Corporate Banner
Satellite Banner
Scientific Communities
Become a Member | Sign in
Home>News>This Article

Selcia and NeuroVive to Develop New Mitochondrial Medicines

Published: Monday, October 10, 2011
Last Updated: Monday, October 10, 2011
Bookmark and Share
Selcia Limited and NeuroVive Pharmaceutical AB have signed a research collaboration agreement to develop new medicines and drug compounds targeting mitochondrial physiology and pathophysiology.

The collaboration is focused on mitochondrial medicine, an emerging therapeutic modality that promises innovative new treatments for major chronic diseases, such as cancer and obesity, and acute conditions such as stroke and heart failure.

Selcia and NeuroVive will jointly invest in the collaboration to combine Selcia´s leading expertise in medicinal and analytical chemistry, with NeuroVive´s advanced research and development programs in mitochondrial medicine.

Mitochondria are well known as the energy-producing powerhouses of all cells and are critical for optimal cellular function and survival, as well as initiating cell death. Research has implicated mitochondrial dysfunction in acute conditions: such as stroke and heart failure; chronic diseases like diabetes; within neurodegeneration, such as Alzheimer´s disease; and in the ageing process. Impaired cellular energy levels is a primary result of mitochondrial dysfunction, which has a number of causes ranging from free radical damage to genetic mutations. Mitochondrial medicines seek to optimise cellular energy levels and health through protecting or enhancing mitochondrial function.

Simon Saxby, CEO of Selcia, commented on the collaboration; “We are delighted to be collaborating with NeuroVive in the area of mitochondrial medicine. Our combined resources have the potential to yield a number of new drugs and supplements that could revolutionise the treatment of diseases caused by mitochondrial dysfunction, as well as recovery regimens for a number of patient populations”.

Mikael Brönnegård, CEO of NeuroVive Pharmaceutical, said, “In this collaboration with Selcia, NeuroVive will target the development of new drugs that are at the cutting edge for diseases like stroke, heart attack, obesity, and cancer – all large potential markets with significant burden of disease. This will add new drug entities to NeuroVive's broad development pipeline and will enable the company to capitalise on the commercial opportunities deriving from our leading expertise in mitochondrial research, including our cyclophilin-D program”.

NeuroVive´s CSO Eskil Elmér, added: “Mitochondrial medicine deals with conditions that are related to mitochondrial dysfunction (i.e., reduced or limited energy production) due to a number of causes ranging from specific genetic mutations to disease-related secondary mitochondrial damage. It also applies to situations requiring an increased energy demand, such as recovering from extensive surgery and intensive care and situations in which augmented energy expenditure (e.g., obesity) is important. This collaboration with Selcia will allow us to accelerate the discovery and development of new mitochondrial medicines and drug-like compounds within the scope of our current R&D budget in the discovery phase”.

Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,800+ scientific posters on ePosters
  • More Than 4,000+ scientific videos on LabTube
  • 35 community eNewsletters

Sign In

Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Selcia and Cantab Announce Drug Discovery Collaboration
Partnership to accelerate Cantab’s programme to develop improved antibiotics for multidrug resistant Gram-negative bacterial infections.
Thursday, September 05, 2013
Selcia Introduces New Prolyl Isomerase Screening Service
Selcia Limited has announced the launch of a new platform to enable drug discovery and development on the target family of peptidyl-prolyl cis-trans isomerases (“PPIases”).
Friday, February 01, 2013
Selcia and ExonHit Therapeutics Announce Successful Fragment Screening Collaboration
Successful completion of a drug discovery project with ExonHit Therapeutics using Selcia’s fragment screening technology.
Thursday, April 21, 2011
Selcia Appoints Simon Saxby as CEO and Andreas Rummelt to its Board
Simon Saxby brings successful leadership and executive management experience to the role of Selcia’s CEO and Andreas is recognized as a global expert in drug development and will further enhance the strategic strength of Selcia’s Board.
Thursday, February 24, 2011
Selcia and Gilead Sciences Extend Liver Disease Drug Discovery Collaboration
Selcia Limited announced a drug discovery collaboration agreement with Gilead Sciences Inc. Selcia’s chemists and biologists will continue to provide integrated drug discovery services to support Gilead’s liver disease research programmes.
Tuesday, November 30, 2010
Convergence Pharmaceuticals and Selcia Announce Drug Discovery Collaboration Around Chronic Pain
Convergence Pharmaceuticals Limited, the new company focused on the development of novel and high value analgesic medicines, and Selcia Limited, a contract research organisation, today are pleased to announce that they have entered into a drug discovery collaboration to identify and develop high quality candidate molecules for the treatment of chronic pain.
Thursday, November 25, 2010
Simon Saxby Joins Board at Selcia
Selcia Limited, a leading provider of contract research services in 14-C custom radiolabelling, integrated drug discovery, fragment screening and medicinal chemistry today announced the high profile appointment of Simon Saxby to the Board as a non-executive director.
Monday, June 28, 2010
Scientific News
High Throughput Mass Spectrometry-Based Screening Assay Trends
Dr John Comley provides an insight into HT MS-based screening with a focus on future user requirements and preferences.
The MaxSignal Colistin ELISA Test Kit from Bioo Scientific
Kit can help prevent the antibiotic apocalypse by keeping last resort drugs out of the food supply.
"Good" Mozzie Virus Might Hold Key to Fighting Human Disease
Australian scientists have discovered a new virus carried by one of the country’s most common pest mosquitoes.
Non-Disease Proteins Kill Brain Cells
Scientists at the forefront of cutting-edge research into neurodegenerative diseases such as Alzheimer’s and Parkinson’s have shown that the mere presence of protein aggregates may be as important as their form and identity in inducing cell death in brain tissue.
Closing the Loop on an HIV Escape Mechanism
Research team finds that protein motions regulate virus infectivity.
New Class of RNA Tumor Suppressors Identified
Two short, “housekeeping” RNA molecules block cancer growth by binding to an important cancer-associated protein called KRAS. More than a quarter of all human cancers are missing these RNAs.
Potential Treatment for Life-Threatening Viral Infections Revealed
The findings point to new therapies for Dengue, West Nile and Ebola.
World’s First Therapeutic Venom Database
Open-source library describes nearly 43,000 effects on the human body.
Biologists Induce Flatworms to Grow Heads and Brains of Other Species
Findings shed light on role of a new kind of epigenetic signaling in evolution, could yield clues for understanding birth defects and regeneration.
Fat Cells Originating from Bone Marrow Found in Humans
Cells could contribute to diabetes, heart disease.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,800+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,000+ scientific videos