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Webcasts
A Microfluidic Toolbox for Nucleic Acid Based Diagnostic Tests
Holger Becker, Microfluidic ChipShop GmbH, speaking at Advances in Biodetection & Biosensors 2014
Streamlining Routine Chromatography Analyses using eWorkflows
Darren Barrington-Light, Product Specialist, Thermo Scientific

Market Reports
Gene Expression Analysis Market by Technology, Consumables, Services & Applications - Global Forecast to 2018
MarketsandMarkets

Over the years, the gene expression analysis market, comprising of instruments, consumables, and services, has witnessed various technological advancements. These advancements have led to a growth in the number of gene expression applications.
Epigenetic Modification Screening Trends 2014
HTStec

This market report summarizes the results of HTStec’s 3nd industry-wide global web-based benchmarking survey on epigenetic modification screening carried out in May 2014.
Security Technologies in Biotechnology
RI Technologies

The report serves as a guide to security technology industry for biotechnology applications, covering more than 350 companies that are engaged in security technology/products and services.
ADME/Tox Technologies
RI Technologies

This report on ADME/Tox Technologies gives a market insight into products and services used in the ADME/Tox industry. Predictive technologies analyzed include in vivo, in vitro, and in silico.
Laboratory Information Management System Market in India 2013
Netscribes

The Laboratory Information Management System (LIMS) forms a niche market segment in India presently. The growing systemization of laboratories will gradually steer forth the market. The simultaneous rapid development of Indian healthcare sector that is seeing rise in number of various types of laboratories will propel the future of LIMS adoption in Indian healthcare sector as well.
Big Data Market in India 2013
Netscribes

The report highlights the current as well as the future big data market scenario in India. The report furnishes explicit details on the crucial aspects of the overall market to provide a holistic view, with the aide of crisp and insightful representation of market data.
Life Science Software 2013: Markets and Opportunities
Biopharm Reports

This reports into in the life science field examines the use of specialist software and databases relating to the conduct of PCR, DNA sequencing, DNA microarray, flow cytometry, mass spectrometry and disease biomarker studies. The studies were carried out to assist software developers and vendors to identify market opportunities in these fields.
Back to the Lab! Improving R&D Productivity and Efficiency with LIMS and ELNs
Datamonitor plc

The rigorous R&D processes of pharma and biotech have provided them with a wealth of data, documents and knowledge, but this information is often held in organizational silos, paper laboratory notebooks and disparate IT systems, rendering them virtually useless. Therefore, life sciences companies are implementing LIMS and ELNs to remove the silos and connect R&D groups across the enterprise.
Scientific News
BioClinica and Rutgers University Announce Research Project Results
Scientific Partnership Aims to Expand Automation of Clinical Trial Image Data Analysis
Leading Japanese CRO Standardizes on Thermo Scientific Watson LIMS
JCL Bioassay uses Thermo Scientific Watson LIMS to optimize communication, data management and quality control during U.S. expansion.
How it Works: Advanced Data Analysis Using Visualisation
Visualisation is a powerful tool for those working in molecular biology, here Qlucore offers a five-step method to ensure repeatable and significant results.
Molecular Modelling to Help Create Better, Safer Drugs
How our bodies break down the common drugs ibuprofen, diclofenac and warfarin is the subject of a new study from the University of Bristol.
ATARiS Informatics Platform Hits the Jackpot
ATARiS is one of several tools developed at the Broad Institute to precisely tune in to the signals within noisy datasets.
New Software Spots, Isolates Cyber-attacks to Protect Networked Control Systems
Software algorithm detects and isolates cyber-attacks on networked control systems that are becoming increasingly important to national infrastructure
Genedata Enables Research to Improve Personalized Treatment of Breast and Ovarian Cancer
Genedata collaborates with leading European institutions on the development of blood tests for early detection of major female cancers based on epigenetic markers
Unanticipated Consequences of DNA Hypomethylation; Loss and Gain of Polycomb Mediated Transcription Repression in Somatic Cells
By genome-wide mapping of the Polycomb Repressive Complex 2 (PRC2)-signature histone mark, H3K27me3, in DNA methylation-deficient mouse somatic cells, the Meehan lab shows that loss of DNA methylation is coincident with widespread H3K27me3 redistribution.
Tissue of Origin Determines Cancer-associated CpG Island Promoter Hypermethylation Patterns
Meehan, Sproul and co-workers conclude that general aberrant promoter hypermethylation in cancer does not promote tumorigenesis, but instead reinforces transcription repression inherited from pre-cancerous tissue.
Non-Genotoxic Carcinogen Exposure Induces Defined Changes in the 5-Hydroxymethylome
In a genome wide study Meehan, Moggs and MARCAR co-authors examined 5mC and 5hmC profiles of liver in control and phenobarbital treated mice. They observe dynamic and reciprocal changes in the 5mC/5hmC patterns over genes promoters that are transcriptionally up-regulated.
Business News
ATL to Exhibit Data Automation Solutions at 2014 TCEQ Public Drinking Water Conference
LIMS and lab software solutions to be highlighted
Imperial College, Zhejiang University Launch Data Science Collaboration
Data scientists will team up at a new London lab.
Every Lab is a Regulated Lab… and that may be Good News!
Response to Editor Helen Gillespie's recent editorial on labs and regulations by Joe Liscouski, Executive Director, Institute for Laboratory Automation
ATL to Exhibit Laboratory Automation and LIMS at VA AWWA/VWEA Good Laboratory Practice Conference 2014
ATL will demonstrate Sample Master v10 - a 100 percent web-based LIMS, built on .NET framework.
Grain Processing Corporation Selects Locus Technologies Software for Environmental Management
GPC will use Locus to identify, track, and respond to all environmental media affected by the operations of two of its facilities
New Solutions to Old Challenges
Waters Corporation introduces a new NuGenesis Lab Management System (LMS) that integrates sample management functions and business operations across the enterprise. Technology Networks' Editor Helen Gillespie interviewed Waters' Garrett Mullen for details.
USDM, DocuSign to Help Life Sciences Organizations Go Fully Digital
Partnership helps life sciences firms increase speed to market while ensuring 21 CFR Part 11 compliance.
Agilent to Distribute Cerno's Calibration and Analysis Software with GC/MSD Systems
Novel Program Increases Lab Accuracy and Unknown Compound Identification with Single Quadrupole Instrumentation
Automating Deep Characterization of Biotherapeutic Proteins
Thermo's new PepFinder software streamlines relative and absolute quantitation, and identification of proteins from biological samples using LC-MS.
ATL to Host Webcast on Top Reasons to Consider LIMS as SaaS
Webcast on Wednesday, June 18, 2014, to share information on leveraging LIMS as a Software as a Service (SaaS) model

