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Webcasts
Modifying Cell Lines for Target Discovery and ValidationModifying Cell Lines for Target Discovery and Validation
In this 30-minute seminar, we will discuss the process of genome editing, address factors affecting the design of a genome editing project, and explore the application of modified cell lines for target discovery and validation.
Accelerate Your Research With Tecan´s New Multimode Microplate Reader Platform!Accelerate Your Research With Tecan´s New Multimode Microplate Reader Platform!
In this webinar, solutions will be presented for fast DNA quantification, single cell counting and viability analysis, and automating long-term live kinetic cell assays.

Market Reports
Immunoassay Auto Trends 2014
HTStec

This report comprehensively documents current practices and preferences in immunoassays and to understand future user requirements, particularly with respect to immunoassay automation.
Cell-Based Label-Free Detection Trends 2014
HTStec Limited

This market report summarizes the results of HTStec’s 4th global web-based benchmarking survey on cell-based label-free (LF) detection carried out in July and August 2014. The study also examined in detail the current market landscape, application areas and interest in purchasing new products/systems.
HTS Metrics & Future Direction Trends 2014
HTStec

This market report summarizes the results of HTStec’s global web-based benchmarking survey on high throughput screening (HTS) metrics and future directions carried out in July 2014. The survey was initiated by HTStec as part of its tracking of life science marketplaces and to update our previous report (April 2012). It followed an approach from Pharma to benchmark recent HTS metrics.
Label-Free Binding Analysis Trends 2014
HTStec

This market report summarizes the results of HTStec’s 4th global web-based benchmarking survey on label-free (LF) binding analysis carried out in July 2014. The study was initiated by HTStec as part of its regular (every 2 years) tracking of this life science marketplace. The questionnaire was compiled to address the needs and interests of the LF binding analysis vendor community.
Gene Expression Analysis Market by Technology, Consumables, Services & Applications - Global Forecast to 2018
MarketsandMarkets

Over the years, the gene expression analysis market, comprising of instruments, consumables, and services, has witnessed various technological advancements. These advancements have led to a growth in the number of gene expression applications.
Analytical Instrument Market in the US 2014-2018
Infinity Research

TechNavio's report focuses on the US and has been prepared based on an in-depth market analysis with inputs from industry experts.
Epigenetic Modification Screening Trends 2014
HTStec

This market report summarizes the results of HTStec’s 3nd industry-wide global web-based benchmarking survey on epigenetic modification screening carried out in May 2014.
High Throughput Screening (HTS) Market by Technology, Applications, and End Users - Forecast to 2018
MarketsandMarkets

Technological advancements and flourishing outsourcing industry likely to propel the growth of the global high throughput screening market. In this report, the global high throughput screening market has been segmented on the basis of technology, products, applications, end users, and geography.
Chromatography Resin Market by Application, Techniques & Type - Trends & Forecast to 2018
MarketsandMarkets

The chromatography resin market is expected to grow at a decent pace during the coming decade driven by its increasing application in monoclonal antibody production and food analytics.
Chromatography Accessories and Consumables Market by Types, Technology & End-users - Trends & Global Forecasts to 2018
MarketsandMarkets

