Corporate Banner
Satellite Banner
Metabolomics & Lipidomics
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Study: Can Vitamin D Slow Heart Complications from Diabetes?

Published: Thursday, May 15, 2014
Last Updated: Thursday, May 15, 2014
Bookmark and Share
Researchers evaluate whether vitamin D can slow the development of cardiovascular problems in African Americans.

Researchers at Washington University School of Medicine in St. Louis are evaluating whether vitamin D can slow the development of cardiovascular problems in African Americans with diabetes. They are more likely to die from cardiovascular disease than Caucasians with diabetes.

The researchers are seeking to enroll about 90 African Americans who are 45 to 80 years old and have type 2 diabetes. Study volunteers must not have heart disease or have suffered a stroke.

“Cardiovascular disease is a major health problem and cause of mortality in African Americans,” said Carlos Bernal-Mizrachi, MD, the study’s principal investigator. “Compared to Caucasians, African Americans suffer disproportionately from type 2 diabetes and heart disease.”

Nationally, African Americans with diabetes are 36 percent more likely than Caucasians with diabetes to die of cardiovascular disease. In past studies, Bernal-Mizrachi has found that low levels of vitamin D can double the risk of cardiovascular disease in patients with type 2 diabetes. His research also shows that blood vessels near the heart are less likely to clog in people who get adequate levels of the key vitamin.

Study volunteers will be screened at the School of Medicine to determine their vitamin D status. Those with low vitamin D levels will be asked to return for a second assessment, during which investigators will evaluate participants’ risk for coronary heart disease by measuring electrolyte levels, kidney function, blood cell counts, average blood sugar levels and cholesterol levels.

“In general, vitamin D deficiency is more common among African Americans, and that may help explain why they are so much more likely than Caucasians to have severe cardiovascular complications related to diabetes,” said Bernal-Mizrachi, associate professor of medicine and of cell biology and physiology.

Volunteers who meet the study’s criteria will be randomly assigned to one of two groups. Those in the first group will take 600 international units of vitamin D daily to try to raise their levels of the vitamin to the standard recommended for good health. Participants in the second study group will take 4,000 international units of the vitamin daily.

Subjects will be evaluated about every two months to measure blood sugar levels, hypertension, heart function and various markers of inflammation - all risk factors for heart disease.

“Compared to other potential interventions, vitamin D is very inexpensive and doesn’t have many known side effects,” said Bernal-Mizrachi. “We believe vitamin D could have a very big impact if the study shows that it can prevent or delay heart problems in African Americans with diabetes.”


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,500+ scientific posters on ePosters
  • More than 5,000+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Living Off the Fat of the Land
Do cancer cells synthesize the parts for new cells or scavenge them from the environment?
Tuesday, April 05, 2016
Patti Wins Sloan Research Fellowship
Award honors outstanding early-career scientists.
Thursday, February 20, 2014
Scientific News
Gene Deletion Reveals Cell Secrets
Researchers have deleted 174 genes in yeast to analyse the effect of individual gene deletion.
Targeting Fat to Treat Cancer
Researchers develop novel cancer treatment that halts fat synthesis in cells, stunting tumors.
NIH Study Finds Link Between Depression, Gestational Diabetes
Researchers at NIH have discovered that the depression in early pregnancy doubles risk for gestational diabetes, and gestational diabetes increases risk for postpartum depression.
Gut Pathogens Thrive on Body's Tissue-Repair Mechanism
Researcher have discovered that harm caused by pathogens in the intestinal tract benefit from immune system response to damaged intestinal lining.
Cancer's Taste for Fat
Researchers discovered signalling pathway for fat burning is disrupted in certain cancers.
‘Tracking Bugs’ Reveal Secret of Cancer Cell Metabolism
Unexpected finding shows instead of throwing away valuable nutrients, the cells squeeze out every last drop of energy.
Ginger Nano-Lipid Particles May Improve Cancer Treatment
Edible ginger-derived nano-lipids show promise for effectively targeting and delivering chemotherapeutic drugs used to treat colon cancer.
Genetic Diversity of Enzymes Alters Metabolic Individuality
ToMMo scientists have shown that genetic polymorphisms, structural location of mutation and effect for phenotype correlate with each other.
Absolute Quantification of Mitochondrial Metabolites
Scientists have developed a method to quickly isolate and systematically measure metabolite concentrations within mitochondria.
Vitamin C May Boost Leukemia Treatment
Studies show that supplementing an epigenetic cancer drug with vitamin C enhanced the drug's effectiveness.
Skyscraper Banner

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,500+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
5,000+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!