Thursday, February 23, 2012
Technology Networks
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 | Hospital Integrated Biobanking and Prospective Cancer Biobanking (U-Can) Anna Beskow, Director of Uppsala Biobank, speaking at World Biobanking Summit 2011. |
 | LIMS Deployment: An Integral Component for Manufacturing Operations Excellence Simon Jacobson, Research Director, Gartner, Inc. and Donald Thomas, Director of Technical Service and Quality Programs, CF Industries, Inc. |
SDMS - Unstructured Data Management in the Paperless Lab
Ovum
With the volume of scientific data increasing exponentially year after year, the life sciences industry's need for data-management solutions continues to grow. SDMS solutions continue to evolve and provide organizations with a means of achieving further gains in productivity and efficiency.
Biostorage Trends 2010
HTStec
This market report summarizes the results of HTStec’s global web-based benchmarking survey on biological sample storage carried out in July 2010. The objectives of the study were to comprehensively document current practices and preferences in biological sample storage and to understand future user requirements.
Back to the Lab! Improving R&D Productivity and Efficiency with LIMS and ELNs
Datamonitor plc
The rigorous R&D processes of pharma and biotech have provided them with a wealth of data, documents and knowledge, but this information is often held in organizational silos, paper laboratory notebooks and disparate IT systems, rendering them virtually useless. Therefore, life sciences companies are implementing LIMS and ELNs to remove the silos and connect R&D groups across the enterprise.
Ovum
With the volume of scientific data increasing exponentially year after year, the life sciences industry's need for data-management solutions continues to grow. SDMS solutions continue to evolve and provide organizations with a means of achieving further gains in productivity and efficiency.
Biostorage Trends 2010
HTStec
This market report summarizes the results of HTStec’s global web-based benchmarking survey on biological sample storage carried out in July 2010. The objectives of the study were to comprehensively document current practices and preferences in biological sample storage and to understand future user requirements.
Back to the Lab! Improving R&D Productivity and Efficiency with LIMS and ELNs
Datamonitor plc
The rigorous R&D processes of pharma and biotech have provided them with a wealth of data, documents and knowledge, but this information is often held in organizational silos, paper laboratory notebooks and disparate IT systems, rendering them virtually useless. Therefore, life sciences companies are implementing LIMS and ELNs to remove the silos and connect R&D groups across the enterprise.
SRI Speeds Development of Genome-Scale Models of Metabolic Networks
The new MetaFlux functionality can be used to design drugs against disease-causing bacteria and metabolically engineer bacteria to make chemicals and fuels.
ATL and EnvironmentalReports Partner
Partnership aims to provide laboratories with the ability to manage all operational data and easily achieve regulatory compliance goals
Exemplar LIMS Accelerates Mitomics CLIA Certification and Serves as Foundation of Operations
Phase One of the project encompassed a large scope
Nippon Shinyaku Selects and Deploys the Symyx Notebook by Accelrys
Accelrys Electronic Laboratory Notebook drives R&D efficiency and eases regulatory burdens
Center for Epigenetics (Feinberg Lab) at Johns Hopkins Selects Exemplar LIMS for Epigenetic Research
Sapio Sciences' Exemplar LIMS and ELN solutions to be used for epigenetic studies.
A Bioinformatics Approach for Determining Sample Identity from Different Lanes of High-Throughput Sequencing Data
Verifying that each lane in a genome's build is from the same sample is an important quality control. Researchers from the National Human Genome Research Institute address this issue in a post hoc bioinformatic manner.
GenoLogics Releases White Paper on Increasing NGS Genomics Lab Throughput
GenoLogics has releases a white paper on how to improve lab efficiency and increase throughput with a pre-configured Laboratory Information Management System (LIMS)
Make it Better But Don't Change Anything
A commentary published in Automation Experimentation by Jerry M Wright of John Hopkins School of Medicine examines some of the issues and experiences in academic laboratories that have proved challenging in implementing an electronic laboratory notebook.
