Corporate Banner
Satellite Banner
Technology
Networks
Scientific Communities
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Integromics Partners with FPGMX to Develop Low-Cost Methods for Clinical Genomics

Published: Tuesday, February 07, 2012
Last Updated: Tuesday, February 07, 2012
Bookmark and Share
Venture attracts EUR one million grant for ‘new frontier’ of data interpretation for medical usage.

Integromics® has announced that it has entered into a partnership with Professor Carracedo and his team at the Galician Foundation of Genomic Medicine (FPGMX), a recipient of the European Life Technologies ‘Ion Torrent Visionary Winners Award’, for the development of inexpensive solutions for clinical genomics.

Based on the strength of its R&D work, the new partnership has been awarded a EUR one million grant from the European Regional Development Fund and the Spanish Government for a project entitled ‘Advanced analysis and interpretation of Low-cost next generation sequencing data for clinical applications (ApliClinics LC-NGS).

The interpretation of next generation sequencing (NGS) data has been recognized as a major bottleneck in the adoption of personalized medicine, both in terms of cost and time.

The ApliClinics collaboration has been designed to address the issues, at the bench and bioinformatics levels, being faced by the clinical labs trying to apply NGS technology.

The project aims to improve procedures and optimize tools to make the use of NGS faster in the routine healthcare environment, which will alleviate the current lack of applications critically needed by clinicians, as well as helping to lessen their workload.

The ApliClinics project opens a new field of application for Integromics and represents an ideal opportunity for the company to reinforce its commitment to the development of software solutions for personalized medicine.

“This will be the first time that Integromics will be working side-by-side with clinicians to bridge the gap between our NGS technology and how it translates into healthcare for patients,” said Eduardo González Couto, chief strategy officer, Integromics.

Couto continued, “The synergy of the clinical genomic pioneers from the FPGMX and the expertise of the bioinformaticians we have at Integromics will undoubtedly help to accelerate the development of solutions for clinical genomics.

“Automated next-gen sequencers have increased the speed and reduced the cost of sequencing, making it possible to offer genetic testing to consumers. Producing the genomic data is no longer a problem, however, it is the analysis and interpretation of the data which has become the ‘new frontier’. In order to characterize and interpret the data for medical usage, novel bioinformatics tools are crucially needed.”

As Kevin Davies discussed in his essay ‘The $100,000 Genome Interpretation’, as the cost of sequencing continues to freefall it has become cheaper and faster for clinical genome labs to sequence a full exome of a patient instead of a panel of individual genes.

However, there are neither enough bioinformaticians nor enough prepared healthcare professionals to analyze the large sets of genes in a genome or exome.

Even the professionals that can interpret genomic data would require weeks or months to analyze the data of one patient. In one of the most comprehensive clinical genome analysis (reported by Ashley et al., Lancet 2010; 375; 1525-35) the task of interpreting one genome involved more than 20 collaborators.

"The interest of the group, in addition to genomic research, is the practical translation of next generation sequencing to clinical routine casework,” said Prof. Angel Carracedo, director of the FPGMX.

Prof. Carracedo continued, “For this reason this project is essential for us. In this moment the bottleneck is not data production but to have bioinformatic tools allowing us to obtain reliable and accurate information of the variation found after DNA sequencing using NGS facilities, which is the main objective of this project."

Against this setting, and as NGS develops for specific cases in a broader clinical setting, it is hoped that the findings of the ApliClinics project, in terms of software and lab procedures, will bring low cost NGS technology closer to a clinical reality.

Integromics will be looking to announce the first results of the ApliClinics project in Q4 2012.


Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,400+ scientific posters on ePosters
  • More Than 3,700+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Integromics Partners with CITRE and CEIT
Venture attracts EUR 2 million grant for ‘new frontier’ of data interpretation for drug development.
Friday, April 19, 2013
Integromics Invests in the Optimization of Computing Performance for Bioinformatics Applications
Key collaboration with European experts of HPC to bring new big-data computing solutions into genomics.
Friday, March 22, 2013
Integromics and Ingenuity Expand their Co-operation with the Integration of a Fourth Integromics Product to Ingenuity’s IPA
Combined solutions to offer bridge between discovery and relevance of genomics and proteomics.
Thursday, April 07, 2011
Novel Polyadenylation Genome-wide Profiling Achieved using Next Generation Sequencing Software
A paper published in the journal Cell highlighting a novel genome wide profile of polyadenylation events in human and yeast, performed with Direct RNA Sequencing, demonstrated the importance of appropriate bioinformatics software in maximizing the value of the genomic data.
Monday, January 10, 2011
Integromics and TATAA Biocenter Collaborate to offer Comprehensive qPCR Data Analysis
The TATAA Biocenter is recommending Integromics’ RealTime StatMiner® as a complete solution for qPCR data analysis.
Monday, March 08, 2010
Integromics S.L. Integrates GeneBio’s Phenyx within OmicsHub Proteomics
Geneva Bioinformatics (GeneBio) SA and Integromics S.L. today announced that GeneBio's Phenyx software platform for MS data analysis has been successfully integrated into Integromics’ latest proteomics data analysis and management tool - OmicsHub Proteomics. This integration gives Phenyx and OmicsHub Proteomics users the possibility of combining results from different search engines thereby increasing the accuracy of the protein identification process.
Wednesday, September 23, 2009
Scientific News
RNAi Screening Trends
Understand current trends and learn which application areas are expected to gain in popularity over the next few years.
New Weapon in the Fight Against Blood Cancer
This strategy, which uses patients’ own immune cells, genetically engineered to target tumors, has shown significant success against multiple myeloma, a cancer of the plasma cells that is largely incurable.
TOPLESS Plants Provide Clues to Human Molecular Interactions
Scientists at Van Andel Research Institute have revealed an important molecular mechanism in plants that has significant similarities to certain signaling mechanisms in humans, which are closely linked to early embryonic development and to diseases such as cancer.
Toxin from Salmonid Fish has Potential to Treat Cancer
Researchers from the University of Freiburg decode molecular mechanism of fish pathogen.
Study Finds Non-Genetic Cancer Mechanism
Cancer can be caused solely by protein imbalances within cells, a study of ovarian cancer has found.
Scientists Create CRISPR/Cas9 Knock-In Mutations in Human T Cells
In a project spearheaded by investigators at UC San Francisco, scientists have devised a new strategy to precisely modify human T cells using the genome-editing system known as CRISPR/Cas9.
Researchers Find U.S. Breast Milk is Glyphosate Free
Washington State University scientists have found that glyphosate, the main ingredient in the herbicide Roundup, does not accumulate in mother’s breast milk.
Peering into the Vapors
Research suggests that e-cigarettes are much less harmful than previous studies have indicated.
New Technique for Mining Health-conferring Soy Compounds
A new procedure devised by U.S. Department of Agriculture (USDA) scientists to extract lunasin from soybean seeds could expedite further studies of this peptide for its cancer-fighting potential and other health benefits.
Long-sought Discovery Fills in Missing Details of Cell 'Switchboard'
A biomedical breakthrough reveals never-before-seen details of the human body’s cellular switchboard that regulates sensory and hormonal responses.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,400+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
3,700+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FREE!