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Videos
Intelligent Flying Robots, University of...
i-Series (HPLC system)...Empower 3 Chromatography Data Software: ...IBM Watson / MSK Collaboration...

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Webcasts
Managing Pharmaceutical Lab Data Management to Ensure Compliance
Join Stacey Brown and William Leonard, Senior Validation Analysts for Informatics at Thermo Fisher Scientific, to understand more about the complex requirements of pharmaceutical data management.
15 Years HCS: Next Gen Screening Devices Learn from Each Other. Literally. Fast Workflow Development & BigData Image Analytics Used to be a Challenge. What’s Next?
Urban Liebel, ACQUIFER, speaking at Screening Europe 2015

Market Reports
Mobile Technology In The Lab Trends 2015
HTStec Limited

This market report summarizes the results of HTStec’s industry-wide global web-based benchmarking survey on the use of mobile technology to monitor and control of lab instruments and automated systems carried out in April 2015.
Epigenetic Modification Screening Trends 2014
HTStec

This market report summarizes the results of HTStec’s 3nd industry-wide global web-based benchmarking survey on epigenetic modification screening carried out in May 2014.
Back to the Lab! Improving R&D Productivity and Efficiency with LIMS and ELNs
Datamonitor plc

The rigorous R&D processes of pharma and biotech have provided them with a wealth of data, documents and knowledge, but this information is often held in organizational silos, paper laboratory notebooks and disparate IT systems, rendering them virtually useless. Therefore, life sciences companies are implementing LIMS and ELNs to remove the silos and connect R&D groups across the enterprise.
Scientific News
What Makes a Good Scientist?
It’s the journey, not just the destination that counts as a scientist when conducting research.
Pittcon 2016: Accelerating Innovation And Enhancing Productivity With Technology
Collaboration and externalization of data highlight evolving lab operations.
Editing of LIMS Data Made Faster and More Efficient in Matrix Gemini
The latest version of the Matrix Gemini LIMS (Laboratory Information Management System) from Autoscribe Informatics now provides faster and more efficient editing of LIMS data by eliminating the need for a second editing screen.
Breaking Through the Barriers to Lab Innovation
Here we examine the drivers behind the move for greater innovation, the challenges and current trends in laboratory informatics, and the tools that can be used to break these barriers.
Researchers Construct Atomic Model of an Immature Retrovirus
Using molecular modeling and large-scale molecular dynamic simulation, Beckman researchers have constructed an atomic model of an immature retrovirus.
New Mathematics Advances the Frontier of Macromolecular Imaging
Berkeley Lab’s M-TIP solves the reconstruction problem for fluctuation X-ray scattering.
Exploring Living cells
JPK reports the exploration of living cells using nanoscale and single molecule techniques through the application of scanning probe microscopy.
The Perfect Partnership: Research & Industry; Software & Instrumentation. It really starts to come together at ASMS 2015
Collaboration and knowledge-sharing were evident everywhere: on the bus, in the hallways and in the bars. This article aims to capture this theme and share with you some of the fruits of this coming together of science and industry.
Designing New Pain Relief Drugs
Researchers have identified the molecular interactions that allow capsaicin to activate the body’s primary receptor for sensing heat and pain, paving the way for the design of more selective and effective drugs to relieve pain.
Antibody Pries Loose Bacteria’s Grip
Study finds novel method of improving antibody efficacy.
Business News
NIH-Funded Center to Study Inefficiencies in Clinical Trials
Researchers at the Duke Clinical Research Institute (DCRI) and Vanderbilt University Medical Center (VUMC) have received a major federal grant to study how multisite clinical trials of new drugs and therapies in children and adults can be conducted more rapidly and efficiently.
Agilent to Acquire iLab Solutions
Companies have announced they have signed a definitive agreement under which Agilent will acquire substantially all of the assets of iLab, the market leader in cloud-based solutions for core laboratory management.
Autoscribe Informatics Appoints Distributor for France, Italy & Switzerland
Autoscribe Informatics has appointed Ritme as its distributor for the Matrix Gemini Laboratory Information Management System (LIMS) in France, Italy and Switzerland. Ritme has been selling scientific software and offering software support since 1989, with the prime objective of helping its customers make the best use of their software solutions.
Helsinki Chemicals Forum Examines the Relationship of Chemicals to the Circular Economy
Forum addresses economic development and sustainability with a particular emphasis on the opportunities and challenges the circular economy poses for chemicals regulation.
Clinical Genomics Announces Implementation of UNIConnect pMDx™ LIMS
The software system will facilitate comprehensive automation of all laboratory processes from sample accessioning through final clinical result reporting.
Sunquest Laboratory v8.0 Released
New version includes significant enhancements to Sunquest Blood Bank.
Frontage Bioanalytical Labs Go Paperless with IDBS
Company has used cutting-edge technology and a single informatics platform with E-Workbook 10 to facilitate validated method execution and asset tracking across the organization.
LABWORKS LIMS Acquired By PerkinElmer
Company has announced that it has acquired the LABWORKS LIMS product line from PerkinElmer Health Sciences.
Titian Software, HighRes Biosolutions Collaborate
Collaboration aims to close a gap in compound management information flow.
LabVantage Moves to iomart Hybrid Cloud
iomart has migrated LabVantage Solutions, Inc., the leading global laboratory informatics provider, to a new customised hybrid cloud platform.

