Corporate Banner
Satellite Banner
Metabolomics & Lipidomics
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Study: Can Vitamin D Slow Heart Complications from Diabetes?

Published: Thursday, May 15, 2014
Last Updated: Thursday, May 15, 2014
Bookmark and Share
Researchers evaluate whether vitamin D can slow the development of cardiovascular problems in African Americans.

Researchers at Washington University School of Medicine in St. Louis are evaluating whether vitamin D can slow the development of cardiovascular problems in African Americans with diabetes. They are more likely to die from cardiovascular disease than Caucasians with diabetes.

The researchers are seeking to enroll about 90 African Americans who are 45 to 80 years old and have type 2 diabetes. Study volunteers must not have heart disease or have suffered a stroke.

“Cardiovascular disease is a major health problem and cause of mortality in African Americans,” said Carlos Bernal-Mizrachi, MD, the study’s principal investigator. “Compared to Caucasians, African Americans suffer disproportionately from type 2 diabetes and heart disease.”

Nationally, African Americans with diabetes are 36 percent more likely than Caucasians with diabetes to die of cardiovascular disease. In past studies, Bernal-Mizrachi has found that low levels of vitamin D can double the risk of cardiovascular disease in patients with type 2 diabetes. His research also shows that blood vessels near the heart are less likely to clog in people who get adequate levels of the key vitamin.

Study volunteers will be screened at the School of Medicine to determine their vitamin D status. Those with low vitamin D levels will be asked to return for a second assessment, during which investigators will evaluate participants’ risk for coronary heart disease by measuring electrolyte levels, kidney function, blood cell counts, average blood sugar levels and cholesterol levels.

“In general, vitamin D deficiency is more common among African Americans, and that may help explain why they are so much more likely than Caucasians to have severe cardiovascular complications related to diabetes,” said Bernal-Mizrachi, associate professor of medicine and of cell biology and physiology.

Volunteers who meet the study’s criteria will be randomly assigned to one of two groups. Those in the first group will take 600 international units of vitamin D daily to try to raise their levels of the vitamin to the standard recommended for good health. Participants in the second study group will take 4,000 international units of the vitamin daily.

Subjects will be evaluated about every two months to measure blood sugar levels, hypertension, heart function and various markers of inflammation - all risk factors for heart disease.

“Compared to other potential interventions, vitamin D is very inexpensive and doesn’t have many known side effects,” said Bernal-Mizrachi. “We believe vitamin D could have a very big impact if the study shows that it can prevent or delay heart problems in African Americans with diabetes.”


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,900+ scientific posters on ePosters
  • More than 4,200+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Patti Wins Sloan Research Fellowship
Award honors outstanding early-career scientists.
Thursday, February 20, 2014
Scientific News
Cancer Cells Kill Off Healthy Neighbours
Cancer cells create space to grow by killing off surrounding healthy cells, according to UK researchers working with fruit flies.
Future of Medicine Could be Found in a Tiny Crystal Ball
A Drexel University materials scientist has discovered a way to grow a crystal ball in a lab. Not the kind that soothsayers use to predict the future, but a microscopic version that could be used to encapsulate medication in a way that would allow it to deliver its curative payload more effectively inside the body.
Toxicity Testing With Cultured Liver Cells
Microreactor replaces animal testing.
Proteins Seek, Attack, Destroy Tumor Cells in Bloodstream
Using white blood cells to ferry potent cancer-killing proteins through the bloodstream virtually eliminates metastatic prostate cancer in mice, Cornell researchers have confirmed.
Why Do Some Infections Persist?
In preparing for the possibility of an antibiotic onslaught, some bacterial cultures adopt an all-for-one/one-for-all strategy that would make a socialist proud, University of Vermont researchers have found.
Flipping Molecular 'Switch' May Reduce Nicotine's Effects in the Brain
Scientists at The Scripps Research Institute (TSRI) have discovered that a lipid (fat molecule) in brain cells may act as a “switch” to increase or decrease the motivation to consume nicotine.
TSRI Team Comes Together with Rare Disease Community
Don’t worry, science fiction fans, the machines aren’t taking over quite yet. It turns out humans still beat computers at reading and comprehending text.
Magnesium Intake May Reduce Pancreatic Cancer Risk
Indiana University researchers have found that magnesium intake may be beneficial in preventing pancreatic cancer.
Gut Microbes: Burning Calories While You Sleep?
Study links changes in gut bacteria to lower resting metabolic rate and weight gain in mice.
Cooperating Bacteria Isolate Cheaters
Bacteria, which reciprocally exchange amino acids, stabilize their partnership on two-dimensional surfaces and limit the access of non-cooperating bacteria to the exchanged nutrients.
SELECTBIO

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,900+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,200+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!