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Webcasts
Free up your time - Easy automation of your routine liquid handling tasksFree up your time - Easy automation of your routine liquid handling tasks
In this webinar we will discuss routine liquid handling tasks and illustrate how fast and effortless they can be transferred to our liquid handling workstation.
A Streamlined Approach for Biotherapeutic CharacterizationA Streamlined Approach for Biotherapeutic Characterization
This presentation will discuss a streamlined solution for collecting and processing data for routine intact mass and peptide workflows.

Market Reports
High Throughput Assay Trends 2015
HTStec Limited

This market report summarizes the results of HTStec’s industry-wide global web-based benchmarking survey on high throughput flow cytometry (HT flow) screening carried out in December 2014.
Mobile Technology In The Lab Trends 2015
HTStec Limited

This market report summarizes the results of HTStec’s industry-wide global web-based benchmarking survey on the use of mobile technology to monitor and control of lab instruments and automated systems carried out in April 2015.
Epigenetic Proteins & Reagents Trends 2015
HTStec Limited

This market report summarizes the results of HTStec’s industry-wide global web-based benchmarking survey on epigenetic proteins and reagents carried out in March 2015.
3D Spheroid Culture Trends 2015
HTStec Limited

This market report summarizes the results of HTStec’s industry-wide global web-based benchmarking survey on three dimensional (3D) spheroid culture carried out in May 2015.
Immunoassay Auto Trends 2014
HTStec

This report comprehensively documents current practices and preferences in immunoassays and to understand future user requirements, particularly with respect to immunoassay automation.
Cell-Based Label-Free Detection Trends 2014
HTStec Limited

This market report summarizes the results of HTStec’s 4th global web-based benchmarking survey on cell-based label-free (LF) detection carried out in July and August 2014. The study also examined in detail the current market landscape, application areas and interest in purchasing new products/systems.
HTS Metrics & Future Direction Trends 2014
HTStec

This market report summarizes the results of HTStec’s global web-based benchmarking survey on high throughput screening (HTS) metrics and future directions carried out in July 2014. The survey was initiated by HTStec as part of its tracking of life science marketplaces and to update our previous report (April 2012). It followed an approach from Pharma to benchmark recent HTS metrics.
Label-Free Binding Analysis Trends 2014
HTStec

This market report summarizes the results of HTStec’s 4th global web-based benchmarking survey on label-free (LF) binding analysis carried out in July 2014. The study was initiated by HTStec as part of its regular (every 2 years) tracking of this life science marketplace. The questionnaire was compiled to address the needs and interests of the LF binding analysis vendor community.
Epigenetic Modification Screening Trends 2014
HTStec

This market report summarizes the results of HTStec’s 3nd industry-wide global web-based benchmarking survey on epigenetic modification screening carried out in May 2014.
Multi-Channel Pipettor QC Trends 2014
HTStec

Multi-channel pipettors are essential tools in most life science laboratories today. Yet the impact of undertaking quality control (QC) measures on improving data quality, enhancing productivity/efficiency and reducing experimental failures has only relatively recently been recognized. Understanding how lab users approach the issue of pipettor QC is important as the industry struggles to adopt standards for automated pipetting.
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Scientific News
Featured Article
Point of Care Diagnostics - A Cautious Revolution
Advances in molecular biology, coupled with the miniaturization and improved sensitivity of assays and devices in general, have enabled a new wave of point-of-care (POC) or “bedside” diagnostics.

Featured Article
Mass Spec Technology Drives Innovation Across the Biopharma Workflow
With greater resolving power, analytical speed, and accuracy, new mass spectrometry technology and techniques are infiltrating the biopharmaceuticals workflow.

Featured Article
One Step Closer to Precision Medicine for Chronic Lung Disease Sufferers
A study led by University of North Carolina at Chapel Hill, and National Jewish Health, has provided evidence of links between SNPs and known COPD blood protein biomarkers.