Events
THE DATA INTEGRITY 2016 – ASIA
01 Sep 2016
THE DATA INTEGRITY 2016 – ASIA ...
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14th Annual Pharmaceutical IT
28 Sep 2016
14th Annual Pharmaceutical IT ...
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The Tech Expo 2016 - Explore &
24 Oct 2016
The Tech Expo 2016 - Explore & ...
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FinTech Expo
25 Oct 2016
FinTech Expo ...
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ePosters
Platform Agnostic Data Processing Routine for Targeted and Untargeted Metabolite Identification in Drug Discovery
1Advanced Chemistry Development, Inc. (ACD/Labs), 8 King Street East, Toronto, ON. M5C 1B5. Canada; 2ACD/Labs, Moscow, Russia

A discussion of a new informatics solution that addresses common challenges in metabolite identification and characterization--from LC/MS data processing and metabolites prediction to reporting and databasing of assembled biotransformation knowledge.
Deep Phenotyping - Harnessing Data Richness for Unsupervised High-Content Analysis
Institute of high performance Computing, Astar

Recognising the key challenges, we develop an end-to-end computational framework for HCA dubbed “Deep Phenotyping” that perform unsupervised analysis to leverage on the data richness for the discovery of unknown sub-phenotypes with minimal labeling cost.
The Case for CASE: Computer-Assisted Structure Elucidation
ACD/Labs

Modern CASE systems such as Structure Elucidator Suite provide the necessary capability accurately elucidate a novel chemical structure for complex molecules based on readily available NMR data sets. This allows organizations to avoid expensive, labor-intensive, and time-consuming synthetic efforts.
A Unified Software Platform for Laboratory Informatics
Advanced Chemistry Development, Inc. (ACD/Labs), Toronto, Canada.

Reported here are capabilities in automated workflows involving analytical data with chemical structures. Specifically described is automated homogenization of data from a set of instruments, including NMR structure verification, as one solution.
Addressing False Positive Variants Arising from Pseudogenes
1National Heart and Lung Institute, Imperial College, London, UK, 2NIHR Cardiovascular BRU, Royal Brompton and Harefield NHS Trust, London, UK, 3Royal Brompton and Har

Clinical genetic testing has been transformed in recent years by the introduction of Next-Generation Sequencing (NGS).
PredRet: Prediction of Retention Time by Direct Mapping between Multiple Chromatographic Systems
Department of Food Quality and Nutrition, Research and Innovation Centre, Fondazione Edmund Mach, San Michele all’Adige (TN), Italy.; Department of Stress and Developmental Biology, Leibniz Institute