The chromatography accessories and consumables market demands significant investments in R&D in order to constantly come up with new and innovative products and technologies.
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Scientific News
In vivo CRISPR-Cas9 Screen Sheds Light On Cancer Metastasis And Tumor Evolution
Genome-scale study points to drivers of tumor evolution and metastasis, provides roadmap for future in vivo Cas9 screens.
Medical Nanoparticles: Local Treatment Of Lung Cancer
Working in a joint project at the NIM Excellence Cluster, scientists from the Helmholtz Zentrum München and the Ludwig-Maximilians-Universität in Munich have developed nanocarriers that site-selectively release medicines/drugs at the tumor site in human and mouse lungs.
New Detector Sniffs Out Origins Of Methane
Instrument identifies methane’s origins in mines, deep-sea vents, and cows.
URI Researchers Invent Lab-On-Paper
New paper-based platform for conducting a wide range of complex medical diagnostics.
TSRI Scientists Find Clues to Cancer Drug Failure
A pair of studies show how the primary protein responsible for multidrug chemotherapy resistance changes shape.
MR Spectroscopy Shows Precancerous Breast Changes in Women with BRCA Gene
A technique that monitors biochemical changes in tissue could improve the management of women at risk of breast cancer.
Adults Only Really Catch Flu About Twice a Decade, Suggests Study
Researchers developed a mathematical model of how our immunity to flu changes over a lifetime as we encounter different strains of the virus.
Water In Smog May Reveal Pollution Sources
Vapor variations in SLC inversions tied to cars, furnaces.
New Nanodevice Defeats Drug Resistance
Tiny particles embedded in gel can turn off drug-resistance genes, then release cancer drugs.
Genetically Speaking, Mammals Are More Like Their Fathers
A first of its kind study shows that who we inherit genetic variants from – our mother or father – is crucial for the development of diseases and for research studies aimed at finding causes and potential treatments.
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Business News
Arrowhead Acquires Novartis' RNAi R&D Portfolio
The acquisition includes multiple patent families covering RNAi-trigger design rules and modifications.
SYGNIS Signs Initial Distribution Agreement with FUNAKOSHI
TruePrime™ family for whole genome amplification without the need of synthetic random primers on stock and ready for distribution in Japan.
ChemInteract Consortium Wins Funding to Develop Chemical Toxicity Assessment Tool
New technology aims to reduce animal testing and improve safety testing of chemicals.
SCIEX and Labor Berlin Collaboration to Advance Forensic Testing
Collaboration for the development of a hybrid Quadrupole Time-of-Flight (TOF) MS/MS reference library.
The Role of NGS in Stratified Cancer Medicine
Clinical Scientists reveal the promise and considerations for next generation sequencing in stratified cancer medicine.
Consistent Scalable Functionalised Graphene Capacity
Haydale has annoynced further significant investment in production capacity.
TGAC Receives Advanced NGS Training
TGAC hosted PerkinElmer’s training session, “Advanced Automated NGS Library Preparation” with participants from across Europe to gain hands-on experience in protocols for PerkinElmer’s robot technologies.
Fidelta Achieves Milestone in Collaboration with LEO Pharma
Next phase of the project will contribute significantly to Fidelta's revenues in 2015.
Genedata Biologics Licensed by Pfizer
Pfizer implements Genedata Biologics to streamline global biopharma R&D processes.
Adaptimmune Strengthens Management Team with Key Executive Hires
Adaptimmune has strengthened its senior management team with the appointment of Dr. Rafael Amado, as Chief Medical Officer, and Adrian (Ad) Rawcliffe, as Chief Financial Officer.
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Events
8th Lean, Six Sigma, Kaizen an
09 Mar 2015
8th Lean, Six Sigma, Kaizen an ...
Clinical Trial Supply New Engl
10 Mar 2015
Clinical Trial Supply New Engl ...
Pittcon 2015
08 Mar 2015
Pittcon 2015 ...
49th Annual WAI Conference
11 Mar 2015
49th Annual WAI Conference ...

ePosters
Cell-Mediated Cytotoxicity Assay by High-Throughput Direct Cell Counting in Microplates using Fluorescence-Based Image Cytometry
Nexcelom Bioscience LLC,The University of Texas MD Anderson Cancer Center.

In this work, we demonstrate a novel high throughput cytotoxicity detection assay using the Celigo Imaging Cytometry method. Utilizing imaging cytometry, direct cell counting of live fluorescent target cells can be performed, which is a direct method for assessment of cytotoxicity.
Droplet-on-Demand Platform for Biochemical Screening & Drug Discovery
[1] University of Cambridge, UK [2] The Dolomite Center, 27 Jarman Way, Royston, SG8 5HW, UK [3] ETH Zürich, SWITZERLAND [4] Imperial College London, UK [5] University of Southampton, UK

To demonstrate droplet on demand applications towards study of biological entities encapsulated in nanoliter droplets. Interfacing a droplet on demand platform with microfluidic chips allows for merging and dilution of droplets. This feature is applied to encapsulate yeast cells (S. cerevisiae) and multicellular organisms (C. elegans).
Long-term on-chip storage and release of liquid reagents for diagnostic lab-on-a-chip applications
*Robert-Bosch-GmbH - Robert-Bosch-Platz 1, 70839 Gerlingen-Schillerhöhe, Germany. **University of Freiburg, Department of Microsystems Engineering - IMTEK, 79110 Freiburg, Germany

We present a concept which enables on-chip storage of liquid reagents at room temperature and allows an easy implementation into pressure driven LoC devices.
Direct Targets Identification of a Bioactive Compound
Charnwood Molecular, Hybrigenics services SAS

Identifying protein partners of a small bioactive molecule is of great
interest in many aspects of life sciences and specifically in the drug
discovery and development process cycle. It is a support to (i) decipher
the mechanism of action after for example a “High Content” screening,
(ii) study “off-target” effects, (iii) adjust therapeutic indications and
clinical regimens of a drug and (iv) consider drug repositioning.
3D-Tissue/ Whole-blood Co-culture Models Combined with Multi-Analyte Profile (MAP) Analyses for In-vivo-like Immunopharmacology
HOT Screen GmbH, Reutlingen (Germany)

