Satellite Banner
Technology
Networks
Scientific Communities
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Scripps Research Appoints Cancer Biologist

Published: Monday, August 06, 2012
Last Updated: Monday, August 06, 2012
Bookmark and Share
Christoph Rader is appointed as associate professor in the Department of Cancer Biology and the Department of Molecular Therapeutics.

Before coming to Scripps Florida, Rader was a senior scientist at the National Cancer Institute (NCI) in Bethesda, Maryland. Prior to that, he was an assistant professor on the La Jolla, California, campus of Scripps Research.

“We want to welcome Christoph back to Scripps Research,” said John L. Cleveland, chair of the Scripps Research Department of Cancer Biology. “In California, his groundbreaking antibody research helped pioneer a hybrid cancer therapy, and at NIH he was responsible for developing several innovative approaches to antibody drug and target discovery. He’s a great addition to our department and to the institute as a whole.”

“It’s a great pleasure to return to Scripps Research—and to be part of Scripps Florida,” said Rader, 46, who lives with his wife and two sons in Jupiter. “The faculty here is terrific, not only in cancer biology, but also in molecular therapeutics and chemistry. What I missed most at the NCI was being able to work more closely with chemists—they were 45 minutes away. Now, chemists are minutes from my office.”

Rader has already taken advantage of that proximity, launching collaborations with Scripps Florida chemists William R. Roush and Thomas Kodadek.

Rader’s research is focused on developing antibody therapies to treat cancer. “Monoclonal antibody therapy of cancer is a tremendously exciting and rewarding field that thrives on multidisciplinary expertise in biology, biochemistry, chemistry, pharmacology, and medicine,” said Rader. “Prompted by current knowledge, we have gone back to the drawing board to design, engineer, test, and deliver the next generation of monoclonal antibodies that target cancer cells with even higher precision and potency. Scripps Florida is an ideal place for hanging our drawing board and developing novel technologies at the interface of chemistry and biology.”

Rader studied biochemistry and molecular biology at the University of Bayreuth in Germany (1986-1988) and at the University of Zurich in Switzerland (1988-1995), where he graduated with a diploma in biochemistry in 1991. In 1995, he was awarded a PhD with honors from the University of Zurich for his work on immunoglobulin superfamily molecules.

Rader did postdoctoral work with Professor Carlos F. Barbas III at Scripps California, where he specialized in antibody engineering, phage display, and catalytic antibody technologies. Following his promotion to assistant professor at Scripps Research in 1999, he won the prestigious Investigator Award from the Cancer Research Institute in 2000. Shortly after, he was part of a Scripps Research team that invented the concept of chemical programming of monoclonal antibodies to generate hybrid cancer therapeutics, a cross between traditional small molecules and a certain type of monoclonal antibody. After commercialization, this innovation has brought several new drugs into phase I and II clinical trials for the treatment of various cancers and metabolic diseases.

Rader joined the NCI in 2003 to head the Antibody Technology Section in the Experimental

Transplantation and Immunology Branch. In 2007, he received the NCI Director's Intramural Innovation Award for Principal Investigators for a novel chemical programming concept. His achievements include more than 80 publications and 13 patents or patent applications in the area of antibody engineering and conjugation technologies.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,200+ scientific posters on ePosters
  • More Than 4,700+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

