Wednesday, March 12, 2014
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The Role of Mass Spectrometry in the "Omics" Era
The tremendous developments of the MS technology and concurrent gene sequencing efforts have made the “-omic” revolution possible.
Metabolomics: Taking Aim at Diabetic Kidney Failure
Krolewski and his Joslin colleagues search for better ways of predicting which diabetic people are at risk for ESRD.
Omega-3 Fatty Acids have Wider Range of Biological Impacts
Study explored the challenges the liver faces from the “Western diet” that increasingly is linked to liver inflammation, fibrosis, cirrhosis and sometimes liver failure.
Speeding Validation of Disease Targets
NIH, industry and non-profits join forces to develop new treatments earlier, beginning with Alzheimer’s, type 2 diabetes, and autoimmune disorders.
Fatty Liver Disease Reversed in Mice
Epilepsy drug also shown to decrease obesity-related blood sugar levels.
GW Receives up to $14.6M to Develop Method for Characterizing Security Threats
The researchers are tasked with reducing to 30 days a process that can sometimes take years or even decades.
Metabolomics Reveals a Role for the Chromatin-Binding Protein HMGN5 in Glutathione Metabolism
This study links the expression of HMGN5 to transcriptional changes that affect glutathione metabolism in the liver.
Correlation between Serum Levels of Protein-Bound Uremic Toxins in Hemodialysis Patients Measured by LC/MS/MS
Mass spectrometry has been successfully applied for the identification and quantification of uremic toxins.
Lipidomic Mass Spectrometry and its Application in Neuroscience
This review presents an overview of MS techniques that enable the identification and relative quantitation of cellular lipidome with a brief discussion on their utility for neuroscience related research.
Innovative Screening Strategy Swiftly Uncovers New Drug Candidates, New Biology
Method has been utilised to identify compound with promise for obesity-linked diabetes.
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