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Thursday, January 29, 2015
 
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Webcasts
Accelerate Your Research With Tecan´s New Multimode Microplate Reader Platform!Accelerate Your Research With Tecan´s New Multimode Microplate Reader Platform!
In this webinar, solutions will be presented for fast DNA quantification, single cell counting and viability analysis, and automating long-term live kinetic cell assays.
Kinases as Targets for Drug Discovery in an Academic SettingKinases as Targets for Drug Discovery in an Academic Setting
William Janzen,The University of North Carolina at Chapel Hill, speaking at Drug Discovery and Development 2014

Market Reports
Immunoassay Auto Trends 2014
HTStec

This report comprehensively documents current practices and preferences in immunoassays and to understand future user requirements, particularly with respect to immunoassay automation.
Cell-Based Label-Free Detection Trends 2014
HTStec Limited

This market report summarizes the results of HTStec’s 4th global web-based benchmarking survey on cell-based label-free (LF) detection carried out in July and August 2014. The study also examined in detail the current market landscape, application areas and interest in purchasing new products/systems.
HTS Metrics & Future Direction Trends 2014
HTStec

This market report summarizes the results of HTStec’s global web-based benchmarking survey on high throughput screening (HTS) metrics and future directions carried out in July 2014. The survey was initiated by HTStec as part of its tracking of life science marketplaces and to update our previous report (April 2012). It followed an approach from Pharma to benchmark recent HTS metrics.
Label-Free Binding Analysis Trends 2014
HTStec

This market report summarizes the results of HTStec’s 4th global web-based benchmarking survey on label-free (LF) binding analysis carried out in July 2014. The study was initiated by HTStec as part of its regular (every 2 years) tracking of this life science marketplace. The questionnaire was compiled to address the needs and interests of the LF binding analysis vendor community.
Gene Expression Analysis Market by Technology, Consumables, Services & Applications - Global Forecast to 2018
MarketsandMarkets

Over the years, the gene expression analysis market, comprising of instruments, consumables, and services, has witnessed various technological advancements. These advancements have led to a growth in the number of gene expression applications.
Analytical Instrument Market in the US 2014-2018
Infinity Research

TechNavio's report focuses on the US and has been prepared based on an in-depth market analysis with inputs from industry experts.
Epigenetic Modification Screening Trends 2014
HTStec

This market report summarizes the results of HTStec’s 3nd industry-wide global web-based benchmarking survey on epigenetic modification screening carried out in May 2014.
High Throughput Screening (HTS) Market by Technology, Applications, and End Users - Forecast to 2018
MarketsandMarkets

Technological advancements and flourishing outsourcing industry likely to propel the growth of the global high throughput screening market. In this report, the global high throughput screening market has been segmented on the basis of technology, products, applications, end users, and geography.
Chromatography Resin Market by Application, Techniques & Type - Trends & Forecast to 2018
MarketsandMarkets

The chromatography resin market is expected to grow at a decent pace during the coming decade driven by its increasing application in monoclonal antibody production and food analytics.
Chromatography Accessories and Consumables Market by Types, Technology & End-users - Trends & Global Forecasts to 2018
MarketsandMarkets

