New Software Spots, Isolates Cyber-attacks to Protect Networked Control Systems
Software algorithm detects and isolates cyber-attacks on networked control systems that are becoming increasingly important to national infrastructure

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Computational Tool Translates Complex Data into 2-Dimensional Images
May allow doctors to track progression of cancer, response to treatment, and risk of relapse.

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Program for Breakthrough Biomedical Research to Celebrate 15 Years
A program that fosters basic science projects of potentially high impact is celebrating 15 years of discovery at UC San Francisco.

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Environmental Law Institute Recognizes Penn State Wetlands Scientist
Robert P. Brooks, a wetlands scientist at Penn State, has received the 2013 National Wetlands Award for Science Research.

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Scientists Identify Molecular Trigger for Alzheimer’s Disease
New research establishes nature of malfunction in protein molecules that can lead to onset of dementia.

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TATAA Strengthens Quality Assurance Program
TATAA Biocenter expands offerings using AATI’s Fragment Analyzer™ to assess RNA quality in gene expression analysis.

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Non-Wetting Fabric Drains Sweat
Waterproof fabrics that whisk away sweat could be the latest application of microfluidic technology developed by bioengineers.

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miRNA Regulated Networks Identified in Cystic Fibrosis
The IDT newsletter DECODED features the latest research to rescue the CFTR functionality.

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Osteoarthritis Progression Halted in Mice
If successful in humans, joint replacement surgery might be avoidable.

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Finding, Fighting the Fat that Fuels Cancer
UT Southwestern research examines role of certain fat cells in tumorigenesis.

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India Laboratory Information Management System Market Trends 2013
Researchmoz releases report on LIMS market segment status in India

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Personalis Selects Clarity LIMS, Citing Quick Deployment as Driver
Clarity LIMS User Base Growing

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American Engineering Testing Inc. Implements QESTLab, QESTField and Construction Hive
LIMS implementation expected to improve the efficiency and quality of AET operations by electronically registering samples and entering data in the field.

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Bruker and SCiLS GmbH Announce an Exclusive Partnership for SCiLS Lab Software for MALDI Imaging
SCiLS Lab is the software developed by SCiLS GmbH which allows the user-friendly statistical analysis of large MALDI imaging datasets

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Core Informatics and OpenEye Scientific Software Forge Partnership
New partnership includes integration of OpenEye cheminformatics software into Core Informatics’ web-based LIMS and ELN

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UK-Norwegian Collaboration Aims to Develop a New Living Skin Equivalent Model
New in vitro human living skin equivalent model for testing inflammatory responses.

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G-BA Issues Final Assessment Report for PIXUVRI®
Pricing negotiations to begin in June.

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Exco InTouch Joins C-Path ePRO Consortium
Company joins ePRO Consortium to advance electronic data capture in clinical trials.

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AB SCIEX Announces In Vitro Diagnostic Devices CE Marked for Europe
AB SCIEX launches the 3200MD CE-IVDD series for general in vitro diagnostic use in Europe.

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RainDance Attracts Top-Tier Commercial Leadership to Accelerate Global Growth
RainDance Technologies, Inc. has announced several high-profile additions to its commercial leadership team.

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Microfluidic Sample Extraction Device with an Integrated Pressure Measurement
IMTEK, University of Freiburg

Bioanalytical applications, like the monitoring of metabolic processes, often require a continuous sample extraction. In this work we describe a microfluidic device which is able to subsequently extract samples in microliter range out of a continuous sample stream and provides an optional integrated channel for the measurement of the fluid pressure.

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Concentration and Mixing Effects on the Production of Amine Hydrochloride Salts in a Confined Impinging Jet Reactor
University of Alberta

Results show that different AHC salts can be formed under different process conditions.

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Cytosolic Delivery of Anticancer Drug Using Endosomolytic Peptide Bearing Nanoparticles Against Solid Tumor
Dr. Hari Singh Gour University, Sagar

The objective of the present project is to develop transferrin coupled biodegradable nanoparticles (NPs) with high encapsulation efficiency (Doxorubicin). GALA (Glutamic acid-alanine-leucine alanine) a pH sensitive fusogenic endosomolytic peptide is added to the formulation to enhance the endosomal lysis that will further potentiate the delivery of anticancer drug inside tumor cell as well as prevent loss of drug via endosomes.

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Highly Efficient Activated Carbon From Palm Shell as an Adsorbent of Toxin/Poison
International Islamic University Malaysia

Highly efficient activated carbon as an adsorbent of toxins has been successfully produced from palm shell through chemical activation process using phosphoric acid as activating agents.

