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FDA Chooses Award Winning Ion Chromatography System from Dionex for Analysis of Biogenic Amines

Published: Tuesday, November 16, 2010
Last Updated: Tuesday, November 16, 2010
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Dionex is pleased to announce that the United States Food and Drug Administration (FDA) in Irvine, California have purchased the new, award-wining Dionex ICS-5000 (analytical and capillary scale) with Mass Spectrometry system for the analysis of biogenic amines (histamine, putrescine, and cadaverine) in fish samples.

Consumption of large amounts of biogenic amines can lead to allergic reactions in some individuals, and can also be life threatening in some cases. The most well known intoxications of biogenic amines are scombroid poisoning and the cheese reaction, which occur from consuming food products containing high concentrations of histamine or tyramine, respectively.

The U.S. FDA has established a defect action level of 50 mg/kg histamine and a toxicity level of 500 mg/kg histamine in fish. The ICS-5000 system is ideal for IC-MS analysis and applications such as measuring histamine levels to the highest level of sensitivity. In addition, the system flexibility and modularity provides the ability to analyze samples at capillary, microbore, or standard flow rates (or any combination of two in a dual system), and configure an ion chromatography system specifically for the solutions you need.

Dionex has also developed a number of applications for determining biogenic amines in meat and fish (AN 183: Determination of Biogenic Amines in Fermented and Non-Fermented Foods), alcoholic beverages (AN 182: Determination of Biogenic Amines in Alcoholic Beverages), and fruit, vegetables, and chocolate (AU 162: Determination of Biogenic Amines in Fruit, Vegetables, and Chocolate).


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