Retention time (RT) information is under-utilized in LC-MS based metabolomics and sharing of RTs between systems is not currently possible. PredRet is a new system that allows highly accurate mapping and prediction of RTs between LC systems.
Building a digital pathology ecosystem for education and research
Department of Pathology, Faculty of Medicine, Vrije Universiteit Brussel; Department of Pathology, University Hospital Brussels

We wanted to build a core digital pathology infrastructure to support different use cases. Various images platforms needed to be accessible through a single access point, and support different user profiles. We wanted a scalable solution that would allow interaction between equipment from different research groups.
We built a centralized infrastructure that integrates a variety of imaging platforms, and now have an interconnected network of heterogeneous and scalable information silos.
Predicting Regioselectivityand Labilityof Cytochrome P450 Metabolism using Quantum Mechanical Simulations
Optibrium

Predicting Regioselectivity and Lability of Cytochrome P450 Metabolism using Quantum Mechanical Simulations
The Power Decoder simulator for the evaluation of pooled shRNA screen performance
GE Healthcare Dharmacon, Inc.

Power Decoder (written in R and Python) simulates shRNA pooled screening experiments in silico to allow for the estimation of a screen’s statistical power. Populations of shRNAs were engineered in such a way that the magnitude of depletion and enrichment was known, then using the negative binomial distribution, an in silico model was developed to successfully resemble data from an actual laboratory experiment.
Knockdown of long noncoding RNAs in breast cancer
GE Healthcare Dharmacon, Inc.

RNAi global collaboration study using Lincode siRNA in a primary screen of tumor and nontumor breast cell lines. Hundreds of lncRNAs are found to affect viability and cell morphology of breast cancer. Presented at Keystone Symposia on Long Noncoding RNAs: From Evolution to Function, Mar 15 - Mar 20, 2015.
Application Notes
Global Mining Leader Implements LIMS to Support ISO 17025
STARLIMS

Aspiring to satisfy the criteria for laboratory accreditation, Anglo American Research Labs searched for an ISO 17025 “ready” LIMS. STARLIMS aided in automating the lab to conform to ISO 17025 standards.
The ROI of LIMS Standardization
STARLIMS

Seeking a replacement for their internally developed LIMS, ChevronTexaco selected STARLIMS to standardize five domestic US refinery plants. The system is presently in production concurrently at all five sites, with 2,500 users.
Replacing a Legacy LIMS at the Pacific Environmental Science Centre
STARLIMS

The Pacific Environmental Science Centre (PESC) had been using a LIMS developed in the 1970s but, with multi-functionality required, covering 105 applications, and with 12 functional areas of the laboratory and around 500,000 tests conducted per year, the system was becoming increasingly more difficult and time-consuming to maintain.
Minimizing Compliance Risk at Regulated Nutrient Manufacturer
STARLIMS

Today’s laboratories are struggling to find ways to effectively solve their two most important issues: addressing regulatory compliance, including 21 CFR Part 11, and improving inefficient processes. Fortitech Inc.’s burgeoning task of managing and documenting ingredient blend quality procedures, invoked an initiative to fully automate lab operations.
SDMS Vision Publisher Facilitating Masslynx and Empower Software Data Capture
Waters Corporation

As the volume and complexity of research data continues to grow, the use of an electronic format for laboratory record keeping is the key to simple recording and global communication of critical scientific information.
Flexible Lab and Data Management for the Applied Biosystems SOLiD(TM) Next Generation Sequencing System
Genologics

The Applied Biosystems SOLiDTM system is revolutionizing genetic analysis. Its massively parallel sequencing of clonallyamplified DNA fragments provides accurate, high-throughput results for growing applications in transcriptomics, epigenomics, and whole genome and targeted resequencing, all in one platform.
Flexible Lab and Data Management for the Illumina Genome Analyzer
Genologics

The Illumina Genome Analyzer represents a breakthrough in the volume and quality of genome sequencing. The massive output of Illumina sequencing technology enables even small labs to match the sequencing capabilities of the largest genome centers just years ago. This application note details how Geneus manages the lab and data from a Genome Analyzer resequencing workflow.
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