New Method Opens Door to Development of Many New Medicines
Findings from TSRI reveal human proteins are better drug targets than previously thought.
Friday, June 17, 2016
Harnessing Nature’s Vast Array of Venoms for Drug Discovery
Scripps scientists have developed a method for rapidly identifying venoms.
Wednesday, May 25, 2016
Breakthrough Approach to Breast Cancer Treatment
Scripps scientists have designed a drug candidate that decreases growth of breast cancer cells.
Tuesday, May 24, 2016
Making Genetic Data Easier to Search
Scripps team streamlines biomedical research by making genetic data easier to search.
Tuesday, May 17, 2016
Potent Therapeutic 'Warheads' That Target Cancer Cells
Scripps scientists have developed molecular “warheads” that could be used to treat cancer.
Tuesday, May 17, 2016
Predicting Cell Changes that Affect Breast Cancer Growth
Researchers find small structural changes in a key breast cancer receptor that can predict cancer growth.
Tuesday, May 03, 2016
Secrets of a Deadly Virus Family Revealed
Scripps Research scientists uncover the glycoprotein structure of LCMV. The findings could guide development of treatments for Lassa fever.
Wednesday, April 27, 2016
First ‘Teenage’ HIV-Neutralizing Antibody Discovered
Scientists have studied the evolution of anti-HIV antibodies, with hopes of creating a vaccine to prevent AIDS.
Wednesday, April 06, 2016
Discovering 'Outlier' Enzymes
Researchers at TSRI and Salk Institute have discovered 'Outlier' enzymes that could offer new targets to treat type 2 diabetes and inflammatory disorders.
Saturday, April 02, 2016
Encouraging Foundation for Upcoming AIDS Vaccine Clinical Trial
Engineered vaccine protein binds key immune cells that exist in nearly everyone.
Tuesday, March 29, 2016
New Approach to Curbing Cancer Cell Growth
Using a new approach, scientists at The Scripps Research Institute (TSRI) and collaborating institutions have discovered a novel drug candidate that could be used to treat certain types of breast cancer, lung cancer and melanoma.
Monday, March 14, 2016
Vaccine Against Dangerous Designer Opioids
With use of synthetic opioid "designer drugs" on the rise, scientists from The Scripps Research Institute (TSRI) have a new strategy to curb addiction and even prevent fatal overdoses.
Thursday, February 18, 2016
Potential Target for Treatment of Autism
Grant of $2.4 million will support further research.
Friday, October 02, 2015
Key Morphine Regulator Identified
The findings could lead to less addictive pain medications.
Thursday, September 24, 2015
$6 Million Awarded to Develop Alternative HIV/AIDS Vaccine
Scientists from the Florida campus of The Scripps Research Institute (TSRI) have been awarded up to nearly $6 million from the Bill & Melinda Gates Foundation to develop a revolutionary HIV/AIDS alternative vaccine that has demonstrated great potential in animal models.
Thursday, September 24, 2015
Scientific News
ASMS 2016: Targeting Mass Spectrometry Tools for the Masses
The expanding application range of MS in life sciences, food, energy, and health sciences research was highlighted at this year's ASMS meeting in San Antonio, Texas.
Benchtop Automation Trends
Gain a better understanding of current interest in and future deployment of benchtop automated systems.
Some Women With PCOS May Have Adrenal Disorder
Researchers at NIH have found that a subgroup of women with PCOS, a leading cause of infertility, may produce excess adrenal hormones.
Alzheimer's Genetics Point To New Research Direction
A University of Adelaide analysis of genetic mutations which cause early-onset Alzheimer’s disease suggests a new focus for research into the causes of the disease.
Penn State, TB Alliance, and GSK Partner To Discover New Treatments For TB
A new collaboration between TB Alliance, GSK, and scientists in the Eberly College of Science seeks to find new small molecules that can be used to create antibiotics in the fight against tuberculosis (TB).
Manufactured Stem Cells To Advance Clinical Research
Clinical-grade cell line will enable development of new therapies and accelerate early-stage clinical research.
Faster Detection of Pathogens in the Lungs
Thanks to new molecular-based methods, mycobacterial pathogens that cause pulmonary infections or tuberculosis can now be detected much more quickly.
Contagious Cancers Are Spreading in Shellfish
Direct transmission of cancer among some marine animals may be more common than once thought, suggests a new study published in Nature by researchers at Columbia University Medical Center (CUMC).
Contagious Cancers Are Spreading in Shellfish
Direct transmission of cancer among some marine animals may be more common than once thought, suggests a new study published in Nature by researchers at Columbia University Medical Center (CUMC).
Anthrax Vaccine Protects Monkeys
Vaccination with the anthrax capsule—a naturally occurring component of the bacterium that causes the disease—completely protected monkeys from lethal anthrax infection, according to a recently published study.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,200+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,700+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!