LimsPortal and BonsaiLIMS: Development of a Lab Information Management System for Translational Medicine
This article details the design and development of BonsaiLIMS, a LIMS built around a very simple data model that can be easily implemented using a variety of technologies and easily extended as specific requirements dictate.
The Protein Information Management System (PiMS): A Generic Tool for any Structural Biology Research Laboratory
This article describes the Protein Information Management System (PiMS), a LIMS development specifically targeted at the flexible and unpredictable workflows of protein-production research laboratories of all scales.
The new MetaFlux functionality can be used to design drugs against disease-causing bacteria and metabolically engineer bacteria to make chemicals and fuels.
ATL and EnvironmentalReports Partner
Partnership aims to provide laboratories with the ability to manage all operational data and easily achieve regulatory compliance goals
Exemplar LIMS Accelerates Mitomics CLIA Certification and Serves as Foundation of Operations
Phase One of the project encompassed a large scope
Nippon Shinyaku Selects and Deploys the Symyx Notebook by Accelrys
Accelrys Electronic Laboratory Notebook drives R&D efficiency and eases regulatory burdens
Center for Epigenetics (Feinberg Lab) at Johns Hopkins Selects Exemplar LIMS for Epigenetic Research
Sapio Sciences' Exemplar LIMS and ELN solutions to be used for epigenetic studies.
A Bioinformatics Approach for Determining Sample Identity from Different Lanes of High-Throughput Sequencing Data
Verifying that each lane in a genome's build is from the same sample is an important quality control. Researchers from the National Human Genome Research Institute address this issue in a post hoc bioinformatic manner.
GenoLogics Releases White Paper on Increasing NGS Genomics Lab Throughput
GenoLogics has releases a white paper on how to improve lab efficiency and increase throughput with a pre-configured Laboratory Information Management System (LIMS)
Make it Better But Don't Change Anything
A commentary published in Automation Experimentation by Jerry M Wright of John Hopkins School of Medicine examines some of the issues and experiences in academic laboratories that have proved challenging in implementing an electronic laboratory notebook.
LimsPortal and BonsaiLIMS: Development of a Lab Information Management System for Translational Medicine
This article details the design and development of BonsaiLIMS, a LIMS built around a very simple data model that can be easily implemented using a variety of technologies and easily extended as specific requirements dictate.
The Protein Information Management System (PiMS): A Generic Tool for any Structural Biology Research Laboratory
This article describes the Protein Information Management System (PiMS), a LIMS development specifically targeted at the flexible and unpredictable workflows of protein-production research laboratories of all scales.
Pittcon 2012 Preview
Technology Networks will be exhibiting at the upcoming Pittcon Conference & Expo from March 11-15 at booth number 2062 -- near to the Informatics arena. When you visit the Informatics vendors, please stop by!
GenoLogics and Illumina Sign Deal
GenoLogics has signed a worldwide co-selling agreement with Illumina.
StarLIMS wins FDA software deal
The company will supply its lab management solutions for FDA testing laboratories.
LABVANTAGE sits well in Furniture Space
LABVANTAGE has been selected by one of the largest furniture manufacturers in the world. With LABVANTAGE in place, global test labs for this manufacturer will better manage, control, and verify tests conducted on a global level and outside of the enterprise between approved external laboratories and suppliers.
Life Technologies Names Alan Sachs as Head of Global Research and Development
Sachs brings more than 20 years of experience as a research scientist and a leader in developing innovative scientific platforms.
Bruker to Supply Instruments for ThyssenKrupp Stainless USA’s New Plant
Calvert, Alabama-based ThyssenKrupp Stainless USA has placed roughly $1.3 worth of order for Bruker’s automation equipment and elemental analysis systems. These instruments will be installed at ThyssenKrupp’s new advanced stainless steel melt factory.
Global Laboratory Information Management Systems Market to Reach US$1.4 Billion by 2015, According to New Report by Global Industry Analysts, Inc.