Human Organotypic Test (HOT) Systems aim at in-vivo like substance characterisation of all preparations meant to act on the human immune system.
A multiplexed amplicon sequencing technology for FFPE and circulating, cell-free DNA
Swift Biosceinces

A novel amplicon approach allowing for hundreds of amplicons to be multiplexed in a single tube with a two workflow from sample to sequencer.
Response to ragweed allergen provocation in the Red Maple Trials Allergen Challenge TheatreTM


Response to ragweed allergen provocation in the Red Maple Trials Allergen Challenge Theatre
Field Performance of a New Technology with the Potential to Identify Allergy and Asthma Triggers
Inspirotec LLC, Glenview, IL, Argonne National Laboratory, Lemont, IL, Department of Ecology and Evolution, University of Chicago, Chicago, IL

This work introduces a very simple plug-and-play device that can sample air at a high volume flow rate with no moving parts. Aerosol particles are captured on electrodes and eluted for testing. We show that performance of the device is substantially equivalent to capture by pumping through a filter for immunological and molecular analysis.
Phenotypic Screening Applied to the Anti-biofilm Drug Discovery: Identification of Anti-biofilm Flavonoids from a Chemical Library
1Pharmaceutical Sciences, Department of Biosciences, Åbo Akademi University, Finland 2Division of Pharmaceutical Biosciences, Faculty of Pharmacy, University of Helsinki, Finland

This work represents a systematic exploration of a flavonoids collection for the inhibitory activity against Staphylococcus aureus biofilms and offers an improved methodological workflow for anti-biofilm screens of chemical libraries taking into account the connections between anti-biofilm and antibacterial properties.
An investigation into the effects of aging on automotive bumper samples by xylene soluble flow injection polymer analysis (XS-FIPA)
Malvern Instruments Ltd

This poster describes the use of flow injection polymer analysis (FIPA) as an analytical tool for xylene soluble (XS) determination with quick and easy simultaneous measurements of molecular weight (MW), intrinsic viscosity (IV) and XS%. The technique was applied to automotive bumper samples which had undergone an aging test. The results from the XS-FIPA technique highlight the differences caused by the aging process.
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Application Notes
Capturing Single Cells in Droplets using Density Media
Dolomite

Encapsulation of single cells is facilitated by the use of density matching media.
Droplet on Demand Generation and Pairwise Merging
Dolomite

This application note demonstrates the ability of the Mitos Dropix® Droplet Merging System to reproducibly generate and subsequently merge droplets from tens to hundreds of nanolitres with a wide range of volume ratios.
Water in Mineral Oil in Water (W-O-W) Double Emulsion Production using SDS, PGPR and Tween® 80 as Emulsifiers
Dolomite

This application note reports on the production of monodisperse double emulsion droplets produced in a single step using a microfluidic approach.
Colorimetric Estimation of Protein Content in Gelatin Microparticles
Dolomite

This application note demonstrates a colorimetric method to quantify protein content inside micrometer sized gelatin hydrogel particles.
Introduction to Mixing and Droplet Production in Microfluidics
Dolomite

This application note introduces researchers to fundamental fluid operations in microfluidics.
CHO Cell Encapsulation & Incubation in Gelatin Particles
Dolomite

Cell encapsulation in picoliter volume droplets is demonstrated in this application note using Dolomite’s Droplet system.
Agarose Bead Synthesis - A Microfluidic Route for the Production of Micron Sized Agarose Hydrogel Beads
Dolomite

This application note describes the generation of agarose droplets at elevated temperature and subsequent cooling to form solid microparticles.
Droplet on Demand Generation & Droplet Splitting
Dolomite

This application note demonstrates the Mitos Dropix® Splitting System to reproducibly generate nanoliter volume droplets, and subsequently split them into picoliter droplets of varying volumes.
Understanding the Effect of Molecular Weight and Structure on the Performance Characteristics of Cellulose Derivatives using OMNISEC
Malvern Instruments Limited

This application note describes the analyses of a variety of aqueous (water-soluble) cellulose derivatives using the OMNISEC triple detection system and the subtle, yet distinct differences between these different derivatives that can be parsed out by the OMNISEC system.
Forensic Analysis of an Artificial Sweetener Commonly Employed in Hoax Powder Attacks using Morphologically Directed Raman Spectroscopy
Malvern Instruments Limited

This application note details how Morphologically Directed Raman Spectroscopy (MDRS) using the Morphologi G3-ID can be applied to the forensic identification of commercially sourced white powders commonly used in hoax powder attacks.
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