Blood Pressure Drug May Boost Effectiveness of Lung Cancer Treatment
Researchers at Imperial College London have suggested that the blood pressure drug may make a type of lung cancer treatment more effective.
Insight into Eye Diseases
Scientists recreate zebrafish cell regeneration from retinal stem cells in mice.
New Discovery May Benefit Farmers Worldwide
Scientists have shown how a crop-microbe 'team' protect against fungal infection.
Antibodies Paving the Way to HIV Vaccine
Researchers uncover factors responsible for the formation of broadly neutralizing HIV antibodies in humans.
Designing Drugs with a Whole New Toolbox
Researchers develop methods to design small, targeted proteins with shapes not found in nature.
Protein Studies Discover Molecular Secrets
Two protein studies have mapped proteins that reveal the secrets to recycling carbon and healing cells.
Tapping Evolution to Improve Biotech Products
Researchers show how 'ancestral sequence reconstruction' can be used to guide engineering of a blood clotting protein.
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Business News
Quotient Clinical Expands Data Sciences Capability
The expansion comes in response to growing customer demand for the Data Sciences service.
Immunic Closes Series A Financing Round
17.5 Million Euro financing will accelerate development of new therapies for patients that suffer from debilitating diseases caused by the immune system.
Santhera Starts Phase III Study with Raxone in DMD
The trial will assess the efficacy of Raxone in slowing the rate of respiratory function decline in Duchenne muscular dystrophy (DMD) patients receiving concomitant glucocorticoids.
Quidel's Solana® Influenza A, B Assay Receives FDA Clearance
The Assay is designed to detect nucleic acids isolated from nasal and nasopharyngeal swabs from patients with signs and symptoms of respiratory infection.
Immunic Acquires 4SC’S Immunology Portfolio
Company has acquired two promising drug development programs with validated targets known to be relevant in various immune and autoimmune diseases.
Amgen's Kyprolis Fails Phase III Trial
Amgen's Kyprolis has failed its 54 week Clarion Phase 3 trial which was evaluating its effectiveness in multiple myeloma patients.
Galapagos Completes Regulatory Consultations to Progress Filgotinib to Phase 3 Study
DIVERSITY Phase 3 study in Crohn’s disease.
ProNAi Licenses Inhibitor from CRT
ProNAi Therapeutics, Inc. has licensed an inhibitor of Checkpoint kinase 1 from CRT Pioneer Fund LP.
MD Anderson Cancer Center, Adaptimmune Form Strategic Alliance
Alliance to expedite development of novel adoptive T-cell therapies for multiple types of cancer.
PAREXEL Announces Agreement to Acquire ExecuPharm
Acquisition will strengthen and add scale to current functional services offering to meet growing demand.
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Events
14th Annual Pharmaceutical IT
28 Sep 2016
14th Annual Pharmaceutical IT ...
Unlocking the potential of syn
27 Sep 2016
Unlocking the potential of syn ...
Quality Excellence: From Quali
28 Sep 2016
Quality Excellence: From Quali ...
Mass Spec 2016 - 13th Symposiu
27 Sep 2016
Mass Spec 2016 - 13th Symposiu ...

ePosters
Development and Application of Quantitative Immunoassays for Major Milk Allergens Bos d 5 (β-lactoglobulin) and Bos d 11 (β-casein)
1. Indoor Biotechnologies, Ltd., Cardiff, Wales, UK. 2. INRA, Gif-sur-Yvette, France

In this study, we sought to develop accurate, sensitive and reliable assays that would enable quantification of multiple milk allergens.
Blood Transcriptomic Diagnosis of Active TB with Five Genes
1Infection & Immunity, University College London, UK 2Department of Microbiology, University College London Hospitals NHS Trust, UK 3Blizard Institute, Queen Mary Univ

This study aimed to identify the minimal set of genes that can accurately diagnose active TB, both pulmonary and extrapulmonary, and evaluate their specificity.
A Novel Benchtop Time-of-Flight GC-MS System for High Performance Analysis of Human Urine
LECO Corporation

A workflow was developed and implemented for the effective comparison of urine. It involved the preparation of stable compounds through derivatization, data acquisition using a high performance benchtop TOFMS, comprehensive data processing (NonTarget Deconvolution™), and quick retrospective analysis of rich datasets using Target Analyte Finding.

Experimental design considerations for efficient and specific gene knockin using a CRISPR-Cas9 for HDR with synthetic crRNA and tracrRNA
Dharmacon, part of GE Healthcare

Precise genome engineering with CRISPR-Cas9 and single-stranded DNA oligo or double-stranded DNA plasmid donors via homology-directed repair (HDR).
Magnetically Manipulated Sample Handling System on Digital Microfluidic Platforms
1Department of Electrical Engineering, C.E.M, Kolaghat, West Bengal 721171, India 2Department of Power Engineering, Jadavpur University, Kolkata 700098, India

Herein we present a proof of concept demonstration of magnetic manipulation of an immiscible, microliter-scale ferrofluid droplet over a thin aqueous film on a solid substrate, using an array of square electromagnets.
Comparison of Key Signaling Pathways in Lung Cancer Cells Grown in 2D and 3D Formats
Western University of Health Sciences

Evaluation of Wnt/ß-catenin and BMP pathway proteins and gene expression in NSCLC cell lines A549 and H460 in 2D and 3D cultures.