GIA announces the release of a comprehensive global outlook on the Laboratory Information Management Systems (LIMS) Industry. Growth in the global LIMS market would be driven by the increasing adoption of LIMS solutions among research organizations in emerging markets. In addition, technological advancements and the growing popularity of SaaS LIMS are expected to enhance adoption.
Abbott’s STARLIMS LIMS Technology to be Installed in FDA Testing Laboratories
STARLIMS and Abbott have announced that the FDA will begin implementing STARLIMS LIMS solution as part of the agency’s initiative to enhance FDA’s testing laboratories.
Oracle® Health Sciences Omics Data Bank Unveiled
The bank addresses big data challenges, integrates and provides analytics for clinical and omics data to accelerate personalized medicine initiatives.
Abbott's STARLIMS LIMS Technology to be Installed in FDA Testing Laboratories
FDA will begin implementing the software-based LIMS as part of the agency's initiative to enhance FDA testing laboratories by managing complex processes and analysing the vast amount of information generated.
Technology Networks will be exhibiting at the upcoming Pittcon Conference & Expo from March 11-15 at booth number 2062 -- near to the Informatics arena. When you visit the Informatics vendors, please stop by!
GenoLogics and Illumina Sign Deal
GenoLogics has signed a worldwide co-selling agreement with Illumina.
StarLIMS wins FDA software deal
The company will supply its lab management solutions for FDA testing laboratories.
LABVANTAGE sits well in Furniture Space
LABVANTAGE has been selected by one of the largest furniture manufacturers in the world. With LABVANTAGE in place, global test labs for this manufacturer will better manage, control, and verify tests conducted on a global level and outside of the enterprise between approved external laboratories and suppliers.
Life Technologies Names Alan Sachs as Head of Global Research and Development
Sachs brings more than 20 years of experience as a research scientist and a leader in developing innovative scientific platforms.
Bruker to Supply Instruments for ThyssenKrupp Stainless USA’s New Plant
Calvert, Alabama-based ThyssenKrupp Stainless USA has placed roughly $1.3 worth of order for Bruker’s automation equipment and elemental analysis systems. These instruments will be installed at ThyssenKrupp’s new advanced stainless steel melt factory.
Global Laboratory Information Management Systems Market to Reach US$1.4 Billion by 2015, According to New Report by Global Industry Analysts, Inc.
GIA announces the release of a comprehensive global outlook on the Laboratory Information Management Systems (LIMS) Industry. Growth in the global LIMS market would be driven by the increasing adoption of LIMS solutions among research organizations in emerging markets. In addition, technological advancements and the growing popularity of SaaS LIMS are expected to enhance adoption.
Abbott’s STARLIMS LIMS Technology to be Installed in FDA Testing Laboratories
STARLIMS and Abbott have announced that the FDA will begin implementing STARLIMS LIMS solution as part of the agency’s initiative to enhance FDA’s testing laboratories.
Oracle® Health Sciences Omics Data Bank Unveiled
The bank addresses big data challenges, integrates and provides analytics for clinical and omics data to accelerate personalized medicine initiatives.
Abbott's STARLIMS LIMS Technology to be Installed in FDA Testing Laboratories
FDA will begin implementing the software-based LIMS as part of the agency's initiative to enhance FDA testing laboratories by managing complex processes and analysing the vast amount of information generated.
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An Integrated Solution for Automated Nanoliter Hit-Picking at BioFocus
1TTP Labtech Ltd 2BioFocus
This poster describes a section of BioFocus’s screening workfolow where mosquito X1 is integrated with a RapidStak plate stacker (Thermo Scientific) using TTP LabTech’s CherryPicker software. This allows the mosquito X1 to work unattended for extended periods. The CherryPicker software drives the system automatically by converting pick lists provided by BioFocus’ LIMS system into mosquito protocols, and feeding appropriate plates via the RapidStak.
Rapid Scale-up of Exome Sequencing Research using a Commercial Lab and Data Management Solution
Genologics
In mid-2009 The Nickerson Lab in the Department of Genome Sciences at the University of Washington faced the daunting task of rapidly scaling up their next generation sequencing laboratory. Given the enormous amount of data to be generated, a critical part of this scale-up was picking the right LIMS solution. This system needed to handle data flow from sample submission to results reporting.