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Oral Health Management of a Patient with 47 XYY Syndrome
College of Dentistry, Salman bin Abdulaziz University

The 47XYY syndrome is an aneuploidy of sex chromosomes, where a human male receives an extra Y-chromosome making a total of 47 instead of the usual 46.

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The Challenges of Relieving Cancer Pain: A Literature Review
NHS

This study aims to explore the discrepancy between the increasing array of treatments for cancer pain, as well as the evidence that it can be managed effectively in the majority of cases, and its persisting prevalence.

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Colony Forming Cell (CFC) Assays Predict for Increased Clinical Neutrophenia with Combination Therapies
ReachBio LLC

This study aimed to assess if the CFC assay could also be useful at predicting the increased toxicity of drug combinations relative to the toxicity caused by the relevant single agent.

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Predictive in silico Screening to Determine Vector-Mediated Transport Properties for the Blood-Brain Barrier Choline Transporter
University of Wurzburg

An attempt to analyze vector-mediated transport properties for the blood-brain barrier choline transporter (BBBCHT) was made to assess and improve drug delivery to the central nervous system.

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Comparison of Dissociated Phoria Measuring Methods. Repeatability and Reliability
CBO

The aim of this study is to determine the reliability and compare reproducibility of different dissociated phoria measure tests.

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Fast Liquid Differential Scanning Calorimetry (FLDSC)
Xensor Integration

Lysozyme experiments show that protein unfolding can be recorded at scan rates of up to 1000 °C/s, and for lysozyme concentrations of 1 % and probably even down to 0.1%.

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An Integrated Solution to Simplify Library Preparation and Multiplexing for NimbleGen Sequence Capture
Bioo Scientific

The studies described herein demonstrate the capability of Bioo Scientific’s novel NEXTFlex™ DNA Pre-Capture Combo Library construction kits used in conjunction with the NimbleGen Sequence Capture technology to obtain high coverage comparative genomic data from a panel of human HapMap DNA samples.

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Direct Visualisation, Sizing and Counting of Aggregation in Proteins
NanoSight Ltd

Characterising the state of aggregation in proteins is of paramount importance when trying to understand biopharmaceutical product stability and efficacy. Product quality, both in terms of biological activity and immunogenicity can be highly influenced by the state of protein aggregation.

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Direct Visualisation, Sizing & Counting of Viruses and Phages in Liquid Suspension
NanoSight Ltd

A new laser-based nanoparticle tracking analysis system is now available which allows nanoscale particles such as viruses and virus aggregates to be directly and individually visualised in liquids in real-time, from which high-resolution particle size distribution profiles can be obtained.

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ORAC Assay for the Determination of Antioxidant Capacity in Foods
Tecan Group - Products

Measuring oxygen radical absorbance capacity with the Infinite® 200 PRO multimode reader.

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Automated Growth Monitoring of Microaerophilic Organisms
Tecan Group - Products

Walkaway growth monitoring of Helicobacter pylori in the Infinite® 200 PRO reader with Gas Control Module (GCM™).

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Rapid Critical Micelle Concentration (CMC) Determination Using Fluorescence Polarization
BioTek Instruments

The determination of the critical micelle concentration (CMC) value of surfactants under different environmental conditions is important for a number of different biological and chemical processes. Because the CMC is not a constant value, shifting with different environmental conditions, it is important that a rapid, reliable and easy methodology be available to facilitate testing.

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Analysis of a New High Throughput Screening Detection Technology for Rapid hERG Safety Testing using a Fluorescence Polarization Assay
Biotek Instruments

Support Synergy™ Neo launch by providing speed and sensitivity data for Fluorescence Polarization detection mode in low volume 384-well plate using hERG biochemical assay as a Model.

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BRD4 Bromodomain 1 Inhibitor Screening Using a Homogeneous Proximity Assay
BioTek Instruments

Demonstration of profiling and primary screening of an epigenetic target; a histone acetylating bromodomain. This is a TR-FRET based application highlighting the use of automated instrumentation and a high-throughput screening (HTS) multi-mode microplate reader.

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Integration of Liquid Handler Quality Control Into the HTS Daily Routine
Artel

This application note describes how the Artel MVS® Multichannel Verification System can be used to assess the performance of the liquid handlers integrated into a PerkinElmer cell::explorer high throughput screening (HTS) system.

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Purification of Genomic DNA from Saliva Using Oragene® Discover Collection Kits and the Akonni TruTip® Extraction System on the Hamilton Microlab® STAR Liquid Handling Workstation
Hamilton

In the following studies, we have demonstrated the high precision of the automated TruTip extraction technology in processing genomic DNA from low-volume saliva samples and its advantage over competitors.

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