Corporate Banner
Satellite Banner
Technology
Networks
Scientific Communities
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Encap Drug Delivery Establishes Hot Melt Extrusion Capability

Published: Tuesday, October 09, 2012
Last Updated: Tuesday, October 09, 2012
Bookmark and Share
Company receives funding from the Technology Strategy Board and the Scottish Government that will allow both to enter into a collaborative Knowledge Transfer Partnership (KTP) on Hot Melt Extrusion (HME).

Encap is a contract development and manufacturing organisation (CDMO) which has pioneered the application of liquid and semi-solid filled hard capsules for pharmaceutical products. For more than 20 years the company has successfully applied the technology to a wide range of client new molecular entities (NMEs) which have required solubility and bioavailability enhancement. Since its inception the company has focused on gaining a sound scientific understanding of the formulation strategies which can be tailored to the individual characteristics of the target molecules and more importantly translating these formulations into scalable and commercial liquid filled pharmaceutical products.

It is the company's intention to apply a similar strategy to the development of HME products and Encap will differentiate itself from other development services companies by providing a sound scientific understanding of the technology. This will ensure that products are developed on a rigorous scientific basis and promote robust and scalable manufacturing processes which will enable clients to move quickly and efficiently through clinical development to registration and commercialisation.

Dr Jane Fraser said 'I am delighted to be working with Professor David Jones and Dr Gavin Andrews of QUB which is recognised as a world leader in the field of HME research. Encap is dedicated to providing world-class development and manufacturing services to its global clients and we are confident that we can establish and grow HME as a mainstream technology for poorly soluble molecules. We believe that this will be a valuable addition to the formulator's tool box and will fit well with our other enabling technologies'.

Dr Gavin Andrews reiterated the importance of the grant programme 'Specifically, our intention is that QUB will implement a robust, continuous melt extrusion process capable of engineering solid dispersions. In so doing we aim to complement existing soluble enhancement approaches through the addition of HME and thus bolster Encap's technologies portfolio'


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,300+ scientific posters on ePosters
  • More Than 4,900+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.


Scientific News
Breakthrough Flu Vaccine Inhibited by Pre-existing Antibodies
Universal truths – how existing antibodies are sabotaging the most promising new human flu vaccines.
Researchers Develop Software That Could Facilitate Drug Development
AptaTRACE can identify aptamers, potentially speed drug advancement.
Gene Therapy for Metabolic Liver Diseases
Researchers have tested gene therapy in pigs from hereditary tyrosinemia type 1, with corrected liver cells being transplanted into the diseased liver.
Zika Vaccine Candidates Show Promise
Two experimental vaccines have shown promise against a major viral strain responsible for the Brazilian Zika outbreak.
New Medication Shows Promise Against Liver Fibrosis in Animal Studies
Liver fibrosis is a gradual scarring of the liver that puts people at risk for progressive liver disease and liver failure.
Raw Eggs Deemed Safe to Eat
A report published today by the Advisory Committee on the Microbiological Safety of Food (ACMSF) into egg safety has shown a major reduction in the risk from salmonella in UK eggs.
Monitoring TTX Toxin in Shellfish
In a number of small studies, mussels and oysters from the eastern and northern part of the Oosterschelde in Holland were found to contain tetrodotoxin (TTX).
Gene Terapy for Muscle Wasting Developed
New gene therapy could save millions of people suffering from muscle wasting disease.
NIH Begins Yellow Fever Vaccine Trial
NIH has initiated an early-stage clinical trial of a vaccine to protect against yellow fever.
Gene-Editing 'Toolbox' Targets Multiple Genes Simultaneously
Researchers have designed a system that modifies, or edits, multiple genes in a genome at once while minimising unintentional effects.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,300+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,900+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!