Protein array-based screening of autoantibody signatures
Fondazione Istituto Nazionale Genetica Molecolare
The evidence for an association between autoimmune diseases and chronic HCV infection has been clearly established. To this aim, a protein array was employed to analyze serum samples of HCV patients w/wo autoimmune complications, of patients with autoimmune hepatitis but not infected with HCV and of healthy donors as controls. A panel of autoantigens able to discriminate among the three groups of patients was identified for potential use as biomarkers.
Homology modeling and docking studies of Comamonas testosteroni B-356 biphenyl-2, 3-dioxygenase involved in degradation of polychlorinated biphenyls
Indian Institute of Toxicology Research
The three-dimensional model of a-subunit of Biphenyl dioxygenase (BphA) from Comamonas testosteroni B-356 has been constructed. The kinetic parameters of biphenyl compounds were well matched with the docking results. The binding properties of these biphenyl compounds along with identification of critical active site residues could be used for further site-directed mutagenesis experiments in order to identify their role in activity and substrate specificity.
Homology modeling and docking studies of Comamonas testosteroni B-356 biphenyl-2, 3-dioxygenase involved in degradation of polychlorinated biphenyls
Indian Institute of Toxicology Research
The three-dimensional model of a-subunit of Biphenyl dioxygenase (BphA) from Comamonas testosteroni B-356 has been constructed. The kinetic parameters of biphenyl compounds were well matched with the docking results. The binding properties of these biphenyl compounds along with identification of critical active site residues could be used for further site-directed mutagenesis experiments in order to identify their role in activity and substrate specificity.
Treatment of Plaque Infections and Periodontitis using Stem Cells- A New Prospect
Rajalakshmi Engineering college
Dental precursor cells are attractive for novel approaches to treat diseases like periodontitis, dental caries or to improve dental pulp healing and the regeneration of craniofacial bone and teeth. These cells are easily accessible and, in contrast to bone-marrow-derived mesenchymal stem cells, are more closely related to dental tissues. This paper gives a short overview of stem cells of dental origin.
Treatment of Plaque Infections and Periodontitis using Stem Cells- A New Prospect
Rajalakshmi Engineering college
Dental precursor cells are attractive for novel approaches to treat diseases like periodontitis, dental caries or to improve dental pulp healing and the regeneration of craniofacial bone and teeth. These cells are easily accessible and, in contrast to bone-marrow-derived mesenchymal stem cells, are more closely related to dental tissues. This paper gives a short overview of stem cells of dental origin.
qPCRas a primary screen in drug discovery
MRC -CPE
We report the use of qPCR technique to follow the thermal unfolding of proteins by the binding of the dye SYPRO Orange, and exploit its potential as a robust and high-throughput primary screen for small molecule drug discovery.
DOCKING STUDIES OF A NEW HETEROCYCLIC METHYLTHIOMORPHOLIN PHENOLS DERIVATIVES AS ANTIHYPERTENSIVE DRUGS WITH ACE TARGET.CASE FESCDIPINE II
1.Departamento de C. Químicas FESC, UNAM, 2.Facultad de C. Química UNACH, 3. Facultad de Química, UAEM, 4.Facultad de Medicina UNAM
As part of the Drug Design in Medicinal Chemistry Program of the UNAM, new methylthiomorpholinphenol compounds with cardiovascular effect, were studied. One of them, FESCDIPINE II, was an excellent antihypertensive drug, that has low toxicity and preliminary studies indicate that the Angiotensin-converting enzyme (ACE) system is the biological target of this compound.
3D-QSAR Common Feature Pharmacophore Model for Polyphenols as Potential Anti-Malarial Agents
CDRI
3D QSAR studies have been carried out on a series of polyphenols for their antimalarial activity using CATALYST program. Hypothesis with three features namely hydrophobic (1), hydrogen bond donor (1) and hydrogen bond acceptor (1) was found to the best, which mapped well with the most active and least active compound of the test set. This model can be used to develop drugs for malarial chemotherapy.
