NanoSight has announced that the Centre for Molecular Nanometrology at the University of Strathclyde has selected an LM-10 characterization system to aid in their research and development of new biosensors.
NanoSight, manufacturers of nanoparticle characterization technology, has announced that the Centre for Molecular Nanometrology at the University of Strathclyde has selected an LM-10 characterization system to aid in their research and development of new biosensors.
Lecturer, Dr Alastair Wark’s research interests are based around the preparation, fictionalization and application of plasmonic nanomaterials. The use of such nanometre-scale materials and tools is opening up exciting new avenues for the investigation of biomolecular interactions and biological systems with sensitivity and accuracy.
Other characterization techniques such as UV-VIS adsorption spectroscopy and DLS (dynamic light scattering) are useful for bulk averaging measurements but it is the ability to visualize individual nanoparticles one at a time that drew former postdoctoral researcher Dr Robert Stokes whilst working with Professor Duncan Graham to select the NanoSight NTA system. This has catalyzed the current research being lead by Dr Wark.
“The NanoSight provides an intuitive way of sensing particles and being able to work dynamically in biocompatible liquids collecting multiple single sets of particle information gives statistical credibility to the data.”
This initial work is leading into developments for biosensors involving the controlled aggregation of functionalized nanomaterials in the presence of a specific target biomolecule. The ability to monitor this process in solution using particle-by-particle measurements cannot be achieved with bulk characterization techniques.
NanoSight’s NTA approach has been shown to be suited to such research activities and with the ability to not only look at spherical particles, but also characterize rod-like materials as well makes the system a powerful nanoscale research and development tool.
Dr Alastair Wark, Lecturer at the University of Strathclyde’s Centre for Molecular Nanometrology and principal user of NanoSight technology for nanoparticle characterization.