Corporate Banner
Satellite Banner
Metabolomics & Lipidomics
Scientific Community
Become a Member | Sign in
Home>News>This Article

New XFe96 Spheroid Microplate from Seahorse Bioscience

Published: Tuesday, April 22, 2014
Last Updated: Thursday, April 24, 2014
Bookmark and Share
The microplate enables functional, metabolic measurement of in vitro tumor spheroids.

This unique 96-well plate features geometry that enables functional, metabolic measurements of individual spheroids for the study of three-dimensional cell culture, which more closely mimics in vivo conditions. Of particular importance for tumor studies, the real-time metabolism of multicellular spheroids can now be analyzed and used for evaluating the metabolic response to therapeutic agents.

“Our customers indicated a need for three-dimensional assay capability but they did not have a measurement tool until now,” explains Brian P. Dranka, Ph.D., manager of biology for Seahorse Bioscience. “Using the XFe96 Spheroid Microplate and the XFe96 Extracellular Flux Analyzer, scientists can now obtain sensitive and reproducible data from individual spheroids with high specificity.”

The XFe96 Extracellular Flux Analyzer simultaneously measures the two major energy-producing pathways within the cell ¬¬– mitochondrial respiration and glycolysis – in a microplate, in real time. The XFe96 Analyzer and Stress Test Kits standardize the measurement of mitochondrial function and glycolysis. The addition of the XFe96 Spheroid Microplate further advances the study of cell metabolism, helping scientists better understand the connection of physiological traits of cells with genomic and proteomic data. This knowledge will generate new insights into cell metabolism and mitochondrial function, leading to a greater understanding and new treatments of diseases including cancer.

The XFe96 Spheroid FluxPak contains six cartridges, six microplates and calibrant. The new plates will be ready for orders and shipment at the beginning of May.

Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,800+ scientific posters on ePosters
  • More than 4,000+ scientific videos on LabTube
  • 35 community eNewsletters

Sign In

Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Seahorse Bio, Moffitt to Develop Method for Measuring Metabolism of 3D Microtissue
The study will focus on non-small cell lung cancers.
Tuesday, October 28, 2014
Seahorse Bioscience, UAB Announce Personalized Medicine Partnership
Partnership agreed to study the bioenergetic health of cells in cryo-preserved blood – a step that will ultimately produce a first-of-its-kind clinical test of metabolic bioenergetic health.
Wednesday, October 15, 2014
Scientific News
Gut Microbes Signal to the Brain When They're Full
Don't have room for dessert? The bacteria in your gut may be telling you something.
Turning up the Tap on Microbes Leads to Better Protein Patenting
Mining millions of proteins could become faster and easier with a new technique that may also transform the enzyme-catalyst industry, according to University of California, Davis, researchers.
Drug May Prevent Life-Threatening Muscle Loss in Advanced Cancers
New data describes how an experimental drug can stop life-threatening muscle wasting (cachexia) associated with advanced cancers and restore muscle health.
Cancer-Fighting Tomato Component Traced
The metabolic pathway associated with lycopene, the bioactive red pigment found in tomatoes, has been traced by researchers at the University of Illinois.
Circadian Clock Controls Insulin and Blood Sugar in Pancreas
Map of thousands of genes suggests new therapeutic targets for diabetes.
Cellular Stress Process Identified in Cardiovascular Disease
Combining the investigative tools of genetics, transcriptomics, epigenetics and metabolomics, a Duke Medicine research team has identified a new molecular pathway involved in heart attacks and death from heart disease.
Predicting Adverse Drug Reactions with Higher Confidence
A new integrated computational method helps predicting adverse drug reaction—which are often lethal—more reliably than with traditional computing methods.
A New Way to Starve Lung Cancer?
Metabolic alterations in lung cancer may open new avenues for treating the disease.
Evidence of How Incurable Cancer Develops
Researchers in the West Midlands have made a breakthrough in explaining how an incurable type of blood cancer develops from an often symptomless prior blood disorder.
Building a Better Liposome
Computational models suggest new design for nanoparticles used in targeted drug delivery.
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,800+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,000+ scientific videos