Events
Metabomeeting 2014
10 Sep 2014
Metabomeeting 2014 ...
More information
Drug Discovery India 2014
11 Sep 2014
Drug Discovery India 2014 ...
More information
Big Data in Pharma
30 Sep 2014
Big Data in Pharma ...
More information
World of Technology & Science
30 Sep 2014
World of Technology & Science ...
More information

ePosters
Automatic Characterization of Lipids Using Charge Remote Fragmentation Ions and Peaks Characteristic of Fatty Acid Fragmentation From MALDI MS/MS Data
(1)PREMIER Biosoft, Indore, India; (2)PREMIER Biosoft, Palo Alto, U.S.A; (3)AB SCIEX, Darmstadt, Germany; (4)AB SCIEX, Framingham, U.S.A.

Automated identification of lipids using CRF ions and high energy MS/MS fragment ions and novel software.
Automatic Characterization of Lipids Using Charge Remote Fragmentation Ions and Peaks Characteristic of Fatty Acid Fragmentation From MALDI MS/MS Data
(1)PREMIER Biosoft, Indore, India; (2)PREMIER Biosoft, Palo Alto, U.S.A; (3)AB SCIEX, Darmstadt, Germany; (4)AB SCIEX, Framingham, U.S.A.

Automated identification of lipids using CRF ions and high energy MS/MS fragment ions and novel software.
Design of Mixed-Criticality Applications on Distributed Real-Time Systems
Technical University of Denmark

In this thesis, we are interested in mixed-criticality applications (both in the safety and time domains) implemented using heterogeneous processing elements (PE) interconnected using TTEthernet. We address the problem of synthesizing mixed-criticality applications on partitioned architectures, at the PE level and at the communication level.
ChemoSoft: a new chemometric software for non-chemometricians
UMR1145 INRA/AgroParisTech

Professional applications such as those provide by some software editors and free downloadable toolboxes developed for Matlab®, R, Octave or Scilab propose many computation tools. But, to our best knowledge, very few are usable by neophytes or anyone that are not skilled with chemometrics or statistics. ChemoSoft is the first chemometric software designed for non-chemometricians.
Rapid Identification of Microorganisms by Touch Spray and Paper Spray Ambient Ionization
Purdue University

The rapid and accurate identification of microorganisms is necessary in order to improve public health. Molecular-based identification allows for rapid patient treatment and provides more accurate diagnoses, two crucial aspects for successful treatment, yet a great challenge. In this work PS-MS, an existing ambient method, and TS-MS, a newly developed technique, are being utilized in the rapid discrimination of microorganisms (<2 min).
Processing and Managing Analytical Data to Extract and Share Knowledge – How Far We’ve Come and Why It’s So Hard?
Advanced Chemistry Development Inc.