The chromatography accessories and consumables market demands significant investments in R&D in order to constantly come up with new and innovative products and technologies.
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Scientific News
“Unprecedented Sensitivity and Specificity” in Ovarian Cancer
Study of the use of the Parsortix system as a clinical application in the detection and treatment of ovarian cancer patients.
Nanoparticle Lights Up Artery-Clogging Plaque
A new imaging agent that may light up dangerous plaque in arteries is to be evaluated in a clinical trial.
Study Uncovers Range of Molecular Alterations in Head and Neck Cancers
TCGA tumor genome sequencing analyses offer new insights into the effects of HPV and smoking, and find genomic similarities with other cancers.
Beating The Clock: New Treatment For Rabies Developed
University of Georgia researchers have developed a new treatment for rabies.
New Cells May Help Treat Diabetes
UI group creates insulin-producing cells that normalize blood-sugar levels in diabetic mice.
NIH Launches Tool to Advance Down Syndrome Research
Web portal will help approved professionals to plan clinical studies.
Cancer-Causing Virus Blocks Human Immune Response
Epstein-Barr virus shown to outwit the human immune response using microRNAs.
Telomere Extension Turns Back Aging Clock In Cultured Cells
Researchers delivered a modified RNA that encodes a telomere-extending protein to cultured human cells. Cell proliferation capacity was dramatically increased, yielding large numbers of cells for study.
Role of Immune System in Promoting Digestive Health
Study shows that the immune system helps to promotes digestive health by fostering community of “good” gut bacteria.
Nanodiamonds Deliver Cancer Drug To Kill Chemoresistant Cancer Stem Cells More Effectively
Delivery of Epirubicin by nanodiamonds resulted in a normally lethal dosage of Epirubicin becoming a safe and effective dosage for treatment of liver cancer.
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Business News
Wyss Institute Videos Now on LabTube
The Wyss Institute for Biologically Inspired Engineering has created a channel on Labtube.
Quest Diagnostics and CDC Expand Public Health Collaboration
Multi-year fee-based contract for Quest's test data and analytics expertise aims to reveal insights from national testing trends to promote guideline-based care and better outcomes for 4.4 million Americans with viral hepatitis.
Actavis to Acquire Auden Mckenzie for 306M GBP
Immediately accretive to Non-GAAP earnings.
SGS Announces Expansion at its West Chester, PA
Facility to increase protein structural analysis services.
PDA Launches Manufacturing Science ProgramSM
2015 PDA Annual Meeting includes a track dedicated to manufacturing performance.
Dalton Pharma Services Expands Sterile Powder Manufacturing Capabilities
Addition of a high-speed automated sterile powder filling line.
ASI to Manufacture Amotosalen Active Pharmaceutical Ingredient
U.S Food and Drug Administration approves ASI's manufacturing facility in Riverview, Michigan.
Otsuka Australia Pharmaceutical Pty Ltd Opens in Australia
Company opens its first office in Australia, furthering the company’s aim of bringing innovative new treatments to patients in Oceania.
Recipharm Ready for Serialization and Delivers Complex Project for China
Already supplied fifty seven (57) serialized batches.
Horizon Discovery CEO Darrin Disley wins Entrepreneur of the Year
Darrin Disley, CEO of Horizon Discovery, wins Entrepreneur of the Year award at the Quoted Company Awards 2015.
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Events
5th Annual Pharmacovigilance a
29 Jan 2015
5th Annual Pharmacovigilance a ...
Novel Immunotherapeutics Summi
29 Jan 2015
Novel Immunotherapeutics Summi ...
13th Cytokines & Inflammation 
29 Jan 2015
13th Cytokines & Inflammation  ...
7th Immunotherapeutics & Immun
29 Jan 2015
7th Immunotherapeutics & Immun ...

ePosters
IDENTIFICATION AND DIFERENTIATION OF Verticillium SPECIES WITH PCR MARKERS AND SEQUENCING OF ITS REGION


The genus Verticillium is a group of ascomycete fungi, including plant-pathogenic species capable of affecting the vasculature of many agricultural crops, and therefore causes major economic losses worldwide. In 2011, a new taxonomic classification of the genus was proposed, which is now referred to as Verticillium sensu stricto, comprising ten species: V. dahliae V. albo-atru, V. alfalfae, V. longisporum, V. nonalfalfae, V. tricorpus, V. zaregamsianum, V. nubilum, V. isaacii and V. klebahnii. <
Automated detection and control of controlled substances
Scitegrity Limited

Scitegrity, in conjunction with the Pistoia Alliance and a number of pharmaceutical companies, have developed Controlled Substances Squared to scan large chemical libraries (millions of compounds) and determine whether a compound is considered as controlled in a selected country.
Apoplastic Venom Allergen‐like Proteins of Cyst Nematodes Modulate the Activation of Basal Plant Innate Immunity by Cell Surface Receptors
aLaboratory of Nematology Wageningen University, 6708 PB, Wageningen, The Netherlands; bCentre for BioSystems Genomics, 6700 AB, Wageningen, The Netherlands

We conclude that parasitic nematodes most likely utilize VAPs to suppress the activation of defenses by immunogenic breakdown products in damaged host tissue.
A pico-liter semi-automated screening method for morphological identification of microorganisms from environmental samples
Department of Microbiology, Ramnarain Ruia College, Mumbai,India

An economically feasible microfabrication protocol was developed for fabricating micro features used for bacterial analysis from environmental samples like soil and green sulfur bacteria sample. Organisms were classified in 11 morphotypes by using open source Image analysis software named CMEIAS and the standardized protocol was confirmed by viable count and pure culture study


Busted! First Dection of Steroid Hormones in Pacific Walrus Bones
University of Alaska Fairbanks School of Fisheries and Ocean Sciences, Museum of the North, and National Science Foundation

The Pacific walrus (Odobenus rosmarus divergens) is a candidate species for the Endangered Species List because Arctic sea ice has declined significantly in the past decades. This project focuses on validating a method for extracting steroid hormones from archaeological, historical, and modern bone creating a baseline of hormone levels during different climate regimes. The results validate our method of hormone extraction as all steroid hormones were extracted from bones of all time frames.
Population characterization of Brazilian isolates of Ceratocystis spp. using microsatellites
1Faculdade de ciências agronômicas, UNESP Botucatu, SP. Brazil   2Forestry and Agricultural Biotechnology Institute (FABI), Private Bag X20, University of Pretoria, Pretoria, 0028, South Africa

The genus Ceratocystis includes several species of economically important plant pathogens and has a global distribution. In Brazil, species in the genus cause disease and death of hosts such as cacao, eucalypts and mango. This study aimed to characterize the population structure and diversity of isolates of Ceratocystis fimbriata sensu lato collected from diseased Eucalyptus species and to compare these to isolates from cacao, mango, teak, fig, rubber and atemoya.
Geneious R8: A Powerful and Comprehensive Suite of Molecular Biology Tools

Biomatters, Inc & Biomatters, Ltd.