1TTP Labtech Ltd 2BioFocus
This poster describes a section of BioFocus’s screening workfolow where mosquito X1 is integrated with a RapidStak plate stacker (Thermo Scientific) using TTP LabTech’s CherryPicker software. This allows the mosquito X1 to work unattended for extended periods. The CherryPicker software drives the system automatically by converting pick lists provided by BioFocus’ LIMS system into mosquito protocols, and feeding appropriate plates via the RapidStak.
Rapid Scale-up of Exome Sequencing Research using a Commercial Lab and Data Management Solution
Genologics
In mid-2009 The Nickerson Lab in the Department of Genome Sciences at the University of Washington faced the daunting task of rapidly scaling up their next generation sequencing laboratory. Given the enormous amount of data to be generated, a critical part of this scale-up was picking the right LIMS solution. This system needed to handle data flow from sample submission to results reporting.
Protein array-based screening of autoantibody signatures
Fondazione Istituto Nazionale Genetica Molecolare
The evidence for an association between autoimmune diseases and chronic HCV infection has been clearly established. To this aim, a protein array was employed to analyze serum samples of HCV patients w/wo autoimmune complications, of patients with autoimmune hepatitis but not infected with HCV and of healthy donors as controls. A panel of autoantigens able to discriminate among the three groups of patients was identified for potential use as biomarkers.
Homology modeling and docking studies of Comamonas testosteroni B-356 biphenyl-2, 3-dioxygenase involved in degradation of polychlorinated biphenyls
Indian Institute of Toxicology Research
The three-dimensional model of a-subunit of Biphenyl dioxygenase (BphA) from Comamonas testosteroni B-356 has been constructed. The kinetic parameters of biphenyl compounds were well matched with the docking results. The binding properties of these biphenyl compounds along with identification of critical active site residues could be used for further site-directed mutagenesis experiments in order to identify their role in activity and substrate specificity.
Homology modeling and docking studies of Comamonas testosteroni B-356 biphenyl-2, 3-dioxygenase involved in degradation of polychlorinated biphenyls
Indian Institute of Toxicology Research
The three-dimensional model of a-subunit of Biphenyl dioxygenase (BphA) from Comamonas testosteroni B-356 has been constructed. The kinetic parameters of biphenyl compounds were well matched with the docking results. The binding properties of these biphenyl compounds along with identification of critical active site residues could be used for further site-directed mutagenesis experiments in order to identify their role in activity and substrate specificity.
Treatment of Plaque Infections and Periodontitis using Stem Cells- A New Prospect
Rajalakshmi Engineering college
Dental precursor cells are attractive for novel approaches to treat diseases like periodontitis, dental caries or to improve dental pulp healing and the regeneration of craniofacial bone and teeth. These cells are easily accessible and, in contrast to bone-marrow-derived mesenchymal stem cells, are more closely related to dental tissues. This paper gives a short overview of stem cells of dental origin.
Treatment of Plaque Infections and Periodontitis using Stem Cells- A New Prospect
Rajalakshmi Engineering college
Dental precursor cells are attractive for novel approaches to treat diseases like periodontitis, dental caries or to improve dental pulp healing and the regeneration of craniofacial bone and teeth. These cells are easily accessible and, in contrast to bone-marrow-derived mesenchymal stem cells, are more closely related to dental tissues. This paper gives a short overview of stem cells of dental origin.
qPCRas a primary screen in drug discovery
MRC -CPE
We report the use of qPCR technique to follow the thermal unfolding of proteins by the binding of the dye SYPRO Orange, and exploit its potential as a robust and high-throughput primary screen for small molecule drug discovery.
