid culture carried out in May 2015.
Immunoassay Auto Trends 2014
HTStec

This report comprehensively documents current practices and preferences in immunoassays and to understand future user requirements, particularly with respect to immunoassay automation.
Cell-Based Label-Free Detection Trends 2014
HTStec Limited

This market report summarizes the results of HTStec’s 4th global web-based benchmarking survey on cell-based label-free (LF) detection carried out in July and August 2014. The study also examined in detail the current market landscape, application areas and interest in purchasing new products/systems.
HTS Metrics & Future Direction Trends 2014
HTStec

This market report summarizes the results of HTStec’s global web-based benchmarking survey on high throughput screening (HTS) metrics and future directions carried out in July 2014. The survey was initiated by HTStec as part of its tracking of life science marketplaces and to update our previous report (April 2012). It followed an approach from Pharma to benchmark recent HTS metrics.
Label-Free Binding Analysis Trends 2014
HTStec

This market report summarizes the results of HTStec’s 4th global web-based benchmarking survey on label-free (LF) binding analysis carried out in July 2014. The study was initiated by HTStec as part of its regular (every 2 years) tracking of this life science marketplace. The questionnaire was compiled to address the needs and interests of the LF binding analysis vendor community.
Epigenetic Modification Screening Trends 2014
HTStec

This market report summarizes the results of HTStec’s 3nd industry-wide global web-based benchmarking survey on epigenetic modification screening carried out in May 2014.
Multi-Channel Pipettor QC Trends 2014
HTStec

Multi-channel pipettors are essential tools in most life science laboratories today. Yet the impact of undertaking quality control (QC) measures on improving data quality, enhancing productivity/efficiency and reducing experimental failures has only relatively recently been recognized. Understanding how lab users approach the issue of pipettor QC is important as the industry struggles to adopt standards for automated pipetting.
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Scientific News
Featured Article
Big Genetics in BC: The American Society for Human Genetics 2016 Meeting
Themes at this year's meeting ranged from the verification, validation, and sharing of data, to the translation of laboratory findings into actionable clinical results.

Featured Article
Stem Cells in Drug Discovery
Potential Source of Unlimited Human Test Cells, but Roadblocks Remain.

Featured Article
Automated Low Volume Dispensing Trends
Gain a better understanding of the current and future market requirements for fully automated LVD systems.

Personality Traits, Psychiatric Disorders Linked to Specific Genomic Locations
Researchers have unearthed genetic correlations between personality traits and psychiatric disorders.
Forensic 3D Documentation of Skin Injuries
In this study, the validity of using photogrammetry for documenting injuries in a pathological context was demonstrated.
3-D Printed Dog’s Nose Improves Vapor Detection
By mimicking how dogs get their whiffs, a team of government and university researchers have demonstrated that “active sniffing” can improve by more than 10 times the performance of current technologies that rely on continuous suction to detect trace amounts of explosives and other contraband.
New Markers for Forensic Body-fluid Identification
University of Bonn researchers have successfully identified specific Micro-RNA signatures to help forensically identify body fluids.
Genetics Control Regenerative Properties Of Stem Cells
Researchers define how genetic factors control regenerative properties of blood-forming stem cells.
Major Neuroscience Initiative Launched
Tianqiao and Chrissy Chen Institute invest $115 million to further expand neuroscience research, while Caltech construct $200 million biosciences complex.
Making It Personal
Cancer vaccine linked to increased immune response against leukemia cells.
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Business News
NantHealth, Lunatus Collaborate
Collaboration aims to distribute NantHealth GPS cancer test in Middle East.
Recipharm, Laccure Collaborate
Collaboration aims to the commercial production of Laccure® Pessary.
Singulex, Thermo Fisher Announces Agreement
Agreement to bring next generation immunodiagnostics to sepsis and SIRS diagnostics.
Invitae, TME Research Collaborate
Collaboration aims to evaluate universal genetic testing of breast cancer patients.
IBM, Pfizer Collaborate
Collaboration aims to utilize its drug discovery technology to help accelerate research in immuno-oncology.
Developing a Next-Generation Forensic DNA Analysis Platform
Software to advance Department of Defense forensic capabilities with support for latest DNA technologies.
Agilent, Transcriptic Collaborate
Collaboration aims to automate discovery biology.
CGI, BeiGene Collaborate
Collaboration aims to provide target identification and biomarker discovery services to cancer drug developer BeiGene.
Sanofi, JHL Biotech Announces Strategic Alliance
Alliance to develop and commercialize biologics in China.
AbbVie, Northwestern University Collaborate
Collaboration aims to facilitate and accelerate the development of innovative new therapies against a wide variety of different cancers.
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Events
11th Annual Cold Chain Distrib
12 Dec 2016
11th Annual Cold Chain Distrib ...
New Product Planning Summit
12 Dec 2016
New Product Planning Summit ...
Peptide Drug Design and Delive
13 Dec 2016
Peptide Drug Design and Delive ...
Stability Testing
12 Dec 2016
Stability Testing ...