Geneious R8: A powerful and comprehensive suite of molecular biology tools.
Putative Genes Identified on Two Growth Conditions of G. boninense


Putative genes identified on two growth conditions of Ganoderma boninense.
Identifying marker-trait associations for Fiber Components in Sugarcane with Simple Sequence Repeat Markers
1 Institute of Biosciences, Department of Genetics , University of São Paulo state “Júlio de Mesquita Filho”, Brazil; 2 CTC- Center of Sugarcane Technology, Brazil; 3 Texas A&M Agrilife Research,

Identifying marker-trait associations for Fiber Components in Sugarcane with Simple Sequence Repeat Markers.

Ichthyophonus vs. Proteins: Should we be eating these fish?
Polaris K-12 School, Alaska Pacific University Fisheries and Aquatic Science and Technology Laboratory(FAST Lab)

The project, Ichthyophonus vs. Proteins, analyzes the effect of Ichthyophonus on the protein content of Halibut from Homer. This experiment found that Ichthyophonus does not have a significant effect on the protein content of the tested Halibut. The findings confirm the belief that Ichthyophonus is not harmful to humans and the Halibut are still safe to eat.
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Application Notes
Directional qRNA-Seq: Combining the Power of Stranded RNA-Seq with the Quantitative Precision of Molecular Labels
Bioo Scientific

Bioo Scientific introduces a novel product for advanced RNA-Seq library preparation that features strand-specific RNA sequencing and correction of PCR amplification bias by molecular indexing: the NEXTflex™ Rapid Directional qRNA-Seq™ Kit.
Pharmaceutical Excipient Characterization
Malvern Instruments Limited


Quantifying shear thinning behavior on a rotational rheometer using the power law model
Malvern Instruments Limited

This application note shows how the power law model can be used to quantify shear thinning behavior and for comparing between products and formulations.
Quantifying viscosity recovery following extrusion or spraying using thixotropy assessment on a rotational rheometer
Malvern Instruments Limited

This app note shows how a three step shear rate test can be used to evaluate the extent of viscosity recovery following extrusion from a tube or bottle.
Interfacing Viscotek detectors with Waters SEC systems and Waters Empower® software
Malvern Instruments Limited

This technical note describes how to connect Viscotek detectors to Waters systems, in particular the Waters Alliance® system, and how to use OmniSEC in combination with Empower® to run trouble-free separation sequences.
Measuring protein molecular weight using the Viscotek SEC-MALS 20 connected to a Waters Empower® SEC system
Malvern Instruments Limited

In this application note, we show that Malvern’s OmniSEC software can now communicate with Waters Empower® for the seamless exchange of sample sequences. A selection of proteins was used to demonstrate the measurement of protein molecular weight, oligomeric and aggregation state.
Measuring Exosome Stability with Nanoparticle Tracking Analysis
Malvern Instruments Limited

Here, an LM10 is used to measure the size and concentration of exosomes after storage at two different temperatures, 4°C and room temperature.
Approaching Single-Cell Sequencing by Understanding NGS Library Complexity and Bias
Swift Biosciences Inc

This application note describes the sequence coverage performance andp reservation of molecular complexity of next generation sequencing (NGS) libraries generated from human and microbial genomic DNA using the Accel-NGS™ 2S DNA Library Kit for whole-genome sequencing (WGS) on the Illumina® platform.
Accelerating the Development of Optimized Therapeutic Protein Formulations using Differential Scanning Calorimetry
Malvern Instruments Limited

DSC data is useful in predicting the stability of a protein in solution. The Tm indicates thermostability, and Tm determination in different formulations is an approximate measure of the susceptibility to aggregation and other irreversible changes at lower temperatures.
Assessing Drug Encapsulation Efficiency using Nanoparticle Tracking Analysis
Malvern Instruments Limited

In this application note we describe the use of Nanoparticle Tracking Analysis (NTA) for size and concentration measurements of drug delivery nanoparticles. In addition, by using a fluorescently tagged drug molecule, it was possible to determine how many drug delivery nanoparticles had successfully been loaded with drug molecules.
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