Corporate Banner
Satellite Banner
Scientific Communities
Become a Member | Sign in
Home>News>This Article

Reinnervate and Roslin Cellab Announce Plans to Collaborate

Published: Friday, April 27, 2012
Last Updated: Friday, April 27, 2012
Bookmark and Share
Collaboration on the development of protocols for three dimensional growth of hESC’s using Alvetex®Scaffold.

Reinnervate Ltd and Roslin Cellab has announced that they will join forces to develop protocols for the three dimensional growth of human Embryonic Stem Cells (hESCs).

‘This is a great opportunity for two innovative UK companies to combine their expertise and knowledge to produce exciting new tools for stem cell biologists’ said Richard Rowling - Commercial Director at Reinnervate Ltd.

‘We are delighted that Roslin Cellab has agreed to work with us on this project. They bring a wealth of experience and expert knowledge in the development and delivery of custom tools and protocols in the field of hESC biology. Their professional approach and attention to detail is just what we were looking for’ he added.

Prof Stefan Przyborski, CSO and founder of Reinnervate Ltd, commented: ‘It is well known that the physical environment in which cells grow plays an important role in controlling cell differentiation and the development of functioning tissues. Current two dimensional (2D) models restrict the growth potential of differentiating stem cells. The culture of cells in three dimensions (3D) radically enhances cell growth, differentiation and function. At Reinnervate, we have developed Alvetex®Scaffold which provides a solution for simple and routine 3D cell culture. In this collaboration, we are combining the advantages of 3D cell growth with the enormous potential of hESCs. Preliminary work has already demonstrated enhanced neural development by stem cells using Alvetex®Scaffold technology. We are now engaged in more extensive investigations to fully exploit 3D cell differentiation by hESCs in collaboration with Roslin Cell Lab.’

Jason King, Manager of Business Development at Roslin Cellab said ‘we are seeing great demand for improved 3D culture systems. Stem cell scientists can use these to study the biology of the stem cell “niche”. This is the 3D microenvironment in which stem cells normally reside until they receive signals that cause them to start dividing and to move out into the organ to differentiate into cells of the required type (eg. heart, brain or liver cells) and repair tissue damage. As a company we have a strong interest in liver cells (hepatocytes) which we can make from our stem cell lines. It is known that when hepatocytes are grown in 3D structures, they have both better metabolic enzyme activity and extended life spans, which are both great advantages when using these cells in cell-based toxicity assays.’

As part of the collaboration, Reinnervate will supply its market leading Alvetex®Scaffold technology and general expertise in the 3D growth of cells in vitro. Roslin Cellab will supply cells, expertise and protocol development capabilities to the project.

The two companies will also investigate the growth of hESC’s on new alvetex® product formats that may offer the ability to improve and simplify embryoid body assay protocols.

Embryoid bodies are derived from stem cells and consist of a broad array of differentiated tissues.

In many respects they resemble the structures that form in teratoma tumours when stem cells are transplanted into an animal host. An aspect of this collaboration will include using alvetex technology to support the growth of embryoid body-like structures.

This will subsequently be developed into a robust procedure to reduce the need to use animals for producing teratomas as a test of stem cell developmental potential.

Financial terms were not disclosed.

Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,600+ scientific posters on ePosters
  • More Than 3,800+ scientific videos on LabTube
  • 35 community eNewsletters

