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Synthesis and Biological Evaluation of Schiff Bases and Azetidinones of 1-Naphthol

Published: Tuesday, September 04, 2012
Last Updated: Tuesday, September 04, 2012
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This study looks at the antibacterial and antifungal activity of these synthesized compounds.

Introduction

Schiff bases and azetidinones form an important structural class possessing wide spectrum of biological activities that include antibacterial and antifungal activity. A series of Schiff's bases N'-(substituted benzylidene)-2-(naphthalen-1-yloxy) acetohydrazides (3a-f) and azetidinones N-[3-chloro-2-oxo-4-(substituted phenyl)-azetidin-1-yl]-2-(naphthalen-1-yloxy) acetamides (4a-b) were synthesized and tested for antimicrobial activity.

This study is punlished online in the Journal of Pharmacy and Bioallied Sciences and is free to access.


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