DOCKING STUDIES OF A NEW HETEROCYCLIC METHYLTHIOMORPHOLIN PHENOLS DERIVATIVES AS ANTIHYPERTENSIVE DRUGS WITH ACE TARGET.CASE FESCDIPINE II
1.Departamento de C. Químicas FESC, UNAM, 2.Facultad de C. Química UNACH, 3. Facultad de Química, UAEM, 4.Facultad de Medicina UNAM
As part of the Drug Design in Medicinal Chemistry Program of the UNAM, new methylthiomorpholinphenol compounds with cardiovascular effect, were studied. One of them, FESCDIPINE II, was an excellent antihypertensive drug, that has low toxicity and preliminary studies indicate that the Angiotensin-converting enzyme (ACE) system is the biological target of this compound.
3D-QSAR Common Feature Pharmacophore Model for Polyphenols as Potential Anti-Malarial Agents
CDRI
3D QSAR studies have been carried out on a series of polyphenols for their antimalarial activity using CATALYST program. Hypothesis with three features namely hydrophobic (1), hydrogen bond donor (1) and hydrogen bond acceptor (1) was found to the best, which mapped well with the most active and least active compound of the test set. This model can be used to develop drugs for malarial chemotherapy.
Chromatography Workflow with Nexxis iLAB
Labtronics Inc..
In a non-integrated lab, chromatography work flow - from sample login through to reporting of results - consists of a series of separate events that are either manual, paper based processes or take place in applications that are not connected to each other.
Using LimsLink to Create an Instrument Utilization Report
Labtronics Inc..
Instrument Utilization can be defined as gaining a better understanding of how efficiently an instrument is used. An instrument utilization report will show you the amount of time an instrument is actively used for any given time period.
SDMS Vision Publisher Facilitating Masslynx and Empower Software Data Capture
Waters Corporation
As the volume and complexity of research data continues to grow, the use of an electronic format for laboratory record keeping is the key to simple recording and global communication of critical scientific information.
Flexible Lab and Data Management for the Applied Biosystems SOLiD(TM) Next Generation Sequencing System
Genologics
The Applied Biosystems SOLiDTM system is revolutionizing genetic analysis. Its massively parallel sequencing of clonallyamplified DNA fragments provides accurate, high-throughput results for growing applications in transcriptomics, epigenomics, and whole genome and targeted resequencing, all in one platform.
Flexible Lab and Data Management for the Illumina Genome Analyzer
Genologics
The Illumina Genome Analyzer represents a breakthrough in the volume and quality of genome sequencing. The massive output of Illumina sequencing technology enables even small labs to match the sequencing capabilities of the largest genome centers just years ago. This application note details how Geneus manages the lab and data from a Genome Analyzer resequencing workflow.
Labtronics Inc..
In a non-integrated lab, chromatography work flow - from sample login through to reporting of results - consists of a series of separate events that are either manual, paper based processes or take place in applications that are not connected to each other.
Using LimsLink to Create an Instrument Utilization Report
Labtronics Inc..
Instrument Utilization can be defined as gaining a better understanding of how efficiently an instrument is used. An instrument utilization report will show you the amount of time an instrument is actively used for any given time period.
SDMS Vision Publisher Facilitating Masslynx and Empower Software Data Capture
Waters Corporation
As the volume and complexity of research data continues to grow, the use of an electronic format for laboratory record keeping is the key to simple recording and global communication of critical scientific information.
Flexible Lab and Data Management for the Applied Biosystems SOLiD(TM) Next Generation Sequencing System
Genologics
The Applied Biosystems SOLiDTM system is revolutionizing genetic analysis. Its massively parallel sequencing of clonallyamplified DNA fragments provides accurate, high-throughput results for growing applications in transcriptomics, epigenomics, and whole genome and targeted resequencing, all in one platform.
Flexible Lab and Data Management for the Illumina Genome Analyzer
Genologics
The Illumina Genome Analyzer represents a breakthrough in the volume and quality of genome sequencing. The massive output of Illumina sequencing technology enables even small labs to match the sequencing capabilities of the largest genome centers just years ago. This application note details how Geneus manages the lab and data from a Genome Analyzer resequencing workflow.
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