Corporate Banner
Satellite Banner
Technology
Networks
Scientific Communities
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Scripps Research Appoints Cancer Biologist

Published: Monday, August 06, 2012
Last Updated: Monday, August 06, 2012
Bookmark and Share
Christoph Rader is appointed as associate professor in the Department of Cancer Biology and the Department of Molecular Therapeutics.

Before coming to Scripps Florida, Rader was a senior scientist at the National Cancer Institute (NCI) in Bethesda, Maryland. Prior to that, he was an assistant professor on the La Jolla, California, campus of Scripps Research.

“We want to welcome Christoph back to Scripps Research,” said John L. Cleveland, chair of the Scripps Research Department of Cancer Biology. “In California, his groundbreaking antibody research helped pioneer a hybrid cancer therapy, and at NIH he was responsible for developing several innovative approaches to antibody drug and target discovery. He’s a great addition to our department and to the institute as a whole.”

“It’s a great pleasure to return to Scripps Research—and to be part of Scripps Florida,” said Rader, 46, who lives with his wife and two sons in Jupiter. “The faculty here is terrific, not only in cancer biology, but also in molecular therapeutics and chemistry. What I missed most at the NCI was being able to work more closely with chemists—they were 45 minutes away. Now, chemists are minutes from my office.”

Rader has already taken advantage of that proximity, launching collaborations with Scripps Florida chemists William R. Roush and Thomas Kodadek.

Rader’s research is focused on developing antibody therapies to treat cancer. “Monoclonal antibody therapy of cancer is a tremendously exciting and rewarding field that thrives on multidisciplinary expertise in biology, biochemistry, chemistry, pharmacology, and medicine,” said Rader. “Prompted by current knowledge, we have gone back to the drawing board to design, engineer, test, and deliver the next generation of monoclonal antibodies that target cancer cells with even higher precision and potency. Scripps Florida is an ideal place for hanging our drawing board and developing novel technologies at the interface of chemistry and biology.”

Rader studied biochemistry and molecular biology at the University of Bayreuth in Germany (1986-1988) and at the University of Zurich in Switzerland (1988-1995), where he graduated with a diploma in biochemistry in 1991. In 1995, he was awarded a PhD with honors from the University of Zurich for his work on immunoglobulin superfamily molecules.

Rader did postdoctoral work with Professor Carlos F. Barbas III at Scripps California, where he specialized in antibody engineering, phage display, and catalytic antibody technologies. Following his promotion to assistant professor at Scripps Research in 1999, he won the prestigious Investigator Award from the Cancer Research Institute in 2000. Shortly after, he was part of a Scripps Research team that invented the concept of chemical programming of monoclonal antibodies to generate hybrid cancer therapeutics, a cross between traditional small molecules and a certain type of monoclonal antibody. After commercialization, this innovation has brought several new drugs into phase I and II clinical trials for the treatment of various cancers and metabolic diseases.

Rader joined the NCI in 2003 to head the Antibody Technology Section in the Experimental

Transplantation and Immunology Branch. In 2007, he received the NCI Director's Intramural Innovation Award for Principal Investigators for a novel chemical programming concept. His achievements include more than 80 publications and 13 patents or patent applications in the area of antibody engineering and conjugation technologies.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,300+ scientific posters on ePosters
  • More Than 5,000+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

'Missing Evolutionary Link' of Natural Drug Source Found
Scripps Florida study finds 'missing evolutionary link' of a widely used natural drug source
Monday, August 22, 2016
4 Billion-Year-Old RNA Synthesized
TSRI are one step closer to the lab recreation of the "RNA world" of 4 billion years ago.
Wednesday, August 17, 2016
Surprising Twist in Immune Biology
TSRI researchers have found the ‘lead actors’ in immune cell development, shedding light on casues of autoimmune disease.
Wednesday, August 03, 2016
Influencing the Immune System
A TSRI study has opened the door to influencing the immune system, yielding possible boosts to vaccine efficiency and immunology.
Tuesday, August 02, 2016
Drug Candidates Reduce Abnormal Protein Production
New drug candidates improve cell ability to catch miss-folded proteins that could cause deadly diseases.
Friday, July 22, 2016
Scientists Link Bipolar Disorder to Unexpected Brain Region
Researchers from The Scripps Research Institute have found that gene within the brain’s striatum could be linked to biopolar disorder.
Wednesday, July 20, 2016
New Cancer Drug Target Found in Dual-Function Protein
Findings from a study from TSRI have shown that targeting a protein called GlyRS might help to halt cancer growth.
Wednesday, June 29, 2016
HIV Structure Stabilized
Findings represent ‘big accomplishment’ in biomedical engineering and design.
Wednesday, June 29, 2016
New Method Opens Door to Development of Many New Medicines
Findings from TSRI reveal human proteins are better drug targets than previously thought.
Friday, June 17, 2016
Harnessing Nature’s Vast Array of Venoms for Drug Discovery
Scripps scientists have developed a method for rapidly identifying venoms.
Wednesday, May 25, 2016
Breakthrough Approach to Breast Cancer Treatment
Scripps scientists have designed a drug candidate that decreases growth of breast cancer cells.
Tuesday, May 24, 2016
Making Genetic Data Easier to Search
Scripps team streamlines biomedical research by making genetic data easier to search.
Tuesday, May 17, 2016
Potent Therapeutic 'Warheads' That Target Cancer Cells
Scripps scientists have developed molecular “warheads” that could be used to treat cancer.
Tuesday, May 17, 2016
Predicting Cell Changes that Affect Breast Cancer Growth
Researchers find small structural changes in a key breast cancer receptor that can predict cancer growth.
Tuesday, May 03, 2016
Secrets of a Deadly Virus Family Revealed
Scripps Research scientists uncover the glycoprotein structure of LCMV. The findings could guide development of treatments for Lassa fever.
Wednesday, April 27, 2016
Scientific News
Shedding Light on HIV Vaccine Design
Broadly speaking - Mathematical modelling of host-pathogen coevolution sheds light on HIV vaccine design.
AACC 2016 Sees Clinical Chemistry Labs Drive Precision Medicine Offerings
Biomarker assays to enable precision medicine and risk assessment, mass spec-based tests designed for use in clinical labs large and small, and liquid biopsy technology captured the spotlight at the AACC annual meeting.
Automated Patch Clamping Trends
Learn more about current practices, preferences and metrics in ion channel drug screening using APC technology.
Microbial Analysis of MilkTrucks
A microbial study of milk trucks aims to improve dairy food safety and quality.
New Method of Cancer Immunotherapy
Stanford chemists have dicovered a new form of cancer immunotherapy using sugar presence manipulation.
Unravelling the Metastatic Mechanism of Melanoma
Research has uncovered the mechanism of melanoma spreading; the findings could lead to a cure for the disease.
Diagnosing Bacterial Infections in Blood Samples
Researchers have diagnosed a bacterial infection from a blood sample in infants.
Gene Therapy Via Ultrasound
Research into a gene therapy approach called sonoporation could help combat heart disease and cancer.
Creating Embryos with 'Heteroplasmy'
New discovery in genetic research could lead to treatments for mitochondrial diseases.
Molecular Alarm Clock Wakes Resting Ovules
Study of fruit flies yields discovery of a molecular "alarm clock" that activates resting ovules.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,300+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
5,000+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!