This paper discusses the ACD/Spectrus Processor, the new all-in-one analytical data processing and chemical characterization software.
An Integrated Solution for Automated Nanoliter Hit-Picking at BioFocus
1TTP Labtech Ltd 2BioFocus

This poster describes a section of BioFocus’s screening workfolow where mosquito X1 is integrated with a RapidStak plate stacker (Thermo Scientific) using TTP LabTech’s CherryPicker software. This allows the mosquito X1 to work unattended for extended periods. The CherryPicker software drives the system automatically by converting pick lists provided by BioFocus’ LIMS system into mosquito protocols, and feeding appropriate plates via the RapidStak.
Rapid Scale-up of Exome Sequencing Research using a Commercial Lab and Data Management Solution
Genologics

In mid-2009 The Nickerson Lab in the Department of Genome Sciences at the University of Washington faced the daunting task of rapidly scaling up their next generation sequencing laboratory. Given the enormous amount of data to be generated, a critical part of this scale-up was picking the right LIMS solution. This system needed to handle data flow from sample submission to results reporting.
Protein array-based screening of autoantibody signatures
Fondazione Istituto Nazionale Genetica Molecolare

The evidence for an association between autoimmune diseases and chronic HCV infection has been clearly established. To this aim, a protein array was employed to analyze serum samples of HCV patients w/wo autoimmune complications, of patients with autoimmune hepatitis but not infected with HCV and of healthy donors as controls. A panel of autoantigens able to discriminate among the three groups of patients was identified for potential use as biomarkers.
Homology modeling and docking studies of Comamonas testosteroni B-356 biphenyl-2, 3-dioxygenase involved in degradation of polychlorinated biphenyls
Indian Institute of Toxicology Research

The three-dimensional model of a-subunit of Biphenyl dioxygenase (BphA) from Comamonas testosteroni B-356 has been constructed. The kinetic parameters of biphenyl compounds were well matched with the docking results. The binding properties of these biphenyl compounds along with identification of critical active site residues could be used for further site-directed mutagenesis experiments in order to identify their role in activity and substrate specificity.
Application Notes
Global Mining Leader Implements LIMS to Support ISO 17025
STARLIMS

Aspiring to satisfy the criteria for laboratory accreditation, Anglo American Research Labs searched for an ISO 17025 “ready” LIMS. STARLIMS aided in automating the lab to conform to ISO 17025 standards.
The ROI of LIMS Standardization
STARLIMS

Seeking a replacement for their internally developed LIMS, ChevronTexaco selected STARLIMS to standardize five domestic US refinery plants. The system is presently in production concurrently at all five sites, with 2,500 users.
Replacing a Legacy LIMS at the Pacific Environmental Science Centre
STARLIMS

The Pacific Environmental Science Centre (PESC) had been using a LIMS developed in the 1970s but, with multi-functionality required, covering 105 applications, and with 12 functional areas of the laboratory and around 500,000 tests conducted per year, the system was becoming increasingly more difficult and time-consuming to maintain.
Minimizing Compliance Risk at Regulated Nutrient Manufacturer
STARLIMS

Today’s laboratories are struggling to find ways to effectively solve their two most important issues: addressing regulatory compliance, including 21 CFR Part 11, and improving inefficient processes. Fortitech Inc.’s burgeoning task of managing and documenting ingredient blend quality procedures, invoked an initiative to fully automate lab operations.
SDMS Vision Publisher Facilitating Masslynx and Empower Software Data Capture
Waters Corporation

As the volume and complexity of research data continues to grow, the use of an electronic format for laboratory record keeping is the key to simple recording and global communication of critical scientific information.
Flexible Lab and Data Management for the Applied Biosystems SOLiD(TM) Next Generation Sequencing System
Genologics

The Applied Biosystems SOLiDTM system is revolutionizing genetic analysis. Its massively parallel sequencing of clonallyamplified DNA fragments provides accurate, high-throughput results for growing applications in transcriptomics, epigenomics, and whole genome and targeted resequencing, all in one platform.
Flexible Lab and Data Management for the Illumina Genome Analyzer
Genologics

The Illumina Genome Analyzer represents a breakthrough in the volume and quality of genome sequencing. The massive output of Illumina sequencing technology enables even small labs to match the sequencing capabilities of the largest genome centers just years ago. This application note details how Geneus manages the lab and data from a Genome Analyzer resequencing workflow.
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