Corporate Banner
Satellite Banner
Technology
Networks
Scientific Communities
 
Become a Member | Sign in
Home>News>This Article
  News
Return

The Forschungszentrum Dresden-Rossendorf Chooses NanoSight to Characterize Magnetic Nanoparticles

Published: Wednesday, August 18, 2010
Last Updated: Wednesday, August 18, 2010
Bookmark and Share
NanoSight’s LM-20 nanoparticle characterization system to study magnetic nanoparticles for applications in cancer therapy.

The Institute for Radiopharmacy at the Forschungszentrum Dresden-Rossendorf is using NanoSight’s LM-20 nanoparticle characterization system to study magnetic nanoparticles for applications in cancer therapy.

The research team of Dr Holger Stephan is working to develop magnetic nanoparticles which can be applied in cancer therapy, preferably in combination with intracellular hyperthermia/ablation and endoradionuclide therapies. This requires nanoparticles to be very stable under physiological conditions and they should also avoid accumulation in the reticuloendothelial system.

Many techniques had been used to characterize the nanoparticles before Dr Stephan discovered the NanoSight system. These included Photon Correlation Spectroscopy (PCS), scanning electron microscopy (SEM) and ultra centrifugation. Nanoparticle Tracking Analysis, NTA, has been used to successfully follow the stability of different systems as a function of temperature in EDTA and different cell media.

There are three specific goals for measurement: First is to get information about the size distribution of nanoparticles and, more importantly, their stability under physiological relevant conditions, Next is to study the influence of nanoparticle surface modification on the size distribution finally to achieve structure-activity relationships for the nanoparticles on the cellular uptake behaviour (first step) and cancer tissue accumulation (second step).

Dr Stephan has described several advantages of the NanoSight LM-20 system. He says “the NanoSight provides reliable results on nanoparticles as small as 50nm. Sample handling and measurement is straightforward and experiments are performed more quickly than using PCS. The ability to work directly with relevant solutions removes another block to quickly understanding the behaviour of these magnetic nanoparticles and their ultimate use in treating cancers.”

“Our goal,” continues Dr Stephan “is to rewrite the medical paradigm, currently being “see and treat” and to make the future one of “detect and prevent.” By working on the combining of different therapeutic methodologies, we will provide synergetic medical effectiveness.”


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,900+ scientific posters on ePosters
  • More Than 4,200+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Studying behaviour of Exosomes and Microvesicles using Nanoparticle Tracking Analysis
Dr Gregory Gores of the Mayo Clinic in Rochester, Minnesota is using NTA to study extracellular vesicles.
Tuesday, November 19, 2013
NanoSight Acquired by Malvern Instruments
The acquisition of NanoSight by Malvern Instruments was completed on Friday 27 September.
Monday, September 30, 2013
NanoSight Wins a 2013 Queen's Award for Enterprise – Innovation
Award follows on from their 2012 Queen's Award for Enterprise for International Trade.
Monday, April 22, 2013
Nanoparticle Tracking Analysis Technology Facilitates Cancer Metastasis Research
NanoSight reports on the breakthrough cancer metastasis research of Dr. Hector Peinado Selgas and Dr. David Lyden's research team from Weill Cornell Medical College.
Tuesday, November 13, 2012
Conference Highlights Biomarker Detection Role for NanoSight
Oxford researchers presented new data applying NTA to size and count both cellular microvesicles and exosomes at a low concentration.
Saturday, October 09, 2010
NanoSight Holds First European Users Meeting on Nanoparticle Characterization in Langen, Germany
Meeting provided an excellent opportunity to present new data using nanoparticle tracking analysis, NTA.
Thursday, July 15, 2010
NanoSight holds first European users meeting on nanoparticle characterization in Langen, Germany
NanoSight, world-leading manufacturers of unique nanoparticle characterization technology, together with distributor partners Schaefer Technologie, have recently held a meeting of users of their successful range of nanoparticle tracking analysis instruments in Langen, Germany.
Tuesday, July 13, 2010
University of Leicester Uses NanoSight to Characterize Marine Viruses and Bacteriophages
Microbiologists use NanoSight system to study cyanobacteria and their viruses which involves the accurate enumeration of viral particles.
Wednesday, June 09, 2010
Leiden University uses NanoSight Characterization System to Aid their Drug Delivery Research Programs
NanoSight helps the research group to focus on vaccine delivery and on protein formulation and characterization with respect to immunogenicity.
Wednesday, February 24, 2010
Strathclyde’s Nanometrology Centre Selects NanoSight to Develop New Biosensors
University of Strathclyde has selected an LM-10 characterization system to aid in their research and development of new biosensors.
Wednesday, November 11, 2009
NanoSight to Supply Instrumentation for Wellcome Trust Technology Development Grant
NanoSight’s methodologies aimed at measuring cellular nanoparticles in plasma and urine as biomarkers of a broad range of human disease conditions.
Friday, May 22, 2009
NanoSight Nanoparticle Detection Technique Contributes to Virus Production to Counter MRSA
Researchers at the University of Strathclyde use virus particle detection and counting using Nanoparticle Tracking Analysis to combat MRSA.
Tuesday, December 09, 2008
NanoSight Receives £925,000 in Funding Round to Expand their Nanoparticle Characterization Business
The new round of financing which will enable the company to expand the business with the development of new products and sales channels in the US market.
Thursday, November 06, 2008
Nanosight Angel Investor Round
The angel investor round increases its shareholder base and complements previous investments by Venture Capital companies.
Monday, September 10, 2007
NanoSight Raises £250k in Second Tranche of Fundraising
The investment supports Company’s current sales drive and develops capabilities in nanoparticle analysis.
Wednesday, September 27, 2006
Scientific News
Natural Protein Points to New Inflammation Treatment
Findings may offer insight to effective treatments for inflammatory diseases, such as rheumatoid arthritis, psoriasis, and multiple sclerosis.
Genetic Cause of Rare Allergy
Institute has identified a genetic mutation responsible for a rare form of inherited hives induced by vibratory urticaria.
Battery Component Found to Harm Key Soil Microorganism
The material at the heart of the lithium ion batteries that power electric vehicles, laptop computers and smartphones has been shown to impair a key soil bacterium, according to new research.
Keeping Tumor Growth at Bay
Engineers at Washington University in St. Louis found a way to keep a cancerous tumor from growing by using nanoparticles of the main ingredient in common antacid tablets.
Natural Protein Points to New Inflammation Treatment
Findings may offer insight to effective treatments for inflammatory diseases, such as rheumatoid arthritis, psoriasis, and multiple sclerosis.
Mitochondria Shown to Trigger Cell Ageing
An international team of scientists has for the first time shown that mitochondria, the batteries of the cells, are essential for ageing.
Cancer Cells Kill Off Healthy Neighbours
Cancer cells create space to grow by killing off surrounding healthy cells, according to UK researchers working with fruit flies.
Validating the Accuracy of CRISPR-Cas9
IBS Researchers create multiplex Digenome-seq to find errors in CRISPR-Cas9 processes.
Cancer Drug Target Visualized at Atomic Resolution
New study using cryo-electron microscopy shows how potential drugs could inhibit cancer.
Genetic Mechanism Behind Cancer-Causing Mutations
Researchers at Indiana University has identified a genetic mechanism that is likely to drive mutations that can lead to cancer.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,900+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,200+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!