ePosters
Functional Analysis of RAD51B and RAD23B SNPs using Circular Chromosome Conformation Capture (4C) in Human Prostate Cell Lines
[sup}1.[/sup} The Institute of Cancer Research, 123 Old Brompton Road, London, UK 2.The Royal Marsden NHS Foundation Trust, Fulham Road, London, UK

The aim of this study is to understand the mechanism behind the association between single nucleotide polymorphisms (SNPs), lying in non-coding regions near or within RAD51B and RAD23B, and prostate cancer risk by analysing their interactions with the whole genome using Circular Chromosome Conformation Capture (4C).
Optimization of a Vacuum Ultraviolet Photoionization source for Gas Chromatography used with a High Resolution Time of Flight Mass Spectrometer
LECO Corporation

-Tune solution allows optimization of ion source parameters for
both proton transfer and direct ionization
-Independent ionization processes exist for M+ and MH+
-Optimizing for dopant signal intensity yields inferior results
-Degree of fragmentation remains relatively constant over a
range of source conditions
Preparation of Photonic Biosensors by Inkjet Printing Technology
a AIT Austrian Institute of Technology GmbH, Health & Environment Department, Molecular Diagnostics, Vienna, Austria b ams AG, Unterpremstätten, Austria c University o

In order to enable local functionalization of label-free optical waveguide biosensors in a cost effective mass-fabrication compatible manner, we investigate surface modification employing inkjet printing of functional polymers and UV-curable benzophenone dextran.
Building and deploying digital pathology infrastructure for a heterogeneous user base
Faculty of Medicine, Vrije Universiteit Brussel; University Hospital Brussels (UZ Brussel):

Too often, image analysis and data/image mining projects remain stuck in
microenvironments because they are limited by vendorspecific
solutions that neither scale nor interact with material from other departments or institutions. Successful rollout of digital histopathology therefore requires more than a whole slide scanner. At Brussels Free
University (VUB), we wanted to provide a core digital pathology infrastructure that can support a range of different use cases.
Workshop report: Bioinformatics meets digital pathology
Vrije Universiteit Brussel (Belgium), UMC Radboud (Netherlands), HistoGeneX (Belgium), Rigshospitalet Copenhagen (Denmark), New York College of Podiatric Medicine (USA), Harvard Medical School & Massa

Pathologists are the guardians of large quantities of high-resolution
imaging material, that is barely noticed by bioinformatics today. Yet this (annotated) material can be of huge contributing value to any research project, as pathology preserves topological tissue features, and can help explain difficult phenomena such as tumor heterogeneity. The goal is then to bridge research methods and materials from the bioinformatics community with the (digital) pathology community.
A Novel Cell-Free DNA Extraction System for Cancer Diagnostics
Vela Diagnostics Pte. Ltd., Singapore

We developed a magnetic bead-based cfDNA extraction kit and integrated it into the automated qPCR- and NGS-based IVD workflows. In this study we are compering this magnetic beads-based cfDNA extraction system with a column-based method.
Microfluidic extrusion of cell-laden hydrogel fibers for 3D-Bioprinting
CLNS - iit@Sapienza - Viale Regina Elena 291 - 00161 - Roma

An overview on how the incorporation of microfluidic platforms in 3D-bioprinters can open new routes in the creation of heterogeneous, tissue-specific bio-constructs and in the high-throughput screening of bioinks compositions for regenerative medicine and in vitro tissue modeling.
CRISPR-Cas9 genome editing utilizing chemically synthesized RNA
GE Healthcare Dharmacon, Inc.

