The AB SCIEX TripleTOF® 5600+ System is an innovative breakthrough in LC/MS/MS performance that uniquely integrates comprehensive qualitative exploration, rapid profiling, and high-resolution quantitation workflows on a single platform. It combines the highest sensitivity detection, high-resolution with the fastest acquisition speeds, and stable ~2ppm mass accuracy over days of acquisition.
Expanding upon the capabilities of TripleTOF technology, 5600+ provides broader applicability in pharma and a new paradigm in proteomics research.
MS/MSALL with SWATHTM Acquisition - enabling comprehensive MS/MS quantitation in proteomics
Tools for 21 CFR 11 Compliance in Analyst® TF 1.6 and MultiQuantTM Software, bringing the power of accurate mass to regulated bioanalysis
Optional SelexIONTM Technology - for an additional dimension of separation
High resolution at unparalleled speed - up to 40,000 FWHM with 10 msec accumulation time
EasyMassTM Accuracy - without continuous recalibration - over 50 hours of continuous LC/MS operation provides <2 ppm RMS
SmartSpeedTM 100Hz Acquisition delivering high-resolution for high-speed chromatography - up to 100 spectra in a second – even in Information Dependent Acquisition (IDA).
Most sensitive high resolution system - lowest limits of quantitation (LOQ) for a high resolution system and equivalent to high-performance triple quads.
Charting Kidney Cancer Metabolism Changes in cell metabolism are increasingly recognized as an important way tumors develop and progress, yet these changes are hard to measure and interpret. A new tool designed by MSK scientists allows users to identify metabolic changes in kidney cancer tumors that may one day be targets for therapy.Cytoskeleton Crew Findings confirm sugar's role in helping cancers survive by changing cellular architecture.Microbiome May Hold the Key to Fighting Obesity In a unique study of free-ranging brown bears, Swedish researchers were able to show that the bears’ dietary variation goes hand-in-hand with dramatic changes in the animal’s gut microbiota.Cancer Cells Kill Off Healthy Neighbours Cancer cells create space to grow by killing off surrounding healthy cells, according to UK researchers working with fruit flies.Future of Medicine Could be Found in a Tiny Crystal Ball A Drexel University materials scientist has discovered a way to grow a crystal ball in a lab. Not the kind that soothsayers use to predict the future, but a microscopic version that could be used to encapsulate medication in a way that would allow it to deliver its curative payload more effectively inside the body.Toxicity Testing With Cultured Liver Cells Microreactor replaces animal testing. Proteins Seek, Attack, Destroy Tumor Cells in Bloodstream Using white blood cells to ferry potent cancer-killing proteins through the bloodstream virtually eliminates metastatic prostate cancer in mice, Cornell researchers have confirmed. Why Do Some Infections Persist? In preparing for the possibility of an antibiotic onslaught, some bacterial cultures adopt an all-for-one/one-for-all strategy that would make a socialist proud, University of Vermont researchers have found. Flipping Molecular 'Switch' May Reduce Nicotine's Effects in the Brain Scientists at The Scripps Research Institute (TSRI) have discovered that a lipid (fat molecule) in brain cells may act as a “switch” to increase or decrease the motivation to consume nicotine.TSRI Team Comes Together with Rare Disease Community Don’t worry, science fiction fans, the machines aren’t taking over quite yet. It turns out humans still beat computers at reading and comprehending text.