Corporate Banner
Satellite Banner
Scientific Communities
Become a Member | Sign in
Home>News>This Article

Encap Drug Delivery Establishes Hot Melt Extrusion Capability

Published: Tuesday, October 09, 2012
Last Updated: Tuesday, October 09, 2012
Bookmark and Share
Company receives funding from the Technology Strategy Board and the Scottish Government that will allow both to enter into a collaborative Knowledge Transfer Partnership (KTP) on Hot Melt Extrusion (HME).

Encap is a contract development and manufacturing organisation (CDMO) which has pioneered the application of liquid and semi-solid filled hard capsules for pharmaceutical products. For more than 20 years the company has successfully applied the technology to a wide range of client new molecular entities (NMEs) which have required solubility and bioavailability enhancement. Since its inception the company has focused on gaining a sound scientific understanding of the formulation strategies which can be tailored to the individual characteristics of the target molecules and more importantly translating these formulations into scalable and commercial liquid filled pharmaceutical products.

It is the company's intention to apply a similar strategy to the development of HME products and Encap will differentiate itself from other development services companies by providing a sound scientific understanding of the technology. This will ensure that products are developed on a rigorous scientific basis and promote robust and scalable manufacturing processes which will enable clients to move quickly and efficiently through clinical development to registration and commercialisation.

Dr Jane Fraser said 'I am delighted to be working with Professor David Jones and Dr Gavin Andrews of QUB which is recognised as a world leader in the field of HME research. Encap is dedicated to providing world-class development and manufacturing services to its global clients and we are confident that we can establish and grow HME as a mainstream technology for poorly soluble molecules. We believe that this will be a valuable addition to the formulator's tool box and will fit well with our other enabling technologies'.

Dr Gavin Andrews reiterated the importance of the grant programme 'Specifically, our intention is that QUB will implement a robust, continuous melt extrusion process capable of engineering solid dispersions. In so doing we aim to complement existing soluble enhancement approaches through the addition of HME and thus bolster Encap's technologies portfolio'

Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,600+ scientific posters on ePosters
  • More Than 3,800+ scientific videos on LabTube
  • 35 community eNewsletters

Sign In

Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Scientific News
Fixing Holes in the Heart Without Invasive Surgery
UV-light enabled catheter is a medical device which represents a major shift in how cardiac defects are repaired.
Chromosomal Chaos
Penn study forms basis for future precision medicine approaches for Sezary syndrome
Enzyme Malfunction May be Why Binge Drinking Can Lead to Alcoholism
A new study in mice shows that restoring the synthesis of a key brain chemical tied to inhibiting addictive behavior may help prevent alcohol cravings following binge drinking.
Key to Natural Detoxifier’s Reactivity Discovered
Results have implications for health, drug design and chemical synthesis.
New Treatment for Obesity Developed
Researchers at the University of Liverpool, working with a global healthcare company, have helped develop a new treatment for obesity.
New Protein Found in Immune Cells
Immunobiologists from the University of Freiburg discover Kidins220/ARMS in B cells and demonstrate its functions.
Will Brain Palpation Soon Be Possible?
Researchers have developed non-invasive brain imaging technique which provides the same information as physical palpation.
Shaking Up the Foundations of Epigenetics
Researchers at the Centre for Genomic Regulation (CRG) and the University of Barcelona (UB) published a study that challenges some of the current beliefs about epigenetics.
Groundbreaking Computer Program Diagnoses Cancer in Two Days
Researchers have combined genetics with computer science and created a new diagnostic technology can with 85 per cent certainty identify the source of the disease and thus target treatment and, ultimately, improve the prognosis for the patient.
Michigan Researchers Use Raman Spectroscopy
inVia confocal Raman microscope used in the study of various childhood diseases.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,600+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
3,800+ scientific videos