Corporate Banner
Satellite Banner
Technology
Networks
Scientific Communities
 
Become a Member | Sign in
Home>News>This Article
  News
Return

COWIN to Develop New Lab-On-A-Chip Pathogen Testing Range

Published: Wednesday, September 12, 2012
Last Updated: Wednesday, September 12, 2012
Bookmark and Share
COWIN, a European initiative to facilitate the take-up of advanced technologies, is now helping the commercialisation phase of a European project to develop a Lab-on-a-Chip.

The concept of a Lab-on-a-Chip has been around for many years but this project, which has been co-ordinated by IK4-Ikerlan, has brought together over a dozen different companies from around Europe to contribute the various technologies needed to make it a success. Called LabOnFoil, it is now at the stage of having three different products that are at the field testing phase.

"There is always a danger that projects such as this can lose their way when researchers find something interesting and go off on a tangent," explained Dr Jesus Ruano, International Project Manager at IK4-Ikerlan. "To ensure that we kept on track and on budget, we used a very strict Product Design model where the form and functionality of every component was clearly specified at the start. This meant that we were bringing together a jigsaw where each component was precisely defined and that made the co-ordination and timing much easier. Now that we have the technologies and product design sorted, COWIN is playing a vital role in helping identify which application areas to focus on and what are the key differentiators over existing solutions that will make LabOnFoil successful in each target market. For example, for some applications such as pathogen testing or in an Accident and Emergency Department being able to provide test result in 30 minutes rather than two days is a tremendous advantage but for routine blood tests it is not."

Each LabOnFoil kit is designed to identify a particular type of DNA. The Pathogen testing range can identify either Campylobacter or Salmonella. The Pathology range is tuned to blood proteins whose presence indicates that a treated cancer patient does not have a re-occurrence of cancer. The Environmental range detects the presence of red algae that gives an indication of climate change as this causes algae blooms when the sea temperature rises. These all use a special, credit card-sized, plastic test unit -- a LabCard, which is pre-loaded with the appropriate reagents for the test required. The LabCard is made from injection moulded plastic with the appropriate reservoirs and valves as required for a particular specific analysis. A thin film of plastic is laminated on top to seal in the reagents and this is flexible enough to act as valves when moving the liquids though the various stages such as Polymerase Chain Reaction (PCR) to replicate and increase the DNA.

The sample is sucked up into the supplied syringe where it mixes with the initial reagents and is then squirted into a reservoir on the LabCard. The LabCard is then inserted into a LabCardReader reader unit that automatically heats the LabCard, and opens and closes the valves on it to move the test sample through the preparation stages. The last step is to detect fluorescence that indicates the presence of the target DNA which can be in concentrations at low as a few femtograms of DNA in 30 minutes.

Geraldine Adrieux Gustin, the COWIN coordinator, added, "We are now helping IK4-Ikerlan plan the strategy to develop this product line further with multi-pathogen detection, handheld readers that plug into smartphones, new markets, etc. Potential customers are very excited as there are now real working products that can offer significant advantages over the existing gold standards by being faster, cheaper, simpler, or more sensitive as required."


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,500+ scientific posters on ePosters
  • More Than 5,000+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.


Scientific News
Mass Spec Technology Drives Innovation Across the Biopharma Workflow
With greater resolving power, analytical speed, and accuracy, new mass spectrometry technology and techniques are infiltrating the biopharmaceuticals workflow.
One Step Closer to Precision Medicine for Chronic Lung Disease Sufferers
A study led by University of North Carolina at Chapel Hill, and National Jewish Health, has provided evidence of links between SNPs and known COPD blood protein biomarkers.
Gene Regulation in Brain May Explain Repetitive Behaviors in Rett Syndrome Patients
The research could be a key step in developing treatments to eliminate symptoms that drastically impair the quality of life in Rett patients.
Heart Arrhythmia Caused by Mosaic of Mutant Cells
Researchers have solved the genetic mystery of an infant suffering from heart arrhythmia.
Iron Nanoparticles Make Immune Cells Attack Cancer
Researchers accidentally discover that nanoparticles invented for anemia treatment can trigger the immune system’s ability to destroy tumor cells.
Crispr Toolbox Expanded By Protein
Researchers have shown a newly discovered CRISPR protein has two distinct RNA cutting activities.
CES Score May Predict Response to Cancer Treatment
Researchers identify new type of biomarker that helps predict prognosis and response to several types of cancer treatment.
Uncovering Cancer’s ‘Invisibility Cloak’
Researchers discover cancer cell mechanism to become invisible to the body's immune system.
Genetic Impact of Endurance Training
Research has found that endurance training changes genetic activity in thousands of genes, giving rise to large number of altered RNA variants.
Treating Sepsis with Marine Mitochondria
Mitochondrial alternative oxidase from a marine animal combats bacterial sepsis.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,500+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
5,000+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!