Chemical synthesis has been easily applied for rapidly generating either crRNA and tracrRNA or synthetic sgRNA for direct delivery into cells for gene editing applications such as DNA-free options and high throughput arrayed screening.
Analysis of Organic Marker Compounds and Hazardous Organic Compounds by GC/MS to Identify Contamination, Counterfeiting and Adulteration of Spices
SPEX CertiPrep

Our previous study of spices was designed to evaluate the metal content in the spices for evidence of contamination by heavy metals or for adulteration and counterfeiting by notable concentrations of wear or additive metals. This study targeted the same spice samples to quantify the characteristic primary and secondary market compounds for each spice group.
The Chemical Synthesis of Long and Highly Modified RNA using 2'-ACE Chemistry
GE Healthcare Dharmacon, Inc.

Dharmacon has previously developed a novel RNA synthesis chemistry making RNA synthesis as reliable, accessible and of comparable quality as routinely observed in DNA synthesis.
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Application Notes
Adeno-Associated Virus Titer and Aggregation Characterization
Malvern Instruments Limited

In this application note, we describe a novel method to rapidly measure the size and concentration of Adeno-Associated Virus (AAV).
Investigating the Effects of Excipients on the Earliest Stages of Aggregation - Aggregation Inhibition by Arginine
Malvern Instruments Limited

Use of static and dynamic light scattering to characterize the stability of lysozyme in the presence and absence of arginine. SLS is used to assess aggregation temperature, while DLS is used to measure the various particle sizes present in the two formulations at different temperatures, and measurements of zeta potential are used to assess the effect of arginine on the charge state of the protein.
Using DSC to Characterize Thermotropic Phase Transitions in Lipid Bilayer Membranes
Malvern Instruments Limited

The basics of liposome sample preparation and DSC studies.
Monitoring Microfiltration Processes for Water Treatment
Malvern Instruments Limited

Quantifying nanoparticle concentration and size to optimize filtration processes.
Particle Size Analysis of Calcium Carbonates by Laser Diffraction
Malvern Instruments Limited

Calcium Carbonate is used within a wide range of industrial products as a filler and pigment. It is also used as a source of calcium within food and pharmaceutical products. Its function is often related to its particle size and size distribution.
Integrating Automation and DOE to Streamline and Accelerate Quality by Design Activities for Process Chemistry
Unchained Labs

Unchained Labs' tools translate complex experiments into executable methods.
Optimization of a Multi-Mode Detection Model for Measuring Real-time Cellular Respiration and Mitochondrial Function using Fluorophoric Biosensors
BioTek Instruments, Inc.

Cellular metabolism characterization is being aided by the development of new tools designed to provide ease-of-use, higher throughput, and multiplexed data markers for analysis.
Monitoring Saccharomyces Cerevisiea Growth with Bright Field Microscopy in Real Time
BioTek Instruments, Inc.

Strains of the yeast Saccharomyces cerevisiea serve critical roles in the production of many different products including food staples, medicines, and biofuels. The ability to obtain the desired product reliably and repeatedly requires careful monitoring of not only the input materials, but the growth of the yeast strain during the process.
Protein Storage and Stability Analysis Using the Zetasizer Nano ZSP
Malvern Instruments Limited

Spidroins are large, structural proteins that make up the bulk of spider silk fibres. This application note describes the use of a Zetasizer Nano ZSP to characterize their stability at different temperatures.
Preformulation and Stability Studies of Biotherapeutics Using DSC
Malvern Instruments Limited

The Malvern MicroCal VP-Capillary DSC has been used for rapid screening of buffers in preformulation development and for the optimization of storage conditions of antibodies during process development. The results correspond well with those obtained by other more time-consuming methods.
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