Sign In

Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Reinnervate Partners with Oncotest and SBH Sciences
Companies to partner on introductory services for screening novel anti-cancer drugs using 3D tumour cell culture.
Thursday, October 31, 2013
Reinnervate Ltd and Roslin Cellab Partner
Reinnervate Ltd announced that it is entering into a collaboration with Roslin Cellab to develop 3D stem cell printing products and services using Alvetex® technology.
Friday, September 20, 2013
3D cell Culture Firm Reinnervate and Specialist Oncology CRO Oncotest GmbH Enter Collaboration Agreement
Oncotest to offer enhanced pre-clinical oncology and cancer research screening services incorporating Alvetex®Scaffold 3D cell culture technology.
Monday, January 07, 2013
Reinnervate and Tecan Sign Co-marketing Agreement
Both Companies to develop automated 3D cell culture solutions for improved cellular assays.
Tuesday, November 27, 2012
Reinnervate and Kirkstall to Collaborate on New 3D Cell Culture Products
Companies will collaborate to bring next generation three dimensional (3D) cell culture products to market in 2012. The two UK companies develop cell culture systems that bridge the current gap between 2D in-vitro cell culture and animal models.
Monday, March 19, 2012
New Reinnervate Whitepaper Includes Details on Live 3D Cell Imaging in 3D Cell Culture Using Alvetex®
The release is set to help scientists make the switch from traditional 2D cell culture to 3D cell growth.
Monday, January 30, 2012
Reinnervate and Mirus Bio announce collaboration
Reinnervate and Mirus Bio announce commercial agreement to launch new range of products for the transfection of cells cultured in 3D.
Friday, November 18, 2011
Alvetex® Voted One of Most Technologically Significant New Research Products By R&D Magazine
Alvetex® enables genuine 3D cell growth to be performed routinely and cost effectively in cell biology laboratories.
Monday, June 27, 2011
Reinnervate Partners with AMS Biotechnology (Europe) Limited for Distribution of Alvetex®
Alvetex® is a unique and proprietary cell culture scaffold that enables genuine 3D cell growth to be performed routinely and cost-effectively in cell biology laboratories.
Wednesday, June 01, 2011
Reinnervate Enhances Commercial and Product Development Teams with Key Senior Appointments
Appointments of Richard Rowling as commercial director and Barry Lynch as marketing manager to lead the sales and marketing operations supporting alvetex®.
Wednesday, April 06, 2011
Alvetex® Named in the “Top Ten Life Science Innovations of 2010” by The Scientist Magazine
Reinnervate’s 3D cell culture technology selected as one the ten most exciting new tools to hit the life sciences market this year.
Monday, December 06, 2010
Reinnervate Partners with LGC for Global Distribution of Alvetex®
Additional collaboration to develop 3d cell cultures for applications in drug discovery and development.
Tuesday, November 30, 2010
Reinnervate Partners with LGC for Global Distribution of ALVETEX®
Additional collaboration to develop 3D cell cultures for applications in drug discovery and development.
Monday, November 29, 2010
Reinnervate Completes Expansion into New Purpose-Built Facility at Netpark
Reinnervate, a life sciences company driving the adoption of routine 3D cell culture, has announced its expansion into a new purpose-built research and production facility at NETPark near Sedgefield, UK.
Tuesday, November 16, 2010
Reinnervate Launches new Website with Interactive Technical Resource for Routine 3D Cell Culture
New site provides scientific and technical information on 3D cell culture based on Reinnervate’s core Alvetex® technology.
Wednesday, October 13, 2010
Scientific News
Fixing Holes in the Heart Without Invasive Surgery
UV-light enabled catheter is a medical device which represents a major shift in how cardiac defects are repaired.
Chromosomal Chaos
Penn study forms basis for future precision medicine approaches for Sezary syndrome
Enzyme Malfunction May be Why Binge Drinking Can Lead to Alcoholism
A new study in mice shows that restoring the synthesis of a key brain chemical tied to inhibiting addictive behavior may help prevent alcohol cravings following binge drinking.
Key to Natural Detoxifier’s Reactivity Discovered
Results have implications for health, drug design and chemical synthesis.
New Treatment for Obesity Developed
Researchers at the University of Liverpool, working with a global healthcare company, have helped develop a new treatment for obesity.
New Protein Found in Immune Cells
Immunobiologists from the University of Freiburg discover Kidins220/ARMS in B cells and demonstrate its functions.
Will Brain Palpation Soon Be Possible?
Researchers have developed non-invasive brain imaging technique which provides the same information as physical palpation.
Shaking Up the Foundations of Epigenetics
Researchers at the Centre for Genomic Regulation (CRG) and the University of Barcelona (UB) published a study that challenges some of the current beliefs about epigenetics.
Groundbreaking Computer Program Diagnoses Cancer in Two Days
Researchers have combined genetics with computer science and created a new diagnostic technology can with 85 per cent certainty identify the source of the disease and thus target treatment and, ultimately, improve the prognosis for the patient.
Michigan Researchers Use Raman Spectroscopy
inVia confocal Raman microscope used in the study of various childhood diseases.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,600+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
3,800+ scientific videos