Touching BACE. How Inhibiting β-Amyloid Production by Steric Hindrance with a Novel Immunotherapy Improves Memory in PDAPP Mice
1. School of Pharmacy and Pharmaceutical Sciences, 2. School of Psychology Cardiff University, Cardiff, UK

The work presented in this poster aims to assess whether intracerebroventricular (ICV) administration of 2B3 alleviated age dependent memory deficits in PDAPP mice and to determine whether 2B3 altered APP metabolism and NMDA receptor phosphorylation ex vivo.
Exosomes promote survival in squamous head and neck cancer cells after ionizing radiation
Helmholtz Zentrum München, Institute of Radiation Biology, Neuherberg, Germany / Department of Chemistry, Technical University of Munich, Munich, Germany

Exosomes are important intercellular communicators in the acute radiation stress-response. These nanometer-sized extracellular vesicles confer protective signals to neighboring cells and therefore promote the tumorigenic and radioresistant phenotype of head and neck cancer cells.
Multiplexed Cell- and Bead-based Assays in a No-wash Format for Biologics Screening and Characterization
TTP Labtech Inc, One Kendall Square, Suite B2303, Cambridge MA 02139-1594, USA

Here we present the results generated from multiplexed no-wash protocols using TTP Labtech’s mirrorball, a laser scanning cytometer.
Development of a Homogenous RSV Neutralization Assay on the Mirrorball Fluorescence Cytometer: A Simple, Safe and Robust Approach for High-throughput Screening
TTP Labtech Ltd, Melbourn Science Park, Melbourn, Royston, Hertfordshire, SG86EE, UK.

Here we present the development and implementation of a simple RSV-neutralization assay on TTP Labtech’s mirrorball fluorescence cytometer.
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Application Notes
Using DSC to Characterize Thermotropic Phase Transitions in Lipid Bilayer Membranes
Malvern Instruments Limited

The basics of liposome sample preparation and DSC studies.
Monitoring Microfiltration Processes for Water Treatment
Malvern Instruments Limited

Quantifying nanoparticle concentration and size to optimize filtration processes.
Particle Size Analysis of Calcium Carbonates by Laser Diffraction
Malvern Instruments Limited

Calcium Carbonate is used within a wide range of industrial products as a filler and pigment. It is also used as a source of calcium within food and pharmaceutical products. Its function is often related to its particle size and size distribution.
Integrating Automation and DOE to Streamline and Accelerate Quality by Design Activities for Process Chemistry
Unchained Labs

Unchained Labs' tools translate complex experiments into executable methods.
Optimization of a Multi-Mode Detection Model for Measuring Real-time Cellular Respiration and Mitochondrial Function using Fluorophoric Biosensors
BioTek Instruments, Inc.

Cellular metabolism characterization is being aided by the development of new tools designed to provide ease-of-use, higher throughput, and multiplexed data markers for analysis.
Monitoring Saccharomyces Cerevisiea Growth with Bright Field Microscopy in Real Time
BioTek Instruments, Inc.

Strains of the yeast Saccharomyces cerevisiea serve critical roles in the production of many different products including food staples, medicines, and biofuels. The ability to obtain the desired product reliably and repeatedly requires careful monitoring of not only the input materials, but the growth of the yeast strain during the process.
Protein Storage and Stability Analysis Using the Zetasizer Nano ZSP
Malvern Instruments Limited

Spidroins are large, structural proteins that make up the bulk of spider silk fibres. This application note describes the use of a Zetasizer Nano ZSP to characterize their stability at different temperatures.
Preformulation and Stability Studies of Biotherapeutics Using DSC
Malvern Instruments Limited

The Malvern MicroCal VP-Capillary DSC has been used for rapid screening of buffers in preformulation development and for the optimization of storage conditions of antibodies during process development. The results correspond well with those obtained by other more time-consuming methods.
Overcoming and Quantifying ‘Wall Slip’ in Measurements Made on a Rotational Rheometer
Malvern Instruments Limited

When making rheological measurements on structured liquids possible errors may be introduced due to a phenomenon called ‘wall slip. This application note shows how the extent of wall slip can be determined.
A Novel Lipid Screening Platform that Provides a Complete Solution for Lipidomics Research
SCIEX

The Lipidyzer™ Platform, powered by Metabolon®.
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